Navigation Links
Rapid prenatal test for alpha-thalassemia
Date:5/11/2010

Nakornpathom, Thailand Researchers from Mahidol University have developed a rapid, high-throughput screening method for prevention and control of thalassemia. The related report by Munkongdee et al, "Rapid diagnosis of α-thalassemia by melting curve analysis," appears in the May 2010 issue of The Journal of Molecular Diagnostics.

α-Thalassemia is a blood disease caused by a genetic defect in the production of a component of hemoglobin. This disease is more prevalent in areas that either were previously or are currently endemic for malaria, including the Mediterranean and South Asia. Carriers of mutations in α-thalassemia may have some degree of protection against malaria, but children of parents who both carry the mutation α-thalassemia-1 may develop Hb Bart's hydrops fetalis, which results in fetal death in utero or soon after birth.

Prenatal screening and genetic counseling are essential for prevention and control of α-thalassemia. The current diagnostic assay is both labor-intensive and time-consuming. Therefore, researchers led by Dr. Saovaros Svasti of Mahidol University developed a novel, rapid, and reliable assay for the diagnosis of α-thalassemias. This assay has high sensitivity and specificity, rapid turnaround time, and a decreased risk of contamination between samples.

Munkongdee et al suggest that this technique will "allow [for] high throughput screening suitable for prevention and control of thalassemia in the Southeast Asia population."


'/>"/>

Contact: Angela Colmone, Ph.D.
acolmone@asip.org
301-634-7953
American Journal of Pathology
Source:Eurekalert

Page: 1

Related biology news :

1. Rapid response team investigates coral disease outbreak in Kaneohe Bay, Oahu
2. Workshop on R&D for rapid vaccine development and production in Asia/Australia
3. CSHL scientists use next-gen sequencing to rapidly discover genetic cause of devastating disorder
4. Rapid flu testing
5. Trial of new treatment for advanced melanoma shows rapid shrinking of tumors
6. Growing Demand for Rapid Screening and Detection Systems Pushes the European Maritime Security Market, Finds Frost & Sullivan
7. K-State host to workshop on rapid methods to detect microorganisms in food
8. German Research Minister Schavan: Rapid knowledge transfer can safe lives
9. Rapid approach to identify influenza A virus mutations and drug resistance developed
10. HudsonAlpha investigator develops rapid response swine flu test
11. Study finds hemlock trees dying rapidly, affecting forest carbon cycle
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/21/2016)... June 21, 2016 NuData Security announced today ... role of principal product architect and that ... of customer development. Both will report directly to ... The moves reflect NuData,s strategic growth in its ... high customer demand and customer focus values. ...
(Date:6/16/2016)... June 16, 2016 The ... expected to reach USD 1.83 billion by 2024, ... Research, Inc. Technological proliferation and increasing demand in ... expected to drive the market growth. ... The development of advanced multimodal techniques for ...
(Date:6/9/2016)... June 9, 2016  Perkotek an innovation leader in attendance control systems is proud ... work hours, for employers to make sure the right employees are actually signing in, ... ... ... ...
Breaking Biology News(10 mins):
(Date:12/8/2016)...  The Board of Directors of the Pittsburgh ... only pure life sciences investment firm, today ... succession plan developed by the Nominating and Governance Committee ... (Jim) F. Jordan is selected to serve as ... Manzetti , who is elected to the position of ...
(Date:12/8/2016)... ... ... Lajollacooks4u, San Diego’s premier team building events and cooking events company, announced ... and company expansion. , This is largely due to its team building ... people. Ever since, Lajollacooks4u has seen significant demand for its services from organizations across ...
(Date:12/8/2016)... ... December 08, 2016 , ... From wearable devices ... taking over sports. On Thursday, December 15th a panel of entrepreneurs, innovators and ... playing field at a Smart Talk session. Smart Talk will run from 8:30 ...
(Date:12/8/2016)...  Biotheranostics today announced that new data will ... Cancer Index (BCI) in identifying which patients with ... for disease recurrence and might benefit from extended ... advancing the understanding of the value of BCI ... inform decisions related to patient treatment. These data ...
Breaking Biology Technology: