Navigation Links
Recognizing blood poisoning quickly
Date:12/9/2011

Is the patient suffering from blood poisoning? To answer this question, the doctor draws a blood sample and sends it to a central laboratory for testing. This takes up valuable time, which could cost the patient his life. In future, physicians will be able to analyze blood there and then and have the results within twenty minutes. This is made possible by a biochip, developed by scientists at the Fraunhofer Institute for Physical Measurement Techniques IPM in Freiburg. "To analyze the biochip we have also designed a fully automatic device to carry out all the examination steps," explains Dr. Albrecht Brandenburg, group manager at the IPM. "All the doctor has to do is place the sample in the apparatus and wait for the results."

Meanwhile, within the device there's plenty going on: it starts by preparing the blood sample. Red blood cells are separated from the blood and the plasma that remains is guided onto the biochip. When patients are suffering from sepsis, their immune system reacts by producing certain proteins. The biochip uses these in its diagnosis: there are antibodies positioned on the chip which fit these proteins like a key fits a lock. If the proteins are present in the blood, the antibodies fish them out of the fluid and bind them to the chip. But how does the apparatus know if proteins have been caught? "The chip is rinsed with a solution containing the appropriate antibodies, which have in turn been marked with a fluorescent dye," explains IPM scientist Dr. Manuel Kemmler. "These bind to the proteins meaning antibodies, protein and marked antibodies are all firmly linked to each other and to the chip's surface. When the chip is illuminated, the dye lights up." The apparatus sees lots of little illuminated dots that show the protein was in the blood. If the patient is healthy, however, the chip remains dark.

The researchers can even test for different proteins at the same time in one cycle. This is done by placing various different catcher molecules on the chip, to which specific molecules in the blood attach themselves. A cunning selection of proven protein markers allows the scientists to obtain additional important information about the severity and cause of the illness.

Together with colleagues from a university hospital, the researchers have already successfully tested prototypes of the device and biochip. Each biochip can only be used once so they have to be affordable. "We predict that in the long run, with production on a large enough scale, each chip will cost no more than one euro," says Brandenburg. There are various possible applications: other conditions such as heart attacks or cancers can also be investigated this way. What's more, the chip facilitates doping and urine testing as well as the quality assessment of foodstuffs.


'/>"/>
Contact: Dr. Albrecht Brandenburg
albrecht.brandenburg@ipm.fraunhofer.de
49-761-885-7306
Fraunhofer-Gesellschaft
Source:Eurekalert  

Related biology news :

1. MIT: Why we have difficulty recognizing faces in photo negatives
2. Psychologists find skill in recognizing faces peaks after age 30
3. Recognizing gibbons from their regional accents
4. Scientist plans to test for blood pressure genes affected by age
5. Discovery of natural compounds that could slow blood vessel growth
6. New blood test for Down syndrome
7. On the trail of a targeted therapy for blood cancers
8. Lower your blood pressure, hydrate your skin and reduce dental plaque -- with chocolate?
9. Building the blood-brain barrier
10. Apelin hormone injections powerfully lower blood sugar
11. Battling bacteria in the blood: Researchers tackle deadly infections
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Recognizing blood poisoning quickly
(Date:4/5/2017)... Allen Institute for Cell Science today announces the launch ... dynamic digital window into the human cell. The website ... deep learning to create predictive models of cell organization, ... suite of powerful tools. The Allen Cell Explorer will ... resources created and shared by the Allen Institute for ...
(Date:4/4/2017)...   EyeLock LLC , a leader of iris-based ... Patent and Trademark Office (USPTO) has issued U.S. Patent ... an iris image with a face image acquired in ... 45 th issued patent. "The ... the multi-modal biometric capabilities that have recently come to ...
(Date:3/30/2017)... HONG KONG , March 30, 2017 ... developed a system for three-dimensional (3D) fingerprint identification by adopting ground ... technology into a new realm of speed and accuracy for use ... applications at an affordable cost. ... ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... ... of a complex biological network, a depiction of a system of linkages and ... Dmitry Korkin, PhD, associate professor of computer science at Worcester Polytechnic Institute (WPI) ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... Vilnius, Lithuania, announced today that they have entered into a multiyear collaboration to ... provide CRISPR researchers with additional tools for gene editing across all applications. , ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... with the addition of its newest module, US Hemostats & Sealants. , SmartTRAK’s ... hemostats, absorbable hemostats, fibrin sealants, synthetic sealants and biologic sealants used in surgical ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... analysis platform specifically designed for life science researchers to analyze and interpret ... Rosalind Franklin, who made a major contribution to the discovery of the ...
Breaking Biology Technology: