Navigation Links
Recreational use of HIV antiretroviral drug linked to its psychoactivity
Date:4/21/2013

BOSTON More than 1 in 270 people in the US are living with HIV and every 9.5 minutes someone is else is infected. The economic cost estimates associated with HIV/AIDS exceed 36 billion dollars a year. The development of effective drug treatments have allowed people with HIV to live longer with federal health officials now predicting that by 2015 one-half of the population with HIV in the US will be older than 50.

Efavirenz (tradenames: Sustiva, Stocrin) is an antiretroviral (ARV) drug commonly used to treat HIV. Its popularity as a medication, alone or more commonly in combination with other HIV medications (tradename: Atripla), is due to its superior effectiveness in suppressing replication of the virus that causes AIDS. Though highly effective, a standard dose of efavirenz is known to carry a risk of side effects that include adverse neuropsychiatric complications such as depression, anxiety, sleep disturbances, impaired concentration, aggressive behavior, night terrors, hallucinations, paranoia, psychosis and delusions. However the question remains as to why these side effects occur. Recent anecdotal reports of the recreational use of efavirenz provided some clues.

Dr. John A. Schetz at the University of North Texas Health Science Center in Fort Worth, Texas, utilizes a mechanistic approach to solving problems and answering questions of importance to society. As a neuropharmacologist working to discover and develop new drugs for the treatment of neurological and psychiatric disorders, his experience and intuition helped solve the mystery as to why efavirenz, when taken as prescribed, can cause adverse psychiatric events, as well as why there are reports of efavirenz being diverted for recreational use. The later practice could encourage the emergence of ARV-resistant HIV strains by educating the HIV virus.

Dr. Schetz's interest was sparked by a network news report covering the topic of ARV abuse in South Africa. The report desc
'/>"/>

Contact: Jim Bernstein
jbernstein@aspet.org
301-646-3259
Federation of American Societies for Experimental Biology
Source:Eurekalert

Page: 1 2

Related biology news :

1. Early antiretroviral treatment reduces viral reservoirs in HIV-infected teens
2. Scientists find ethnicity linked to antibodies
3. A proteins well-known cousin sheds light on its gout-linked relative
4. Microorganisms detected via breath test linked to body mass, fat accumulation
5. Genetic alterations linked with bladder cancer risk, recurrence, progression, and patient survival
6. Global nitrogen availability consistent for past 500 years, linked to carbon levels
7. Reward linked to image is enough to activate brains visual cortex
8. Kids consumption of sugared beverages linked to higher caloric intake of food
9. Prenatal exposure to pesticide DDT linked to adult high blood pressure
10. 2 new genes linked to amyotrophic lateral sclerosis and related disorders
11. MBL scientists find genes linked to human neurological disorders in sea lamprey genome
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/21/2015)... 21, 2015 High crime ... are boosting access control systems market in ... a recently published report by TechSci Research " Saudi ... access control systems market in Saudi Arabia ... 2020.The access control systems market in the Kingdom is ...
(Date:4/14/2015)... 14, 2015  HYPR Corp. today announced it ... ) Alliance tm , an industry consortium transforming ... to share technology and collaborate to deliver open ... more secure and private, and easier to use. ... that protects sensitive user information and eliminates the ...
(Date:4/10/2015)... 2015 Research and Markets ( ... "Security Competitive Profiles - NEC" report to their ... NEC will continue to supply a range of IT ... a company focus on the development of a Big ... opportunities in the Asia-Pacific region ...
Breaking Biology News(10 mins):Saudi Arabia Access Control Systems Market to Touch USD1.2 Billion by 2020 Says TechSci Research 2Saudi Arabia Access Control Systems Market to Touch USD1.2 Billion by 2020 Says TechSci Research 3HYPR Corp. Joins the FIDO Alliance 2HYPR Corp. Joins the FIDO Alliance 3NEC Security Competitive Profile 2015 2
... Gretchen Daily, a professor of biology and senior fellow at ... been named one of 10 recipients of the 2010 Heinz ... Daily "for her innovative work to place a value on ... food etc.), which has resulted in increasing momentum towards the ...
... mechanical harvesting of perennial fruit crops requires efficient, economical ... or diminish fruit quality. Most of the world,s citrus ... and lower-cost mechanical harvesting techniques is expected to increase ... citrus plantations in Florida and Brazil. The citrus industry ...
... such an effort to forget about work while on vacation ... over in your head? Mathematicians at Case Western Reserve ... that just as thinking burns energy, stopping a thought burns ... "Maybe this explains why it is so tiring to ...
Cached Biology News:Stanford biologist Gretchen Daily to receive 2010 Heinz Award for environmental achievement 2Winter drought stress can delay flowering, prevent fruit loss in orange crops 2Food for thought, er, well... 2
(Date:5/1/2015)... 2015 Investor-Edge has initiated ... (NASDAQ: GENE ), Agilent Technologies Inc. (NYSE: ... TMO ), Sequenom Inc. (NASDAQ: SQNM ... Free research report on Genetic Technologies can be ... 30, 2015, the NASDAQ Composite ended at 4,941.42, ...
(Date:5/1/2015)... According to a new ... Consumables), by Type (Monoclonal, Polyclonal), by Technology (Hybridoma), ... - Analysis & Global Forecast to 2019", published ... Production Market for the forecast period of 2014 ... $2.572 Billion by 2019 from $1.425 Billion in ...
(Date:4/30/2015)... 2015 Spirax Sarco, the leader in ... to announce that for the first time in the ... of a Queen’s Award for Innovation – the UK’s ... manufacture of a unique flowmeter. , The Spirax Sarco ... traditional steam flow measurement. The device provides reliable, ...
(Date:4/30/2015)... SAN DIEGO , April 30, 2015   ... drugs, announced today an update on its Ebola antiviral ... of Tamir,s leading candidates, TMR004, is currently being evaluated ... frontline of the battle against Ebola. During the first ... Voice And Leadership Meeting To Accelerate The Evaluation of ...
Breaking Biology Technology:Life Sciences Tools and Services Stocks on our Radar -- Genetic Technologies, Agilent Technologies, Thermo Fisher Scientific, Sequenom, and PerkinElmer 2Life Sciences Tools and Services Stocks on our Radar -- Genetic Technologies, Agilent Technologies, Thermo Fisher Scientific, Sequenom, and PerkinElmer 3Life Sciences Tools and Services Stocks on our Radar -- Genetic Technologies, Agilent Technologies, Thermo Fisher Scientific, Sequenom, and PerkinElmer 4Life Sciences Tools and Services Stocks on our Radar -- Genetic Technologies, Agilent Technologies, Thermo Fisher Scientific, Sequenom, and PerkinElmer 5Antibody Production Market worth $2.572 Billion by 2019 2Antibody Production Market worth $2.572 Billion by 2019 3Antibody Production Market worth $2.572 Billion by 2019 4Spirax Sarco Receives a Queen’s Award for Innovation 2Spirax Sarco Receives a Queen’s Award for Innovation 3Tamir Biotechnology Provides Update on TMR004 Development Against Mutating Ebola 2Tamir Biotechnology Provides Update on TMR004 Development Against Mutating Ebola 3Tamir Biotechnology Provides Update on TMR004 Development Against Mutating Ebola 4
... money from the Minority Business Development Fund , the ... minority-owned technology businesses in Madison. , , Gov. Jim Doyle ... will receive loans to help them expand and create jobs. ... capital to develop and market a private, anonymous software transaction ...
... a fabulous year and outperformed the NASDAQ Composite index ... large margin. The two key biotech indices, the NASDAQ and ... each. , ,The NASDAQ Biotech Index, which holds many more ... industry (larger and smaller companies), was flat for the year, ...
... and BellSouth must simply be on a mission from ... one can stop them. , ,They waited until the last week ... U.S. history. I always thought that the old Bell System ... to proving I was right by continuing what I coined the ...
Cached Biology Technology:2006: A mixed blessing for Midwest life science companies 22006: A mixed blessing for Midwest life science companies 32006: A mixed blessing for Midwest life science companies 42006: A mixed blessing for Midwest life science companies 52006: A mixed blessing for Midwest life science companies 62006: A mixed blessing for Midwest life science companies 72006: A mixed blessing for Midwest life science companies 82006: A mixed blessing for Midwest life science companies 92006: A mixed blessing for Midwest life science companies 102006: A mixed blessing for Midwest life science companies 11AT&T - BellSouth merger: Revestiture continues 2AT&T - BellSouth merger: Revestiture continues 3AT&T - BellSouth merger: Revestiture continues 4AT&T - BellSouth merger: Revestiture continues 5AT&T - BellSouth merger: Revestiture continues 6
... 250 ul (125 precipitations). ... easy pellet location.Efficient precipitation ... inert, compatible with most ... protocol. Category: DNA/RNA Synthesis ...
EDTA, 0.5 M solution, 100 ml. Ethylene diaminetetraacetic acid.Sterile, nuclease-free. Category: Nucleotides & Enzymes & Biochemicals, Ultrapure Biochemicals ....
Recombinant Mouse sTNF RII/TNFRSF1B...
Mouse Wnt-11 Affinity Purified Polyclonal Ab...
Biology Products: