Navigation Links
'Rain Man'-like brains mapped at UCSF
Date:2/28/2013

Combining hospital MRIs with the mathematical tool known as network analysis, a group of researchers at UC San Francisco and UC Berkeley have mapped the three-dimensional global connections within the brains of seven adults who have genetic malformations that leave them without the corpus callosum, which connects the left and right sides of the brain.

These "structural connectome" maps, described in the upcoming April 15, 2013 issue of the journal Neuroimage, reveal new details about the condition known as agenesis of the corpus callosum, which is one of the top genetic causes of autism and was part of the mysterious brain physiology of Laurence Kim Peek, the remarkable savant portrayed by Dustin Hoffman in the 1987 movie "Rain Man."

While some people born with agenesis of the corpus callosum are of normal intelligence and do not have any obvious signs of neurologic disease, approximately 40 percent of people with the condition are at high risk for autism. Given this, the work is a step toward finding better ways to image the brains of people with the condition, said Pratik Mukherjee, MD, PhD, a professor of radiology and biomedical imaging at UCSF who was the co-senior author of the research.

Understanding how brain connectivity varies from person to person may help researchers identify imaging biomarkers for autism to help diagnose it and manage care for individuals. Currently autism is diagnosed and assessed based on cognitive tests, such as those involving stacking blocks and looking at pictures on flip cards.

While the new work falls short of a quantitative measure doctors could use instead of cognitive testing, it does offer a proof-of-principle that this novel technique may shed light on neurodevelopment disorders.

"Because you are looking at the whole brain at the network level, you can do new types of analysis to find what's abnormal," Mukherjee said.

The Connection between the Brain Hemi
'/>"/>

Contact: Jason Socrates Bardi
jason.bardi@ucsf.edu
415-502-6397
University of California - San Francisco
Source:Eurekalert  

Page: 1 2

Related biology news :

1. CETS offers new method to help simplify the study of brain pathologies
2. Bioliq pilot plant: Successful operation of high-pressure entrained flow gasification
3. Brown unveils novel wireless brain sensor
4. Bridging the gap: Hope that all meningitis strains will be vaccinated for
5. Ability of brain to protect itself from damage revealed
6. Activation of cortical type 2 cannabinoid receptors ameliorates ischemic brain injury
7. Engineering control theory helps create dynamic brain models
8. New study shows how seals sleep with only half their brain at a time
9. Shedding new light on infant brain development
10. Brain prostheses create a sense of touch
11. Teaching the brain to speak again
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
'Rain Man'-like brains mapped at UCSF
(Date:6/24/2015)... 2015 The biologics safety testing market is ... the market include growth of the pharmaceutical and biological ... Over the years, the number of drug approvals in ... the FDA approved 225 drug applications and Health Canada ... Europe accounted for 3,822 of the pharmaceutical ...
(Date:6/23/2015)...   MedNet Solutions , an innovative SaaS-based ... of clinical research, is pleased to announce that ... company,s intuitive, flexible and affordable cloud-based eClinical technology ... Award by the American Business Awards (SM) ... The American Business Awards are considered the nation,s ...
(Date:6/18/2015)... , June 18, 2015 NXT-ID, Inc. (NASDAQ: ... company focused on the growing mobile commerce market announces that ... featured segment on "Money on the Mark", scheduled to air ... June 20 th . The ... be from 7:00 to 8:00pm EST. NXT-ID, Inc.,s CEO ...
Breaking Biology News(10 mins):Biological Safety Testing Market by Application, Product, & Test - Global Forecast to 2019 2Biological Safety Testing Market by Application, Product, & Test - Global Forecast to 2019 3Biological Safety Testing Market by Application, Product, & Test - Global Forecast to 2019 4MedNet Solutions' iMedNet eClinical Wins Silver Stevie Award 2NXT-ID, Inc.'s CEO Gino Pereira Talks About the Wocket Smart Wallet on WABC Radio, New York City, June 20th 2NXT-ID, Inc.'s CEO Gino Pereira Talks About the Wocket Smart Wallet on WABC Radio, New York City, June 20th 3
... mass extinction of marine life in our oceans during prehistoric ... an extinction again because of high levels of greenhouse gases, ... from the University of Adelaide (School of Earth ... University (Civil Engineering and Geosciences) have been studying ,greenhouse ...
... Scientists at UC Santa Barbara have developed new methods for ... ecosystems at unprecedented spatial and temporal scales. The scientists ... of giant kelp canopies taken by the Landsat 5 Thematic ... the May 16 issue of Marine Ecology Progress Series. ...
... Service and the Southern Group of State Foresters released the ... Tuesday, May 17, which identifies areas forest managers will focus ... According to the report, urbanization, bioenergy use, weather patterns, ... South,s forests between the years 2010 and 2060. About ...
Cached Biology News:Greenhouse ocean study offers warning for future 2UCSB scientists track environmental influences on giant kelp with help from satellite data 2UCSB scientists track environmental influences on giant kelp with help from satellite data 3Forest Service unveils first comprehensive forecast on southern forests 2Forest Service unveils first comprehensive forecast on southern forests 3
(Date:6/30/2015)... , July 1, 2015 R-Japan Co.,Ltd. obtained ... the Safety of Regenerative Medicine from the Ministry of Health, ... June 29, 2015. The fact that R- ... facility through the auditing from Pharmaceuticals and Medical Devices Agency ... application, allows it to provide stem cell manufacturing service to ...
(Date:6/30/2015)... 30, 2015 /PRNewswire/ - Resverlogix Corp. ("Resverlogix") (TSX:RVX) ... of Resverlogix have approved the resolutions relating to: ... of 5,600,000 units at a price of $2.67 ... being comprised of one common share and 0.075358 ... approximately CAD$15 million; and (ii) the amendment to ...
(Date:6/30/2015)... , June 30, 2015  NASA astronaut Kjell ... next month on his first mission to the International ... from 8 to 9 a.m. EDT Tuesday, July 7. ... in Star City, Russia . The interviews ... NASA Television highlighting his mission training. To schedule ...
(Date:6/30/2015)... , June 30, 2015  Today, Americord Registry, one ... announced Andrew Horne , a partner at Kirkland & ... Logo - http://photos.prnewswire.com/prnh/20150630/226958LOGO   ... Americord,s Advisory Board," says Martin Smithmyer , CEO of ... his legal career that will assist Americord,s growth and vision." ...
Breaking Biology Technology:R-Japan Obtained Autologous Stem Cell Manufacturing License from the Ministry of Health, Labour and Welfare 2Resverlogix Corp. Shareholders Approve Matters Relating to Licensing and Equity Arrangement 2Resverlogix Corp. Shareholders Approve Matters Relating to Licensing and Equity Arrangement 3NASA Astronaut Preps for First Space Station Mission, Available for Media Interviews 2Americord Registry Announces Andrew Horne as Advisory Board Member 2
... fusions in lysates of the yeast Saccharomyces cerevisiae using the ... , Paul Gavin # and Mark ... Ph.D* , # Department of Biochemistry ... Victoria 3800, Australia , * Technical assistance: Varian ...
... Purpose , ... chiral compounds using the API 3000 LC/MS/MS System. , ... In recent years, pharmaceutical companies have placed ... chiral center. Isomerspecific pharmaceuticals often exhibit increased potency, higher bioavailability and ...
... Abstract , ... total RNA from biological sources such as cultured cells. These techniques ... and produce a highly pure product, free of PCR inhibitors, that ... These new techniques respond to the demand for high-quality, highthroughput ...
Cached Biology Technology: Monitoring fluorescence resonance energy transfer (FRET) between GFP, fusions in lysates of the yeast Saccharomyces cerevisiae using the , Varian, Cary Eclipse 2 Monitoring fluorescence resonance energy transfer (FRET) between GFP, fusions in lysates of the yeast Saccharomyces cerevisiae using the , Varian, Cary Eclipse 3 Monitoring fluorescence resonance energy transfer (FRET) between GFP, fusions in lysates of the yeast Saccharomyces cerevisiae using the , Varian, Cary Eclipse 4Separation and Quantitation of R and S Enantiomers using Normal Phase Chromatography on an API 3000 LC/MS/MS System 2Separation and Quantitation of R and S Enantiomers using Normal Phase Chromatography on an API 3000 LC/MS/MS System 3Total RNA Purification from Cultured Cells Using the ABI PRISM 6700 Automated Nucleic Acid Workstation and Total RNA Lysis Reagents 2Total RNA Purification from Cultured Cells Using the ABI PRISM 6700 Automated Nucleic Acid Workstation and Total RNA Lysis Reagents 3Total RNA Purification from Cultured Cells Using the ABI PRISM 6700 Automated Nucleic Acid Workstation and Total RNA Lysis Reagents 4Total RNA Purification from Cultured Cells Using the ABI PRISM 6700 Automated Nucleic Acid Workstation and Total RNA Lysis Reagents 5Total RNA Purification from Cultured Cells Using the ABI PRISM 6700 Automated Nucleic Acid Workstation and Total RNA Lysis Reagents 6
HRP Monoclonal-Goat Diluent - 5X Concentrate, 25 mL...
... gel electrophoresis into an automated, high-throughput operation ... pre-cast system is ideal for analyzing multiple ... more. Fully automated, robot-compatible, and ready to ... makes your high-throughput screening assignments as easy ...
...
Fluorescence Preserving Media, 100 mL...
Biology Products: