Navigation Links
Recognizing blood poisoning quickly
Date:12/9/2011

Is the patient suffering from blood poisoning? To answer this question, the doctor draws a blood sample and sends it to a central laboratory for testing. This takes up valuable time, which could cost the patient his life. In future, physicians will be able to analyze blood there and then and have the results within twenty minutes. This is made possible by a biochip, developed by scientists at the Fraunhofer Institute for Physical Measurement Techniques IPM in Freiburg. "To analyze the biochip we have also designed a fully automatic device to carry out all the examination steps," explains Dr. Albrecht Brandenburg, group manager at the IPM. "All the doctor has to do is place the sample in the apparatus and wait for the results."

Meanwhile, within the device there's plenty going on: it starts by preparing the blood sample. Red blood cells are separated from the blood and the plasma that remains is guided onto the biochip. When patients are suffering from sepsis, their immune system reacts by producing certain proteins. The biochip uses these in its diagnosis: there are antibodies positioned on the chip which fit these proteins like a key fits a lock. If the proteins are present in the blood, the antibodies fish them out of the fluid and bind them to the chip. But how does the apparatus know if proteins have been caught? "The chip is rinsed with a solution containing the appropriate antibodies, which have in turn been marked with a fluorescent dye," explains IPM scientist Dr. Manuel Kemmler. "These bind to the proteins meaning antibodies, protein and marked antibodies are all firmly linked to each other and to the chip's surface. When the chip is illuminated, the dye lights up." The apparatus sees lots of little illuminated dots that show the protein was in the blood. If the patient is healthy, however, the chip remains dark.

The researchers can even test for different proteins at the same time in one cycle. This is done by placing various different catcher molecules on the chip, to which specific molecules in the blood attach themselves. A cunning selection of proven protein markers allows the scientists to obtain additional important information about the severity and cause of the illness.

Together with colleagues from a university hospital, the researchers have already successfully tested prototypes of the device and biochip. Each biochip can only be used once so they have to be affordable. "We predict that in the long run, with production on a large enough scale, each chip will cost no more than one euro," says Brandenburg. There are various possible applications: other conditions such as heart attacks or cancers can also be investigated this way. What's more, the chip facilitates doping and urine testing as well as the quality assessment of foodstuffs.


'/>"/>
Contact: Dr. Albrecht Brandenburg
albrecht.brandenburg@ipm.fraunhofer.de
49-761-885-7306
Fraunhofer-Gesellschaft
Source:Eurekalert  

Related biology news :

1. MIT: Why we have difficulty recognizing faces in photo negatives
2. Psychologists find skill in recognizing faces peaks after age 30
3. Recognizing gibbons from their regional accents
4. Scientist plans to test for blood pressure genes affected by age
5. Discovery of natural compounds that could slow blood vessel growth
6. New blood test for Down syndrome
7. On the trail of a targeted therapy for blood cancers
8. Lower your blood pressure, hydrate your skin and reduce dental plaque -- with chocolate?
9. Building the blood-brain barrier
10. Apelin hormone injections powerfully lower blood sugar
11. Battling bacteria in the blood: Researchers tackle deadly infections
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Recognizing blood poisoning quickly
(Date:12/2/2016)... PUNE, India , December 1, 2016 /PRNewswire/ ... Market by Authentication type (Fingerprint, Voice), Future Technology (Iris ... Vehicle), and Region - Global Forecast to 2021", ... be USD 442.7 Million in 2016, and is ... 2021, at a CAGR of 14.06%. ...
(Date:11/30/2016)... 2016  higi SH llc (higi) announced today ... national brands, industry thought-leaders and celebrity influencers looking ... for taking steps to live healthier, more active ... higi has built the largest self-screening health station ... people who have conducted over 185 million biometric ...
(Date:11/29/2016)... Nearly one billion matches per second with DERMALOG,s high-speed AFIS    ... ... DERMALOG is Germany's largest Multi-Biometric supplier: The company's ... Systems) ... largest Multi-Biometric supplier: The company's Fingerprint Identification System is part of an ...
Breaking Biology News(10 mins):
(Date:12/8/2016)... 2016 Savannah River Remediation LLC group ... NewTechBio,s NT-MAX Lake & Pond Sludge and ... in conjunction with Hexa Armor/ Rhombo cover manufactured ... Pollutant Discharge Elimination System requirements. The ... history of elevated pH levels, above 8.5, especially ...
(Date:12/7/2016)... ... December 07, 2016 , ... ACEA Biosciences, Inc. presented today ... clinical trial for its lead drug candidate, AC0010, at the World Conference on ... to determine the safety, antitumor activity, and recommended phase II dosage of AC0010 ...
(Date:12/7/2016)... 2016 /PRNewswire/ - OncoQuest Inc. ("OncoQuest"), a biopharmaceutical ... immunotherapeutic products for the treatment of cancer, today ... Manufacturing Development Program with Cytovance Biologics ( ... oregovomab antibody product. Supported by recent positive interim ... in ovarian cancer patients, OncoQuest has engaged Cytovance ...
(Date:12/7/2016)... The report "Acrylic Processing Aid Market by Polymer Type (PVC), Fabrication Process (Extrusion, Injection ... to 2026", published by MarketsandMarkets, the global market size was USD 645.4 Million ... an of CAGR of 6.2% between 2016 and 2026. ... ... , , ...
Breaking Biology Technology: