Navigation Links
Record-breaking grant: New research project to investigate the causes of mental disorders
Date:3/19/2012

Is it possible to prevent the development of schizophrenia? Can certain patients develop autism if they carry a specific gene and have been exposed to a viral fetal infection? Should all ADHD patients take the same type of medication?

This unique research project will try to answer these questions. The project is based at Aarhus University and will be known as 'The Lundbeck Foundation's Initiative for Integrative Psychiatric Research' (iPSYCH). The grant of DKK 121m from the Lundbeck Foundation is the largest grant ever awarded to Danish psychiatric research.

- We will investigate why some people develop mental disorders. We will identify biological disease mechanisms, and we also intend to provide the basis for better treatment and prevention, says Dr. Brglum, Professor of Medical Genetics at Aarhus University and Scientific Director of the research project.

The many faces of psychiatry

The project will study five specific mental disorders: schizophrenia, manic depression, depression, autism and ADHD. All disorders are associated with major human and societal costs all over the world. The new thing is that researchers will study these disorders from many different angles, ranging from genes and cells to population studies, from fetus to adult, from cause to symptoms of the disorder, and this knowledge will be combined in new ways across scientific fields.

- People suffering from a mental disorder such as schizophrenia may have very different lives: a family life with children and a job or a life characterized by chronic disease and homelessness. The disorders do not affect all patients in exactly the same way. We do not know why, but we do know that our current treatment methods are far from optimal because we need more knowledge about the causes behind the disorders, but also about the differences in the development, says Dr. Brglum.

- Our main goal is to identify the causes of these disorders by studying the interplay between genetic and environmental factors and thereby find new targets for treatment. The perspective is to offer better and individualized treatment, providing a better life for each individual patient with the disorder and perhaps even ways to prevent the development of the disorder in some cases, he says.

Professor Mikael Rrth, Chairman of the Board of Trustees of the Lundbeck Foundation, is pleased with the research opportunities that the new grant will offer:

- Mental disorders are determined by a combination of genetic and psycho-social factors. The research project will combine unique Danish registers and biobanks and is expected to pave the way for better treatment in the future, says Dr. Rrth.

International collaboration

iPSYCH consists of leading researchers within psychiatry, genetics and register-based research. The team collaborates with e.g. the SSI (Statens Serum Institut) under the Danish Ministry of Health, Beijing Genomics Institute (BGI), deCode Genetics in Iceland and the Genetic Biobank of the Faroe Islands. In combination, this will provide unique opportunities for creating ground breaking new knowledge, which may result in better and more individualized treatment of patients by considering genetic profile, environmental factors and clinical symptoms in combination.

The iPSYCH project team consists of the following researchers:

  • Professor Anders Brglum, Aarhus University and Aarhus University Hospital (Scientific Director of iPSYCH): anders@humgen.au.dk; tel: +45 8716 7768 or +45 60202720
  • Professor Ole Mors, Aarhus University and Aarhus University Hospital: nielmors@rm.dk; tel: + 45 7847 1166
  • Professor Preben Bo Mortensen, Aarhus University: pbm@ncrr.dk; tel:. +45 8716 5359
  • Professor Thomas Werge, Mental Health Services in the Capital Region of Denmark: thomas.werge@regionh.dk; tel: +45 4633 4968
  • Professor Merete Nordentoft, Mental Health Services in the Capital Region of Denmark: merete.nordentoft@regionh.dk; tel: +45 3531 6239.


'/>"/>

Contact: Kirsten Olesen
kol@sun.au.dk
(45) 23-38-24-44
Aarhus University
Source:Eurekalert

Related biology news :

1. Hot springs microbe yields record-breaking, heat-tolerant enzyme
2. Wistar Institute researcher receives New Innovator award from NIH
3. NC State researchers get to root of parasite genome
4. White Mountain Research Station to host climate change conference
5. Stevens awarded $1M for advanced biofuels research
6. Researchers find animal with ability to survive climate change
7. Researchers find an essential gene for forming ears of corn
8. Researchers note differences between people and animals on calorie restriction
9. Researcher working on destruction of chemical weapons
10. Researchers study acoustic communication in deep-sea fish
11. Researchers discover that growing up too fast may mean dying young in honey bees
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/20/2016)... 20, 2016  VoiceIt is excited to announce ... By working together, VoiceIt and VoicePass ... and VoicePass take slightly different approaches to voice ... security and usability. ... new partnership. "This marketing and technology ...
(Date:5/9/2016)... , UAE, May 9, 2016 ... when it comes to expanding freedom for high net ... Even in today,s globally connected world, there is ... conferencing system could ever duplicate sealing your deal with ... obtaining second passports by taking advantage of citizenship via ...
(Date:4/28/2016)... April 28, 2016 First quarter 2016:   ... 966% compared with the first quarter of 2015 The ... 589.1 M (loss: 18.8) and the operating margin was 40% (-13) ... Cash flow from operations was SEK 249.9 M (21.2) ... guidance is unchanged, SEK 7,000-8,500 M. The operating margin ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... , June 23, 2016 A person commits a ... crime scene to track the criminal down. An ... Food and Drug Administration (FDA) uses DNA evidence to track ... Sound far-fetched? It,s not. The FDA has increasingly ... support investigations of foodborne illnesses. Put as simply as possible, ...
(Date:6/23/2016)... Lawrence, MA (PRWEB) , ... June 23, 2016 ... ... the Peel Plate® YM (Yeast and Mold) microbial test has received AOAC Research ... test platform of microbial tests introduced last year,” stated Bob Salter, Vice President ...
(Date:6/23/2016)... -- The Biodesign Challenge (BDC), a university competition that asks ... systems and biotechnology, announced its winning teams at the ... York City . The teams, chosen ... MoMA,s Celeste Bartos Theater during the daylong summit. Keynote ... of architecture and design, and Suzanne Lee , ...
(Date:6/23/2016)... ... , ... Supplyframe, the Industry Network for electronics hardware design ... Located in Pasadena, Calif., the Design Lab’s mission is to bring together inventors ... and brought to market. , The Design Lab is Supplyframe’s physical representation of ...
Breaking Biology Technology: