Navigation Links
Recipe for capturing authentic embryonic stem cells may apply to any mammal, study suggests
Date:12/24/2008

Researchers have what they think may be a basic recipe for capturing and maintaining indefinitely the most fundamental of embryonic stem cells from essentially any mammal, including cows, pigs and even humans. Two new studies reported in the December 26th issue of the journal Cell, a Cell Press publication, show that a cocktail first demonstrated to work in mice earlier this year, which includes inhibitory chemicals, also can be used to successfully isolate embryonic stem cells from rats.

Authentic rat embryonic stem cells had never before been established.

The new discovery made in labs at both the University of Edinburgh and the University of Southern California (USC), Los Angeles, is a major breakthrough for biomedical research, said Qi-Long Ying, an author on both studies who was at the University of Edinburgh and is now at USC. That's because it will allow researchers to readily produce genetically altered strains of rats, with conditions that mimic human disease, in a very targeted way. Austin Smith led the team at the University of Edinburgh and Ying led the USC team.

Humans and rats are physiologically more similar than humans and mice, making the study of rats more directly applicable to people, and rats' larger size also makes them easier to work with in many cases, according to the researchers. Humans and rats also tend to have similar responses to drugs.

The findings lend support to the notion that embryonic stem cells will remain in their undifferentiated, pluripotent state when they are shielded from particular outside signals. (Pluripotent refers to the ability to differentiate into any cell or tissue type). Scientists had previously thought that the maintenance of stem cells depended on activating signals from outside, including growth factors and other chemicals.

Embryonic stem cells are derived from the inner cell mass of blastocysts. Blastocysts are hollow balls of cells that form in early
'/>"/>

Contact: Cathleen Genova
cgenova@cell.com
617-397-2802
Cell Press
Source:Eurekalert

1

GOOD

Page: 1 2 3

Related biology news :

1. High blood pressure, low energy -- a recipe for heart failure
2. Princeton engineers develop low-cost recipe for patterning microchips
3. Simple recipe turns human skin cells into embryonic stem cell-like cells
4. A recipe for saving the worlds oceans from an extinction crisis
5. IdentiPHI Introduces Biometric Authentication Solution for Citrix Web Interface Environments
6. Fidelica Microsystems Announces Biometrically-Authenticated Smart Card
7. FCO and GSSC Team to Create Worlds First Self-Authenticating Passport
8. Entrust, Hewlett Packard Partner to Deploy Taiwanese ePassports, Authenticate Biometric Data
9. Scientists identify embryonic stem cells by appearance alone
10. Embryonic stem cell strategy advanced with UCSF finding
11. Human embryonic stem cells remain embryonic because of epigenetic factors

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/4/2009)...PORTOLA VALLEY, Calif., Oct. 19 Sp...ecular sensing and imaging devices which shed ligh...at it has signed exclusive distribution deals for ...ors. The markets covered include Australia, New Z...elux), Suriname, Italy, France, Spain, Portugal, P...
(Date:11/4/2009)...REDWOOD CITY, Calif., Oct. 20 Digi... and authentication solutions, today announced tha...-sale (POS) software for quick-service restaurants...eir NextGen POS and Classic POS solutions. WAND,s ...ometrics to boost cashier accountability and deter...
(Date:11/4/2009)...RIDGE, N.Y., Oct. 21 What,s the co...enting accidental death resulting from prescriptio...with good intentions, however, may be unaware that...ng their teens from the ticking timebomb of prescr...ader in premium-quality medical supplies, has form...
Breaking Biology News(10 mins):Spectros Signs New International Distribution Deals 2WAND Point-of-Sale Solutions Integrate U.are.U(R) Fingerprint Biometrics From DigitalPersona for Quick-Service Restaurants 2WAND Point-of-Sale Solutions Integrate U.are.U(R) Fingerprint Biometrics From DigitalPersona for Quick-Service Restaurants 3MEDNET Launches MedSafe to Prevent Teenage Prescription Drug Abuse 2MEDNET Launches MedSafe to Prevent Teenage Prescription Drug Abuse 3Availity Provides Real Time Access to WellCare 55281 1Availity Provides Real Time Access to WellCare 55281 2SamarionSolution Installed in Covington Retirement Community 55279 1SamarionSolution Installed in Covington Retirement Community 55279 2Fast Forward LLC and Amplimmune Inc Join Forces to Speed New Treatments to People with MS 13684 1Fast Forward LLC and Amplimmune Inc Join Forces to Speed New Treatments to People with MS 13684 2Fast Forward LLC and Amplimmune Inc Join Forces to Speed New Treatments to People with MS 13684 3Fast Forward LLC and Amplimmune Inc Join Forces to Speed New Treatments to People with MS 13684 4
...inceton biologist reports at AAAS on partnership w... endangered Grevy,s zebra conservation , The Grevy...e family in the world, with an estimated 2000 left...n the Samburu region of northern Kenya, most of th...ve partnership between Princeton University and Sa...
... organism widely used for genetics-versus-environm...dogs, humans and other species whose entire genome...onsortium,s annual meeting in Bloomington this wee...cientists announced they,ve completed a "shotgun" ...it,s better known to high school biology students....
...n may cringe at the idea, but sperm-producing stem...n in the lab, and frozen for future use. A team in...togonial stem cells from cows and cultured them in... could be done for men. "This is a very promising ...motherapy," Dirk de Rooij of Utrecht University, N...
Other Biology News:Bringing the zoos to the zebras 2Bringing the zoos to the zebras 3Genome sequencing is for ecologists, too 2Testes to incubate stem cells 2
(Date:11/5/2009)...ire/ -- SpineSmith Partners has signed an initial ...ue scaffold that mimics the structure of natural c...ommercial products by SpineSmith,s Research and De...Osteo scaffold represents a significant advancemen...vironment for the delivery of adult stem cells for...
(Date:11/5/2009)...ery and vision correction experts listed in the Tr...ved at the recently concluded American Academy of ...ncisco, California. Dr. Stephen Brint, MD, Dr. Fre... Dr. Peter Rapoza, MD, Dr. Michael Raizman, MD, Dr... Edward Manche, MD, and Dr. Parag Majmudar, MD, al...
(Date:11/4/2009)...Anthrax Vaccine Program must be stopped. Scott Mi...uot;A Call to Arms:2009 Edition" and the one-...The Human Anthrax Vaccine Story" to inform th... secret government science turned into for-profit ...ts victims. It is available for world-wide licens...
(Date:11/4/2009)... 4 Zyngenia, Inc., a privately hel...on antibody drug development, today announced that...om New Enterprise Associates (NEA), one of the wor...ll be used to create novel, multi-specific antibod...al targets with a single agent. The company will i...
Breaking Biology Technology:SpineSmith Partners and GenOsteo Announce Collaborative Product Development Agreement 2Leading Vision Correction Experts in Trusted LASIK Surgeons Directory Educate Fellow Doctors at AAO Annual Meeting 2Leading Vision Correction Experts in Trusted LASIK Surgeons Directory Educate Fellow Doctors at AAO Annual Meeting 3Leading Vision Correction Experts in Trusted LASIK Surgeons Directory Educate Fellow Doctors at AAO Annual Meeting 4Leading Vision Correction Experts in Trusted LASIK Surgeons Directory Educate Fellow Doctors at AAO Annual Meeting 5Leading Vision Correction Experts in Trusted LASIK Surgeons Directory Educate Fellow Doctors at AAO Annual Meeting 6Leading Vision Correction Experts in Trusted LASIK Surgeons Directory Educate Fellow Doctors at AAO Annual Meeting 7Leading Vision Correction Experts in Trusted LASIK Surgeons Directory Educate Fellow Doctors at AAO Annual Meeting 8Leading Vision Correction Experts in Trusted LASIK Surgeons Directory Educate Fellow Doctors at AAO Annual Meeting 9Scott Miller's 'A Call To Arms' And 'Fatal Immunity' Are Available For World-Wide Licensing 2Scott Miller's 'A Call To Arms' And 'Fatal Immunity' Are Available For World-Wide Licensing 3Scott Miller's 'A Call To Arms' And 'Fatal Immunity' Are Available For World-Wide Licensing 4Scott Miller's 'A Call To Arms' And 'Fatal Immunity' Are Available For World-Wide Licensing 5Scott Miller's 'A Call To Arms' And 'Fatal Immunity' Are Available For World-Wide Licensing 6Scott Miller's 'A Call To Arms' And 'Fatal Immunity' Are Available For World-Wide Licensing 7Zyngenia, Inc. Raises $10 Million in Series A Funding 2Zyngenia, Inc. Raises $10 Million in Series A Funding 3Zyngenia, Inc. Raises $10 Million in Series A Funding 4
...,Transformation, Not Transactions, as the Necessar...WASHINGTON, Oct. 2 Deloitte & Touche USA LLP Life... will lead a discussion on,the intricacies of conv...idst increased competition, R&D stagnation, expand...h care costs, companies in all sectors,of the life...
...T, Calif., Oct. 2 Kiwa,Bio-Tech Products Group Co...ed that the Tianjin Kiwa Feed Limited Liability Co...ped 2,700 tons of animal feed during the,month of ...stated, "We are pleased with the,growth in volume ... tons,during the third quarter compared to approxi...
...t. 2 /PRNewswire/ - Respironics, Inc. (Nasdaq:,RES...e outstanding shares,of Apollo Light Systems, Inc....ing manufacturer of light therapy systems for mela...ders. Operating under the name Apollo Health,the c...nnual revenues of,approximately $5 million. The ba...
Other Biology Technology:Deloitte Leadership Offers Crucial Convergence Considerations for Life Sciences Companies 2Deloitte Leadership Offers Crucial Convergence Considerations for Life Sciences Companies 3Deloitte Leadership Offers Crucial Convergence Considerations for Life Sciences Companies 4Kiwa Bio-Tech Ships 2,700 Tons of Bio-feed in One Month 2Respironics Acquires Apollo Light Systems, Inc., Expands into Circadian Rhythm Device-Based Therapy Market 2Respironics Acquires Apollo Light Systems, Inc., Expands into Circadian Rhythm Device-Based Therapy Market 3
Rabbit Anti-DAP12 Polyclonal Antibody, Unconjugated from Exalpha Biologicals, Inc.
Rabbit Anti-Burkholderia pseudomallei Flagellin Polyclonal Antibody, Unconjugated from Abcam
Amido Black 10B, CI 20470 from Research Organics, Inc.
Calf Liver tRNA from Novagen
Biology Products: