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Rare disease provides clues about enzyme role in arrhythmias
Date:12/11/2008

keep a regular beat, Anderson said.

"The defect causes the channel to close too slowly, and this in turn amplifies CaM kinase II, which in turn can cause disease," he said. "You can't completely block calcium channels because you need some function to initiate heartbeats. Ideally, we would find a way to allow the defective channel to operate but without allowing the CaM kinase II to be over activated."


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Contact: Becky Soglin
becky-soglin@uiowa.edu
319-335-6660
University of Iowa
Source:Eurekalert

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