Navigation Links
RTS,S malaria candidate vaccine reduces malaria by approximately one-third in African infants
Date:11/9/2012

International African Vaccinology Conference, Cape Town, South AfricaResults from a pivotal, large-scale Phase III trial, published online today in the New England Journal of Medicine, show that the RTS,S malaria vaccine candidate can help protect African infants against malaria. When compared to immunization with a control vaccine, infants (aged 6-12 weeks at first vaccination) vaccinated with RTS,S had one-third fewer episodes of both clinical and severe malaria and had similar reactions to the injection. In this trial, RTS,S demonstrated an acceptable safety and tolerability profile.

Eleven African research centres in seven African countries [1] are conducting this trial, together with GlaxoSmithKline (GSK) and the PATH Malaria Vaccine Initiative (MVI), with grant funding from the Bill & Melinda Gates Foundation to MVI.

Dr. Salim Abdulla, a principal investigator for the trial from the Ifakara Health Institute, Tanzania, said: "We've made significant progress in recent years in our battle against malaria, but the disease still kills 655,000 people a yearmainly children under five in sub-Saharan Africa. An effective malaria vaccine would be a welcome addition to our tool kit, and we've been working toward this goal with this RTS,S trial. This study indicates that RTS,S can help to protect young babies against malaria. Importantly, we observed that it provided this protection in addition to the widespread use of bed nets by the trial participants."

Efficacy

When administered along with standard childhood vaccines,[2] the efficacy of RTS,S in infants aged 6 to 12 weeks (at first vaccination) against clinical and severe malaria was 31% and 37%,[3] respectively, over 12 months of follow-up after the third vaccine dose.[4] Insecticide-treated bed nets were used by 86% of the trial participants, which demonstrated that RTS,S provided protection beyond existing malaria control interventions. The efficacy observed with RT
'/>"/>

Contact: Preeti Singh
psingh@burnesscommunications.com
301-280-5722
Burness Communications
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Notre Dame researchers using novel method to combat malaria drug resistance
2. Scientists find Achilles heel in life-threatening malaria parasites
3. Drug could reverse scourge of cerebral malaria for survivors
4. Game on! UCLA researchers use online crowd-sourcing to diagnose malaria
5. African scientist, designer partner to fashion anti-malaria garment that wards off bugs
6. Considerable prevalence of both malaria, STIs exist among pregnant women in sub-Saharan Africa
7. New discoveries about severe malaria
8. New book tells story of 10-year-old malaria project
9. MMV develops framework to assess risk of resistance for antimalarial compounds
10. African research identifies strong candidate for possible single-dose malaria cure
11. WSU/USDA scientist creates test, treatment for malaria-like sickness in horses
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/24/2015)... Research and Markets ( http://www.researchandmarkets.com/research/sxwl43/global_2d_gesture ... "Global 2D Gesture Recognition Market 2015-2019" report ... forecast the Global 2D Gesture Recognition market to ... period 2014-2019 The increased demand for ... of the major trends in the market. The ...
(Date:2/12/2015)...   MedNet Solutions , a global life ... systems, has recently bolstered its iMedNet™ ... iMedNet as the eClinical solution of ... consultants.  Building on the Program,s existing benefits (including ... co-marketing opportunities), MedNet,s new and improved program provides ...
(Date:2/5/2015)... North Carolina , 5. Februar 2015 ... Jahr als spezialisiertes Logistikunternehmen und hat eine ... einzige klinische Logistikfirma (Clinical Logistics Organization – ... der neuen Kampagne lautet First , ... Foto: http://photos.prnewswire.com/prnh/20150205/173753 ...
Breaking Biology News(10 mins):Global 2D Gesture Recognition Market 2015-2019 with Cognitec Systems, CogniVue, eyeSight Mobile Technologies & PointGrab Dominating 2MedNet Solutions Announces Key Enhancements To Its iMedNet Partner Program 2Marken startet Kampagne mit Patienten im Mittelpunkt 2Marken startet Kampagne mit Patienten im Mittelpunkt 3
... , WALL, N.J., Dec. 3 ... in wireless public safety and finger-based biometric identification solutions, ... Special Shareholder Meeting held today approved the sale of ... Inc. Of the shares voted, 98.6% were cast in ...
... Preliminary Press Conference Topics Last Call! Press ... Attention PIOs: Sending Press Releases to Fall meeting ... News Media registration information News Media Registration ... coming For important information regarding visas ...
... Have you ever felt overly upset by a social ... Scientists have long known that opium-like painkillers, called opioids, ... emotional stress. Now, a new study reviewed by Faculty of ... in the gene for the opioid receptor can determine the ...
Cached Biology News:BIO-key(R) Shareholders Overwhelmingly Approve Sale of Law Enforcement Division 2BIO-key(R) Shareholders Overwhelmingly Approve Sale of Law Enforcement Division 3AGU fall meeting: Preliminary press conference topics, press pre-registration deadline 2AGU fall meeting: Preliminary press conference topics, press pre-registration deadline 3AGU fall meeting: Preliminary press conference topics, press pre-registration deadline 4AGU fall meeting: Preliminary press conference topics, press pre-registration deadline 5AGU fall meeting: Preliminary press conference topics, press pre-registration deadline 6
(Date:2/27/2015)... SUMMERLAND, British Columbia , Feb. 27, 2015 ... ), a leader in synthetic biology, today announced it ... Fruits (OSF), the pioneering agricultural company behind the ... non-browning apple. Through the acquisition, Intrexon expands its food ... appetizing and convenient for consumers while providing economic benefit ...
(Date:2/27/2015)... Immunovaccine Inc. (“Immunovaccine”) (TSX: IMV), ... announced that the U.S. Food and Drug Administration ... and Phase I clinical trials of the DPX-Anthrax ... co-development agreement signed with Gilead Life Sciences. The ... the DPX-Survivac. , “We have been in talks ...
(Date:2/27/2015)... February 27, 2015 FamilyFarms Group is ... Manager of State Line Farms, received the 2015 Tomorrow’s ... producer, under the age of 35, who has demonstrated ... an honor to win the Tomorrow's Top Producer Horizon ... won the Top Producer Award and learning from their ...
(Date:2/26/2015)... NEW YORK , Feb. 26, 2015 ... commenced Factual Stock Report coverage on MabVax Therapeutics ... Inc. (MBVX) is a clinical stage biotechnology company focused ... address unmet medical needs in the treatment of cancer. ... products based on the protective immune responses generated by ...
Breaking Biology Technology:Intrexon to Acquire Okanagan Specialty Fruits 2Intrexon to Acquire Okanagan Specialty Fruits 3Intrexon to Acquire Okanagan Specialty Fruits 4Immunovaccine Inc. (TSX: IMV) receives Fast Track and Phase I trial approval for Ebola and Anthrax vaccine programs, signs co-development agreement with Gilead Sciences 2Immunovaccine Inc. (TSX: IMV) receives Fast Track and Phase I trial approval for Ebola and Anthrax vaccine programs, signs co-development agreement with Gilead Sciences 3Matt Sims Receives the 2015 Tomorrow’s Top Producer Horizon Award 2S&P Capital IQ Initiates Coverage on MabVax Therapeutics Holdings Inc. in S&P Capital IQ Factual Stock Reports 2S&P Capital IQ Initiates Coverage on MabVax Therapeutics Holdings Inc. in S&P Capital IQ Factual Stock Reports 3S&P Capital IQ Initiates Coverage on MabVax Therapeutics Holdings Inc. in S&P Capital IQ Factual Stock Reports 4S&P Capital IQ Initiates Coverage on MabVax Therapeutics Holdings Inc. in S&P Capital IQ Factual Stock Reports 5
... advanced energy research , , MONTREAL, July 7 ... technology company, today announced that it will jointly form ... Edmonton and the Alberta Energy Research Institute (AERI). , ... demonstration of novel catalytic conversion processes to produce advanced ...
... following letter is being released by CEL-SCI Corporation (NYSE Amex: ... , , Recently we have been hearing a great deal about the ... this is no big deal since it does not seem that serious and, ... both counts! In this letter I will show you where in the ...
... REDWOOD CITY, Calif., July 7 OncoMed Pharmaceuticals, Inc., ... cancer stem cells, today announced the appointment of Sunil ... Development. In this new position, Mr. Patel will ... directly to Paul Hastings, OncoMed,s President and Chief Executive ...
Cached Biology Technology:Enerkem Announces World-Class Advanced Energy Research Center in Edmonton, Alberta, Canada 2Enerkem Announces World-Class Advanced Energy Research Center in Edmonton, Alberta, Canada 3CEL-SCI Corporation Releases Letter to Shareholders 2CEL-SCI Corporation Releases Letter to Shareholders 3CEL-SCI Corporation Releases Letter to Shareholders 4CEL-SCI Corporation Releases Letter to Shareholders 5CEL-SCI Corporation Releases Letter to Shareholders 6CEL-SCI Corporation Releases Letter to Shareholders 7OncoMed Pharmaceuticals Appoints Sunil Patel Senior Vice President, Corporate Development 2
... product contains 5 ml of DETACHaBEAD Mouse ... mouse CD4+ T cells from Dynabeads Mouse ... CD4+ T cells from Dynabeads Mouse CD4 ... are suitable for any downstream application including ...
Porcine IFN-gamma ELISpot Development Module...
...
Request Info...
Biology Products: