Navigation Links
Rapamycin: Limited anti-aging effects
Date:7/25/2013

er's summary of the findings. "Most aging traits were not affected by rapamycin treatment. Although we did observe positive effects on some aging traits, such as memory impairments and reduced red blood cell counts, our studies showed that similar drug effects are also seen in young mice, indicating that rapamycin did not influence these measures by slowing aging, but rather via other, aging-independent, mechanisms."

The researchers believe that such aging-independent drug effects also underlie rapamycin's effect on lifespan. "We assume that the lifespan of mice is extended because rapamycin inhibits tumor formation. This is a well-known rapamycin effect, which we were able to confirm. Cancer is the leading cause of death in the relevant mouse strains" says the specialist in molecular medicine. "Rapamycin, therefore, seems to have isolated effects on specific life-limiting pathology, but lacks broad effects on aging in mice."

A comprehensive assessment of aging

The research team assessed more than 150 traits, which typically change during the course of aging. These analyses included an assessment of vision, reflexes, cardiovascular function, learning and behavior, immune functions and the integrity of the arterial wall, to just name a few. "Aging is a complex process, which cannot be captured by assessing a single parameter. This is why we analysed a large number of structural and functional signs of aging," explains Ehninger. "The present study is one of the most comprehensive assessments of a putative anti-aging intervention."

The analysis comprised three different age cohorts, in which rapamycin treatment was either initiated in young adulthood, in midlife or late in life. "At the time, the US study showed that rapamycin extends lifespan irrespective of whether the treatment is given to young or aged animals," says the Bonn-based researcher. "We, therefore, chose a study design, in the context of which we also investiga
'/>"/>

Contact: Dr. Dirk Förger
presse@dzne.de
49-228-433-02260
Helmholtz Association of German Research Centres
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Oysters could rebound more quickly with limited fishing and improved habitat
2. Older US-born Mexican-Americans more physically limited than Mexican-American immigrants: Study
3. Most coral reefs are at risk unless climate change is drastically limited
4. Ducks Unlimited Canada and Canadian Light Source partnership to shed light on wetlands
5. Scientists sequence genome of sacred lotus, which likely holds anti-aging secrets
6. Hydrogen sulfide: The next anti-aging agent?
7. Anti-aging elixir for solar cells
8. Canadian girl, 16, invents disease-fighting, anti-aging compound using tree particles
9. Key target responsible for triggering detrimental effects in brain trauma identified
10. Adverse effects of phthalates on ovarian response to IVF
11. Time is of the essence for reducing the long-term effects of iron deficiency
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... 22, 2015   EyeLock, Inc. , a market leader of ... Steve Gerber to the new role of Senior Vice ... leading development of mobile platforms and wearable solutions for EyeLock,s ... innovation in the semiconductor industry to his role at EyeLock, ...
(Date:12/22/2014)... 2014 Holiday Season may be the brightest ever for ... the long anticipated floodgates for consumer biometrics may finally ... phones, tablets, and wearable mobile devices that incorporate biometrics ... with nearly 4.8 billion biometric devices by 2020.   ...
(Date:12/17/2014)... 2014 Research and Markets ( http://www.researchandmarkets.com/research/s6qzt5/samsung_galaxy_s5 ) ... S5 - Home Button Synaptics Fingerprint Sensor Technology Analysis" ... http://photos.prnewswire.com/prnh/20130307/600769 Based on a totally ... for the first time a fingerprint sensor in its ...
Breaking Biology News(10 mins):EyeLock Names Steve Gerber as Senior Vice President of Mobile and Wearables 2First Season of Holiday Shopping with Mobile Biometric Payments Wraps Up With a Present for Biometrics Industry: A Rosy Forecast for More Than 2 Billion Users of 4.8 Billion Mobile Biometric Devices by 2020 2Samsung Galaxy S5 - Home Button Synaptics Fingerprint Sensor Technology Analysis 2
... for splitting water into hydrogen and oxygen, driven by ... today, underpinning the long term potential of hydrogen as ... today are very inefficient and often require additional use ... important to establish new mechanisms by which water splitting ...
... eaten raw, fried and baked it even produces banana beer ... the fruit is only a small percentage of what the plant ... to rot as waste. Now scientists at The University of ... fuel, developing simple methods of producing banana briquettes that could be ...
... Three-day-old broccoli sprouts, a widely available human food, suppressed ... to a report in Cancer Prevention Research , a ... H. pylori infections are one of the most common ... cancer. The cancer protective effects of sulforaphane, a ...
Cached Biology News:Weizmann Institute scientists develop a unique approach for splitting water into hydrogen and oxygen 2Weizmann Institute scientists develop a unique approach for splitting water into hydrogen and oxygen 3Going bananas for sustainable research -- scientists create fuel from African crop waste 2
(Date:12/24/2014)... MA (PRWEB) December 23, 2014 ... is designed to introduce cutting edge communication technology, ... of platform upgrades. This webinar series demonstrates online ... quest to leverage web conferencing’s most innovative and ...
(Date:12/24/2014)... York (PRWEB) December 23, 2014 According to ... Long Island Affiliate of ITRA Global, the national office market ... steady recovery. This is evidenced by the third quarter’s ... stock market. Low energy costs have held inflation down ...
(Date:12/24/2014)... Nashville Fertility Center announced that Dr. George A. ... Reproductive Medicine (ASRM), a leading professional organization committed to advancing ... role as treasurer, Dr. Hill also fills a seat on ... the mission of ASRM. , Dr. Hill has actively ...
(Date:12/24/2014)... 23, 2014 Pipette.com announces their Holiday ... submit their #HolidayInTheLab pictures for a chance to win pipette-themed ... struggling to think of a holiday gift for their beloved ... the ideal holiday presents. The #HolidayInTheLab Contest encourages Pipette.com ...
Breaking Biology Technology:SoundConnect Launches Leading Edge Business Communications Webinar Series 2SoundConnect Launches Leading Edge Business Communications Webinar Series 3ITRA Global Reports Long Island Is Out of Sync With The National Office Market 2ITRA Global Reports Long Island Is Out of Sync With The National Office Market 3Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 2Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 3Major Pipette Distributor Pipette.com Announces their Holiday in the Lab Contest 2
... Novavax, Inc. (Nasdaq: NVAX ) announced today ... company,s Chief Scientific Officer who will report to Dr. ...  Previously, Dr. Glenn was Chief Scientific Officer and founder of ... Johns Hopkins University,s School of Public Health and ...
... 2010 Olivier Bohuon will be,replacing Jean-Pierre Garnier ... , , , ... Olivier Bohuon , 51, was Executive Vice-President of the Abbott,Corporation and President ... Chicago ( $22 billion in sales).,In 2003, he was named ...
... , July 1 United Therapeutics Corporation ... (HKEx: 0950) announced today that they have entered into ... Injection in China .  Remodulin is a subcutaneously ... pulmonary arterial hypertension.  Lee,s Pharmaceutical is a leading Chinese ...
Cached Biology Technology:Novavax Announces Appointment of Dr. Gregory Glenn as Chief Scientific Officer 2Novavax Announces Appointment of Dr. Gregory Glenn as Chief Scientific Officer 3Novavax Announces Appointment of Dr. Gregory Glenn as Chief Scientific Officer 4Olivier Bohuon Joins Pierre Fabre 2United Therapeutics and Lee's Pharmaceutical Sign Remodulin Distribution Agreement for China 2United Therapeutics and Lee's Pharmaceutical Sign Remodulin Distribution Agreement for China 3United Therapeutics and Lee's Pharmaceutical Sign Remodulin Distribution Agreement for China 4United Therapeutics and Lee's Pharmaceutical Sign Remodulin Distribution Agreement for China 5
DITHIOTHREITOL, 150UMOL, 1 EA. Dithiothreitol (DTT), 0.1 M Solution:, *0.1 M solution of DTT in high purity dH2O., *0.2 m filtered., *Storage: -20C. Category: SEQUENASE....
... Varian Cary 50 Microplate Reader ... cost per analysis by extending ... the award-winning Cary 50 instruments. ... to 384 samples in microlitre ...
... Polynucleotide Kinase for labeling of 5' ... acids. In the exchange reaction T4 ... group from DNA to ADP and ... to the free 5' hydroxyl group ...
ImageQuant 400, 1 EA. Category: ImageQuant CCD Imagers....
Biology Products: