Navigation Links
Rattlesnake-type poisons used by superbug bacteria to beat our defenses
Date:9/7/2008

Colonies of hospital superbugs can make poisons similar to those found in rattlesnake venom to attack our bodies' natural defences, scientists heard today (Monday 8 September 2008) at the Society for General Microbiology's Autumn meeting being held this week at Trinity College, Dublin.

The toxins are manufactured by communities of the hospital superbug Pseudomonas aeruginosa called biofilms, which are up to a thousand times more resistant to antibiotics than free-floating single bacterial cells.

"This is the first time that anyone has successfully proved that the way the bacteria grow either as a biofilm, or living as individuals affects the type of proteins they can secrete, and therefore how dangerous they can potentially be to our health," says Dr Martin Welch from the University of Cambridge, UK.

"Acute diseases caused by bacteria can advance at an astonishing rate and tests have associated these types of disease with free-floating bacteria. Such free-floating bugs often secrete tissue-damaging poisons and enzymes to break down our cells, contributing to the way the disease develops, so it is natural to blame them. By contrast, chronic or long-term infections seem to be associated with biofilms, which were thought to be much less aggressive," says Dr Welch.

The research team's findings are very important to the NHS, which spends millions of pounds every year fighting chronic long-term bacterial infections which are incredibly difficult to treat.

"For example, these chronic infections by bacteria are now the major cause of death and serious disability in cystic fibrosis patients which is the most common lethal inherited disease in the UK and affects about 8,000 people," says Dr Welch.

In cystic fibrosis the gene defect means that people are very susceptible to a particular group of opportunistic bacteria including Pseudomonas aeruginosa, which is one of the three major hospital superbugs. Aggressive an
'/>"/>

Contact: Lucy Goodchild
l.goodchild@sgm.ac.uk
44-078-248-83010
Society for General Microbiology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Developing kryptonite for Superbug
2. Decoy makes sitting duck of superbugs
3. Green tea helps beat superbugs
4. New antibiotic beats superbugs at their own game
5. Shuttle brings space-grown strep bacteria back for study
6. The worlds oldest bacteria
7. Bacteria from sponges make new pharmaceuticals
8. Boston University biomedical engineers find chink in bacterias armor
9. University of Leicester scientists discover technique to help friendly bacteria
10. Spaceflight shown to alter ability of bacteria to cause disease
11. A tiny pinch from a z-ring helps bacteria cells divide
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/10/2014)... Dec. 9, 2014 CIE San Diego has ... provides the connective tissue that enhances care coordination among ... easily share client-level information; earned a second $1 million ... organizations serving seniors aging in community and; will be ... December 11 th 4-6p. CIE San ...
(Date:12/10/2014)... California , December 9, 2014 ... with ITN,s BCARD Platform   ... cloud-based enterprise meeting scheduling solutions for business-to-business (B2B) ... the world leader in mobile near-field communication (NFC), ...      (Logo: http://photos.prnewswire.com/prnh/20140612/691055) , ...
(Date:12/5/2014)... 2014  Tute Genomics, a leader in cloud-based solutions ... A1 funding led by UK-based Eurovestech. Peak Ventures and ... investment round. "We are at a pivotal ... sequencing and seeks new approaches for the diagnosis, treatment ... MD MBA, and CEO of Tute Genomics. "One of ...
Breaking Biology News(10 mins):Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 4Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 2Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 3Tute Genomics Raises $2.3 Million to Scale Up Cloud-Based Genome Analytics and Accelerate Personalized Medicine 2Tute Genomics Raises $2.3 Million to Scale Up Cloud-Based Genome Analytics and Accelerate Personalized Medicine 3
... WI, JUNE 30, 2011 -- Agroforestry, the deliberate placement ... capture substantial amounts of carbon on agricultural lands while ... tools for accurately estimating current and projected carbon values ... an effective carbon-capturing option. Only occupying about 2 to ...
... scientific results from an ambitious voyage led by a group ... San Diego offer a stark view of human pollution and ... been labeled as the "Great Pacific Garbage Patch." Two ... or SEAPLEX, found evidence of plastic waste in more than ...
... HFES invites you to register to attend the 55th ... Red Rock Hotel in Las Vegas! Early bird discounts ... the Registration Information page at http://www.hfes.org/web/HFESMeetings/2011registration.html for ... more. Online registration is available at http://tinyurl.com/3drb8hz . ...
Cached Biology News:Scripps study finds plastic in 9 percent of 'garbage patch' fishes 2Scripps study finds plastic in 9 percent of 'garbage patch' fishes 3HFES 2011 registration is now open 2
(Date:12/24/2014)... NEW YORK , Dec. 23, 2014  NeuroLifeSciences ... of mazindol in children with attention deficit/hyperactivity disorder published ... 2014 . The paper, titled "Pilot ... deficit/hyperactivity disorder" ( Konofal et al, Drug ... 2014 ) shows that mazindol might be an ...
(Date:12/22/2014)... , Dec. 22, 2014 /PRNewswire/ - RepliCel Life ... regenerative medicine company focused on the development of autologous ... out of the University of Calgary in conjunction with ... Carolina, which further validates the company,s ongoing clinical research ... effects of pattern baldness. The paper entitled ...
(Date:12/22/2014)... 2014  ( www.competitivehealth.com ) — Competitive Health is ... review and advocacy service, has signed an agreement to ... discount health services marketplace. 63% of Americans ... they expected to pay. As part of an ongoing ... Savings is pleased to offer medical bill review and ...
(Date:12/22/2014)... Fertility Associates of Memphis has announced a new ... network of more than 20 contributing fertility practices ... access to a national pool of frozen donor ... of Memphis is the only fertility clinic in the ... Dr. William Kutteh , director of Fertility Associates of ...
Breaking Biology Technology:Redefining ADHD: A New Approach & A Shift of Paradigm in ADHD Therapeutics 2Redefining ADHD: A New Approach & A Shift of Paradigm in ADHD Therapeutics 3Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 2Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 3Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 4Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 5WellCard Savings Announces CoPatient Medical Bill Review Service for Members 2Fertility Associates of Memphis Announces Partnership with Donor Egg Bank USA 2Fertility Associates of Memphis Announces Partnership with Donor Egg Bank USA 3
... Program Called ... ... GEN),announced today a new pre-clinical antibody program called HuMax-CD32b(TM).,This fully ... and hematological tumors. HuMax-CD32b may have therapeutic potential,in the treatment ...
... of gallons of hazardous waste resulting from the nations ... southeastern Washington state called Hanford. Beneath this desert ... of thousands of tons of chemicals are captured within ... complex subsurface flow paths. These paths create uncertainties ...
... 3 /Xinhua-PRNewswire/ -- WuXi PharmaTech (NYSE:,WX), China,s premier provider ... that it has promoted Mr. Edward Hu from Executive,Vice ... to joining WuXi PharmaTech in August 2007, Mr. Hu ... Tanox, Inc., a NASDAQ listed,company later acquired by Genentech, ...
Cached Biology Technology:Genmab Announces HuMax-CD32b Pre-Clinical Program 2Genmab Announces HuMax-CD32b Pre-Clinical Program 3Where does stored nuclear waste go? 2WuXi PharmaTech (NYSE: WX) Promotes Edward Hu to COO 2
...
Anti-VDAC (Voltage-Dependent Anion Channel) AVOID FREEZE/THAW CYCLES. Recognizes the porin 31HL protein. Corresponds to mAb 1 in the literature....
This spacer is required to use the Miniature FRENCH Pressure Cell (FA-003) with the Laboratory Press....
... DNase I Amplification Grade ... DNA to oligodeoxyribonucleotides. The ... units/mg. DNAse I Amplification ... and tested for absence ...
Biology Products: