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RNA emerges from DNA's shadow
Date:7/10/2008

tween gene expression and nuclear structure that must have played out through evolutionary history. Another point to emerge from Proudfoot's presentation was how some genes are expressed more efficiently for a different reason, because the section of DNA containing their sequence is coiled locally into a loop, rather than as a branch. Quite simply, this speeds up the transcription process of reading the gene because the enzyme concerned, RNA Polymerase, can just keep on encircling the loop. As Proudfoot explained, this is relevant for quality control as well. "They may afford quality control by "telling" the polymerase it is transcribing a bona fide gene, with a proper beginning and end," said Proudfoot. "Otherwise the polymerase may have initiated erroneously." The existence of a DNA ring makes it easier to identify the sequence corresponding to a gene, and transcribe it correctly.


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Contact: Angela Michiko Hama
mhama@esf.org
0033-388-762-149
European Science Foundation
Source:Eurekalert

Page: 1 2 3

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