Navigation Links
Race could be a factor in head and neck cancer survival rates, MU researchers find
Date:6/5/2014

COLUMBIA, Mo. The national survival rates for African-Americans diagnosed with head and neck cancer have not improved in the last 40 years despite advances in the treatment and management of the disease, University of Missouri School of Medicine researchers have found in a new study.

More than 52,000 men and women in the United States currently are living with head and neck cancer. Using data from the National Cancer Institute's Surveillance, Epidemiology and Ends Results (SEER) program, MU researchers under the guidance of Mosharraf Hossain, M.D., assistant professor in the MU School of Medicine's Division of Hematology and Oncology and physician with Ellis Fischel Cancer Center in Columbia, Missouri, studied the survival trend of five ethnic groups over the last 40 years. The researchers found that despite advances in treatment options, the prognosis for African-Americans with head and neck cancer has not improved.

"This study shows that we've made good progress in treating head and neck cancer over the last 37 years, and survival has dramatically improved," said Shahzad Raza, M.D., a post-doctoral fellow in the MU School of Medicine's Division of Hematology and Oncology and lead investigator of the study. "However, we found no change in the survival or prognosis for African-Americans in the last four decades."

By analyzing data collected from 1973 to 2010 on 247,310 head and neck cancer patients nationwide, the researchers found that the incidence of head and neck cancer was higher in African-Americans than in Caucasians, Hispanics, Asians and Pacific Islanders, or Asian-Indian and Alaskan natives. All of these ethnic groups except African-Americans showed improved five-year survival rates over a 40-year period. African-Americans had a significantly decreased five-year overall survival rate of 41.8 percent, compared with 60.8 percent survival for Caucasians, 59.3 percent survival for Hispanics, 62 percent survival for Asians and Pacific Islanders, and 50.2 percent survival for Asian-Indian and Alaskan natives.

"One commonly held theory is that socioeconomic status, access to health care and the stage in which the cancer is diagnosed all play a major role in the survival rates of African-Americans with head and neck cancer," Raza said. "However, these factors are not completely accurate predictors of a patient's prognosis."

Raza said the treatment for head and neck cancer depends on the location of the tumor, the stage of the cancer, and the patient's age and overall health. Treatments can include surgery, radiation therapy, chemotherapy, targeted therapy or a combination of treatment options.

The researchers suggest that inherent genetic factors in African-Americans may make some tumors resistant to treatments. However, more research needs to be done on the subject of survival disparity in patients with head and neck cancer.

"This research shows there is an urgent need for a national trial on head and neck cancer within the African-American community to evaluate new forms of treatment and biogenetic markers to learn why this ethnic group has decreased survival rates," Raza said.


'/>"/>

Contact: Derek Thompson
thompsonder@health.missouri.edu
573-882-3323
University of Missouri-Columbia
Source:Eurekalert  

Related biology news :

1. Researchers shut down a SARS cloaking system; findings could lead to SARS, MERS vaccines
2. Molecular scaffold could hold key to new dementia treatments
3. In Africa, STI testing could boost HIV prevention
4. New sensor could light the way forward in low-cost medical imaging
5. New insights into premature ejaculation could lead to better diagnosis and treatment
6. Mars mineral could be linked to microbes
7. Bacteria in urine could contribute to overactive bladder
8. 3-D map of enzyme completed by MU scientists could lead to more effective drugs
9. Dangerous nitrogen pollution could be halved
10. Ability to isolate and grow breast tissue stem cells could speed cancer research
11. Space Station research shows that hardy little space travelers could colonize Mars
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Race could be a factor in head and neck cancer survival rates, MU researchers find
(Date:3/23/2017)... , March 23, 2017 The report "Gesture Recognition ... Biometric), Industry, and Geography - Global Forecast to 2022", published by MarketsandMarkets, the ... a CAGR of 29.63% between 2017 and 2022. ... ... ...
(Date:3/22/2017)... 21, 2017 Vigilant Solutions , a ... enforcement agencies, announced today the appointment of retired FBI ... public safety business development. Mr. Sheridan brings ... including a focus on the aviation transportation sector, to ... position, Mr. Sheridan served as the Aviation Liaison Agent ...
(Date:3/13/2017)... Future of security: Biometric Face Matching software  ... ... enables to match face pictures against each other or against large databases. The ... ... fastest software for biometric Face Matching on the market. The speed is at ...
Breaking Biology News(10 mins):
(Date:3/23/2017)... , March 23, 2017  Agriculture technology company ... A financing and note conversion to commercialize its Cool ... is focused on developing products that are simultaneously profitable ... million in the last 18 months. This latest round ... Bridge Venture Partners. The company,s primary ...
(Date:3/22/2017)... -- Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN), today announced a major ... and GSK to generate genetic sequence data from the 500,000 ... enable researchers to gain valuable insights to support advances in ... serious and life threatening diseases. ... Genetic evidence has revolutionized scientific ...
(Date:3/22/2017)... March 22, 2017  UBM and the Massachusetts ... their extended partnership and the third annual Massachusetts Medtech ... the 21 st Annual MassMEDIC Conference held ... May 3-4, 2017. MassMEDIC will ... (ADVAMED) President and CEO, Scott Whitaker , ...
(Date:3/22/2017)... March 22, 2017   iSpecimen ®, the ... Doctors Pathology Service (DPS), a full-service anatomic ... the United States , has joined a ... Information Network (DHIN) to make human biospecimens and ... The novel program, announced in 2015 as a collaboration ...
Breaking Biology Technology: