Navigation Links
Reading history through genetics
Date:12/5/2012

d genetically isolated while their population has expanded rapidly to several millions today.

"Knowing that the Ashkenazi population has expanded so recently from a very small number has practical implications," notes Pe'er. "If we can obtain data on only a few hundreds of individuals from this population, a perfectly feasible task in today's technology, we will have effectively collected the genomes of millions of current Ashkenazim." He and his team are now doing just that, and have already begun to analyze a first group of about 150 Ashkenazi genomes.

The genetic data of the Masai, a semi-nomadic people, indicates the village-by-village structure of their population. Unlike the isolated Ashkenazi group, the Masai live in small villages but regularly interact and intermarry across village boundaries. The ancestors of each village therefore typically come from many different places, and a single village hosts an effective gene pool that is much larger than the village itself.

Previous work in population genetics was focused on mutations that occurred very long ago, say the researchers, and therefore able to only describe population changes that occurred at that timescale, typically before the agricultural revolution. Pe'er's research has changed that, enabling scientists to learn more about recent changes in populations and start to figure out, for instance, how to pinpoint severe mutations in personal genomes of specific individualsmutations that are more likely to be associated with disease.

"This is a thrilling time to be working in computational genetics," adds Pe'er, citing the speed in which data acquisition has been accelerating; much faster than the ability of computing hardware to process such data. "While the deluge of big data has forced us to develop better algorithms to analyze them, it has also rewarded us with unprecedented levels of understanding."


'/>"/>

Contact: Holly Evarts
holly.evarts@columbia.edu
347-453-7408
Columbia University
Source:Eurekalert

Page: 1 2

Related biology news :

1. MindSpec launches online Autism Reading Room
2. New model of disease contagion ranks US airports in terms of their spreading influence
3. Flightless molecule may prevent cancer from spreading from 1 tissue to another
4. Frequent traveller: Dysentery-causing bacteria spreading from Europe to Australia
5. Brain-wave-reading robot might help stroke patients
6. New book on stereology by Mark West is essential reading for neurobiologists
7. Joint UT study: Reading food labels helps shoppers stay thinner
8. Scientists trace evolutionary history of what mammals eat
9. Family history of liver cancer increases risk of developing the disease
10. Earth history and evolution
11. New coelacanth find rewrites history of the ancient fish
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2015)... 2015 SoundView Technology Group issues a new research ... ) Wocket smart wallet. SoundView was one of the selected user ... with the Wocket in multiple scenarios and outlets. ... other retailers, making both debit and credit card payments.  ... "If the company meets their plans in 2015, it would ...
(Date:3/20/2015)... DUBLIN , Mar. 20, 2015 Research ... announced the addition of the "India Sensors ... their offering. The sensor market is ... through 2020 Consumer electronics, automotive, industrial ... for sensors in the country. In addition, adoption ...
(Date:3/19/2015)... March 19, 2015  NXT-ID, Inc. (NASDAQ: NXTD ... on the growing mobile commerce market, announces its biometric payment ... clip that aired this week on Washington DC,s ... In a segment "The Next Great Thing", host ... way to pay, and ,a really big breakthrough in mobile ...
Breaking Biology News(10 mins):Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 2Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 3Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 4India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 2India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 3NXT-ID's Wocket Smart Wallet Featured on Fox News Segment, "The Next Great Thing" 2NXT-ID's Wocket Smart Wallet Featured on Fox News Segment, "The Next Great Thing" 3
... TAMPA, Fla. (Nov. 19, 2012) In three studies published in ... of the National Academy of Inventors , innovators unveil creative ... of energy, and change our lives. Untapped energy in ... and in Florida,s ocean waves can be captured and used, said ...
... has applied for a patent for a genetically-engineered vaccine strategy ... body structures that are the first sites of contact with ... last a lifetime, the vaccine will lead to the continual ... system. Another feature of the vaccine system is that it ...
... with histonesthe proteins that package DNAregulate many fundamental cell activities ... or blood cells becoming leukemic. These interactions are governed by ... chemically modify histones signaling them to clamp down tighter on ... expressed. In the November 19, 2012, online ...
Cached Biology News:New energy technologies promise brighter future 2New energy technologies promise brighter future 3Texas Biomed files patent for a novel HIV vaccine strategy 2Fruit fly studies guide investigators to misregulated mechanism in human cancers 2Fruit fly studies guide investigators to misregulated mechanism in human cancers 3
(Date:4/23/2015)... CA (PRWEB) April 23, 2015 Athena ... personal development of executive women in San Diego’s technology ... the 17th Annual Pinnacle Awards at their Gala on ... Hyatt Hotel. Register now at http://athenasd.org/events/ , ... support the Athena San Diego vision of fostering networking, ...
(Date:4/23/2015)... , April 23, 2015  Neurocrine Biosciences, Inc. (Nasdaq: ... report its first quarter 2015 results before the Nasdaq ... then host a live conference call and webcast to discuss ... morning, April 30, 2015 at 8:00 a.m. Eastern Time ... the live conference call by dialing 866-952-1906 (US) or ...
(Date:4/23/2015)... Prospects for Leading Companies in ... Details   We predict the global healthcare ... in 2015 and will grow at a CAGR of 6.3% ... around the world and increasing functional requirements for healthcare packaging ... global healthcare packaging market. A global ageing population, ...
(Date:4/23/2015)... April 23, 2015 /PRNewswire/ - Crystal Research Associates, LLC ... Overview ® (EIO) on Aeterna Zentaris Inc. (NASDAQ: ... available on Crystal Research Associates, website at ... website at www.aezsinc.com . Aeterna Zentaris ... biopharmaceutical company in oncology, endocrinology, and women,s health. With ...
Breaking Biology Technology:Athena Pinnacle Awards to Honor Executives, Corporations and Educators Working to Promote Women Leaders 2Neurocrine Biosciences Announces Conference Call and Webcast to Report First Quarter 2015 Results 2Healthcare Packaging Market Forecast 2015-2025 2Healthcare Packaging Market Forecast 2015-2025 3Healthcare Packaging Market Forecast 2015-2025 4Healthcare Packaging Market Forecast 2015-2025 5Healthcare Packaging Market Forecast 2015-2025 6Healthcare Packaging Market Forecast 2015-2025 7Healthcare Packaging Market Forecast 2015-2025 8Healthcare Packaging Market Forecast 2015-2025 9Healthcare Packaging Market Forecast 2015-2025 10Crystal Research Associates, LLC Issues Executive Informational Overview (EIO) on Aeterna Zentaris Inc. 2Crystal Research Associates, LLC Issues Executive Informational Overview (EIO) on Aeterna Zentaris Inc. 3
... Hospital (TSH),Canada,s largest urban community hospital, has selected ... physicians. The,implementation of Chyma(TM) for their team of ... ER departments at the two hospital campuses and ... medicine., "Chyma(TM) reflects the commitment of the ...
... Mass., June 2 RainDance Technologies, Inc.,a ... health and,disease research, today announced the appointment ... effective immediately., "As RainDance solutions enter ... to establish our manufacturing and financial capabilities,",said ...
... announced the,release of a new and exciting module ... experience with different techniques and,alternative approaches to the ... The GYN module is the latest addition to ... Mentor, the world,s most advanced,laparoscopic surgery simulator. The ...
Cached Biology Technology:Canada's Largest Urban Community Hospital Chooses Chyma(TM) On-Call Physician Scheduling Technology 2RainDance Appoints Kelly Chief Operating Officer 2Simbionix Takes Non-Invasive GYN Surgical Training to the Next Level 2
Used in May-Grunwald Giemsa stain....
Certified U.S. origin. Bovine Serum:, *Certified U.S. origin. Available raw, nonsterile filtered, or sterile filtered. , , *Sterility tested , , *Low Hemoglobin levels , , *Mycoplasma testing upon...
The Magnetic Separation Rack is designed to be used for small-scale separations using magnetic particles. ,Capacity: 6 microcentrifuge tubes....
... atoms at the 9, 10, 12, and 13 ... internal standard for the quantification of 9(S)-HODE by ... the lipoxygenation of linoleic acid in both plants ... plaques, as an esterified component of membrane phospholipids ...
Biology Products: