Navigation Links
RSV may hide in the lungs, lead to asthma, UT Southwestern researchers report
Date:10/21/2008

DALLAS Oct. 21, 2008 Conventional wisdom has been that respiratory syncytial virus (RSV) a common virus that causes infection in the lungs comes and goes in children without any long lasting impact.

A study conducted in mice by UT Southwestern Medical Center researchers, however, suggests that RSV may hide in the lungs even after other symptoms abate, ultimately resurfacing to cause recurrent wheezing and chronic airway disease.

"This research suggests that there's a potential new mechanism for asthma related to viral infections in children that could be associated with RSV," said Dr. Asuncion Mejias, assistant professor of pediatrics at UT Southwestern and senior author of a study available online and in the Nov. 15 issue of the Journal of Infectious Diseases. "These findings could aid in the development of preventive and therapeutic interventions for children with recurrent wheezing due to a virus such as RSV."

RSV is the leading cause of viral respiratory infections and hospitalizations in infants and children worldwide. Half of all babies develop an RSV infection within the first year of life and practically all have had at least one RSV infection by age 3, said Dr. Octavio Ramilo, professor of pediatrics at UT Southwestern and study co-author. About 3 percent to 10 percent of infants with RSV infections develop severe bronchitis and require hospitalization.

Most children recover within a week, but RSV can cause repeated infections throughout life. There is currently no vaccine available.

Dr. Ramilo said the team's findings contradict the current thinking that ribonucleic acid viruses like RSV are easily destroyed. "Whether RSV persists in children remains to be seen, but the fact that the virus persists in mice is amazingly powerful," he said.

The most striking finding, Dr. Mejias said, is that the amount of virus detected in the lungs of the mice directly correlates with the severity
'/>"/>

Contact: Kristen Holland Shear
kristen.hollandshear@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. UT Southwestern researchers identify hundreds of genes controlling female fertility
2. BMI criteria for obesity surgery should be lowered, UT Southwestern researcher suggests
3. UT Southwestern secures $5 million NIH grant for lupus research
4. UT Southwestern scientist honored among best in Texas research
5. Stem-cell transplantation improves muscles in MD animal model, UT Southwestern researchers report
6. NIH awards $6.5 million grant to UT Southwestern to develop new antibiotic
7. UT Southwesterns Mangelsdorf elected to National Academy of Sciences
8. Gene mutations in mice mimic human-like sleep disorder, UT Southwestern researchers find
9. Mouse model developed at UT Southwestern mimics hyperglycemia, aids in diabetes research
10. Geology and biology meet in the history of US southwestern desert surface waters
11. UT Southwestern researchers create molecule that nudges nerve stem cells to mature
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... Biologically Inspired Engineering at Harvard University today announced ... by a newly formed private company to accelerate ... products. The announcement follows a worldwide ... (OTD) and the start-up Emulate Inc., relating to ... platform. , "This is a big win ...
(Date:7/27/2014)... largest prevalence studies to date, researchers from the U.K. ... the hepatitis C virus (HCV). Findings published in Hepatology, ... of Liver Diseases, indicate that genotype 1 is the ... of which one-third reside in East Asia. Genotype 3, ... most prevalent, followed by genotypes 2, 4, 6, and ...
(Date:7/27/2014)... single computer cannot always find the solution a user ... cluster of computers that analyze a massive data set ... history to present you with targeted ads, and how ... movie. But big data is about more than just ... are generating unprecedented quantities of information. That data may ...
Breaking Biology News(10 mins):Wyss Institute's technology translation engine launches 'Organs-on-Chips' company 2Wyss Institute's technology translation engine launches 'Organs-on-Chips' company 3Hepatitis C virus genotype 1 is most prevalent worldwide 2New tools help neuroscientists analyze 'big data' 2New tools help neuroscientists analyze 'big data' 3New tools help neuroscientists analyze 'big data' 4New tools help neuroscientists analyze 'big data' 5
... San Diego have identified a potential red tide killer. ... accumulate rapidly in dense concentrations have been on the ... dollars in worldwide losses to fisheries and beach tourism ... referred to as harmful algal blooms, remain unpredictable in ...
... Using classroom, hands-on activities can help instructors to ... Despite its importance, the diversity in soil microbes ... natural resource classrooms composed primarily of undergraduates who ... the candy comes into play. , Stephanie ...
... at City of Hope and the California Department of ... detect botulinum neurotoxin. The toxin is one of the ... and is considered a major potential bioterrorism threat agent. ... the online journal PLoS ONE ( http://www.plosone.org/doi/pone.0002041 ). ...
Cached Biology News:Scripps Oceanography Research pegs ID of red tide killer 2Scripps Oceanography Research pegs ID of red tide killer 3The sweet world of soil microbiology 2Researchers develop new ultrasensitive assay to detect most poisonous substance known 2
(Date:7/28/2014)... 28, 2014  David Hardison, Ph.D., vice president ... , has been elected chairman of the board ... non-profit working to establish common protocols around the ... relates to electronic health records. ... collaborating with organizations across the research and health ...
(Date:7/28/2014)... (PRWEB) July 28, 2014 Appistry, ... services that bring the power of genomics to next-generation ... Appistry Pipeline Challenge . , Two Appistry ... of the National Center for Genome Resources, and Mr. ... and Clinics of Kansas City. Rounding out the panel ...
(Date:7/28/2014)... -- InterMune, Inc. (NASDAQ: ITMN ) today announced ... results at the close of the U.S. markets on ... will be hosted by InterMune at 4:30 p.m. Eastern ... others may participate in the conference call by dialing ... of the webcast and teleconference will be available on ...
(Date:7/28/2014)... The National Model Aviation Museum, located ... pleased to announce that it has been granted full ... United States Air Force. , The certification is the ... this spring with an on-site inspection by Sarah Sessions, ... The National Museum of the United States Air ...
Breaking Biology Technology:ConvergeHEALTH by Deloitte's David Hardison Named Chairman of the Clinical Data Interchange Standards Consortium 2ConvergeHEALTH by Deloitte's David Hardison Named Chairman of the Clinical Data Interchange Standards Consortium 3Appistry Names Industry Experts from the National Center for Genome Resources and Mercy Children's, Kansas City, to Judge Pipeline Challenge Competition 2InterMune to Release Second Quarter Financial Results on August 6 2AMA’s National Model Aviation Museum Granted Full Civilian Museum Certification by the National Museum of the United States Air Force 2
... FRANCISCO, March 7, 2012  More than 1,100 leaders from ... Francisco for the two-day conference CALBIO2012: Driven by Patients ... patient access to new treatments through partnering and collaborative ... BIOCOM are organizing a statewide meeting for California,s life ...
... Palatin Technologies, Inc. (NYSE Amex: PTN ) ... ROTH OC Growth Stock Conference on Tuesday, March 13, 2012, ... at the Ritz Carlton Laguna Niguel in Dana Point, CA. ... Officer of Palatin Technologies, will provide an update on Palatin,s ...
...  Synthetic Biologics, Inc.  (NYSE Amex: SYN ), ... medicines for serious illnesses, announced today that Jeff Riley, ... ROTH Capital Partners 24th Annual Growth Stock Conference. The ... Ritz Carlton in Dana Point, CA. Mr. Riley will ...
Cached Biology Technology:First Statewide Biotech Meeting Focuses on Patient Access, Innovation 2Synthetic Biologics to Present at ROTH Annual Growth Stock Conference 2
MOUSE ANTI BOVINE TROPONIN I...
NORMAL DONOR DONKEY SERUM...
This BioSolution package is excellent for doing fluorescence thermal melt experiments on nucleic acids, studies involving biomolecular interactions, protein folding experiments, and more!...
acridine orange 10-nonyl bromide (nonyl acridine orange)...
Biology Products: