Navigation Links
Realizing the promise of RNA nanotechnology for new drug development
Date:9/4/2012

New Rochelle, NY, September 4, 2012The use of RNA in nanotechnology applications is highly promising for many applications, including the development of new therapeutic compounds. Key technical challenges remain, though, and the challenges and opportunities associated with the use of RNA molecules in nanotechnology approaches are presented in a review article in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. The article is available free online at the Nucleic Acid Therapeutics website.

Peixuan Guo and colleagues, University of Kentucky, Lexington, highlight the ability of RNA to self-assemble into nanoparticles with diverse structures. In "Uniqueness, Advantages, Challenges, Solutions, and Perspectives in Therapeutics Applying RNA Nanotechnology," the authors provide a detailed description of the main challenges faced by the RNA therapeutics industry, including the chemical and thermodynamic instability of the molecules, potential safety and side effect issues, difficulties in delivery and specific targeting, and low yield and high production costs in manufacturing.

"The remarkable structural and enzymatic properties of RNA continue to astound us," says Executive Editor Fintan Steele, PhD, SomaLogic, Inc., Boulder, CO. "It is exciting to see those properties increasingly realized for the benefit of human health and welfare, as described by Dr. Guo and his colleagues."


'/>"/>

Contact: Vicki Cohn
vcohn@liebertpub.com
914-740-2100 x2156
Mary Ann Liebert, Inc./Genetic Engineering News
Source:Eurekalert  

Page: 1

Related biology news :

1. KIT researchers succeed in realizing a new material class
2. New study shows promise in using RNA nanotechnology to treat cancers and viral infections
3. Silicone foul release coatings show promise to manage invasive mussels at water facilities
4. Common antifungal drug decreases tumor growth and shows promise as cancer therapy
5. New drug shows promise for kidney disease
6. Nanoscale scaffolds and stem cells show promise in cartilage repair
7. New compound holds promise for treating Duchenne MD, other inherited diseases
8. A sea of broken promises
9. New stem cell technique promises abundance of key heart cells
10. Transcatheter aortic valve implantation shows promise in patients with severe aortic stenosis
11. Innovative cell printing technologies hold promise for tissue engineering R&D
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Realizing the promise of RNA nanotechnology for new drug development
(Date:11/24/2016)... 2016 Cercacor today introduced Ember TM ... non-invasively measure hemoglobin, Oxygen Content, Oxygen Saturation, ... Rate in approximately 30 seconds. Smaller than a smartphone, ... access to key data about their bodies to help ... Hemoglobin carries oxygen to muscles. When ...
(Date:11/21/2016)... , Nov. 21, 2016   Neurotechnology , ... recognition technologies, today announced that the MegaMatcher On ... was submitted for the NIST Minutiae Interoperability ... all the mandatory steps of the evaluation protocol. ... a continuing test of fingerprint templates used to ...
(Date:11/17/2016)... INDUSTRY, Calif. , Nov. 17, 2016  AIC announces that it has just ... servers in organizations that require high-performance scale-out plus high speed data transfer storage solutions. ... ... ... Setting up a ...
Breaking Biology News(10 mins):
(Date:12/2/2016)... San Antonio Texas (PRWEB) , ... ... ... announced today that it will share findings demonstrating the value of DNA ... cancer patients at this year’s San Antonio Breast Cancer Symposium. Using molecular ...
(Date:12/2/2016)... ... December 01, 2016 , ... Orthogonal, a Chicago-based medical ... FDA Class II 510(k) clearance for their flagship medical device, SimplECG. , With ... monitoring devices that rely on cloth-based nanosensors. While other companies have attempted to ...
(Date:12/2/2016)... world leader in rapid infectious disease tests, introduced the Company,s newest product, the INSTI ... (Photo: http://photos.prnewswire.com/prnh/20161201/444905 ) Continue Reading ... ... , bioLytical was invited by the Clinton ... HIV Self Test to 350 pharmacy representatives in Nairobi and ...
(Date:11/30/2016)... Nov. 30, 2016 Biotest Pharmaceuticals Corporation (BPC), ... to announce the addition of its newest plasma collection ... Nebraska . The 15,200 square foot state-of-the-art facility ... 2016 and brings the total number of BPC,s plasma ... Carlisle , BPC,s Chief Executive Officer said "We are ...
Breaking Biology Technology: