Navigation Links
RNA emerges from DNA's shadow
Date:7/10/2008

serious disorders caused by deleterious mutations in specific genes, as opposed to problems with the RNA itself. Jacobson also presented one of the most exciting developments, a molecule that overcomes a common deficiency in genes that prevents their being read right up to the end of their sequence during transcription. Jacobson pointed out that there are about 2400 human genetic disorders resulting from mutations that cause genes to be incompletely read, including cystic fibrosis and muscular dystrophy. A drug based on the molecule is now entering trials that could lead to it becoming generally available. Results so far indicate dramatic improvements in both cystic fibrosis and muscular dystrophy sufferers, although it is only suitable for those disorders caused by the presence of a premature stop sign in a gene sequence, as a result of a mutation. It does though highlight the huge therapeutic potential of the research into RNA and its quality control.

Significant progress has been made in different aspects of RNA research over the last decade or more, leading to the current situation where many groups are working on different aspects of the problem. The challenge being met by the ESF's RNAQuality Programme is to bring these groups together, and make Europe a much greater force in the field, according to Jim Anderson, from Marquette University's Department of Biological Sciences in the US.

Another important aspect of RNA research lies in the interaction between DNA transcription, and the physical structure both of the membrane-bound cell nucleus and the genome coiled within it. Genes are transcribed within the nucleus and the resulting RNA molecules then emerge through small holes that are connected to the genome by proteins called nuclear pore complexes. In one of the presentations, Nick Proudfoot from Oxford University in the UK explained how some genes are enhanced by being close to the nuclear pore complex, indicating a close relationship be
'/>"/>

Contact: Angela Michiko Hama
mhama@esf.org
0033-388-762-149
European Science Foundation
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Black carbon pollution emerges as major player in global warming
2. Giant ocean eddy shadows Sydney
3. DNA replication behavior in complex organisms may foreshadow leaps in genomic discoveries
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... 2014 Researchers have pioneered a revolutionary new ... technology, called Virtual Finger, allows scientists to move ... and synapses using the flat surface of their ... imaging studies orders of magnitude more efficient, saving ... across many areas of experimental biology. The software ...
(Date:7/11/2014)... type 1 can inhibit voltage-gated calcium channel, ... release. However, some scholars demonstrated that cannabinoid ... influx and increase neurotransmitter release. Dr. Yi ... to Tongji Medical College, Huazhong University of ... voltage-clamp and calcium imaging in cultured trigeminal ...
(Date:7/10/2014)... , June 27, 2014  The American Academy ... Institute of Standards and Technology (NIST) and the ... academic research and forensic science expert members to ... is an element of the NIST,s Organization of ... among the first appointments made to the new ...
Breaking Biology News(10 mins):Virtual finger enables scientists to navigate and analyze complex 3D images 2Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 2Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 3
... Ore. -- New research has found that if you want ... or other cruciferous vegetables, you need to eat the real ... absorbed and of far less value if taken as a ... Pauling Institute at Oregon State University, is one of the ...
... has awarded UC Santa Barbara up to $15 million ... shape the future of technology in areas that will ... educate future scientists and engineers and advance the discovery ... novel polymers to next-generation microelectronics. The pioneering institute ...
... them, and although they could be effective in theory, antivirulence ... to be published in the online journal mBio ... to fight infection while avoiding the pitfalls of drug resistance. ... growth of pathogens, but antivirulence drugs prevent disease by ...
Cached Biology News:Health benefits of broccoli require the whole food, not supplements 2Health benefits of broccoli require the whole food, not supplements 3UCSB awarded $15 million by Dow to establish collaborative institute for materials research and education 2UCSB awarded $15 million by Dow to establish collaborative institute for materials research and education 3Can antivirulence drugs stop infections without causing resistance? 2
(Date:7/11/2014)... Cayenne Medical, Inc., a privately held ... tissue reconstruction segment, announced the worldwide launch of ... the shoulder and extremities. The SureLock System provides ... method. The unique delivery eliminates manual tensioning that ... anchor displacement (also commonly know as anchor “creep”). ...
(Date:7/10/2014)... (PRWEB) July 10, 2014 Understanding the ... channel-expressing cell lines, and the gap that currently exists ... that expand its industry-leading portfolio of validated ion channel ... ion channel-expressing cell lines, as ion channels control many ... control this activity creates the potential to treat a ...
(Date:7/10/2014)... Los Angeles, CA (PRWEB) July 10, 2014 ... Analytical and Bioanalytical techniques during 18-20 August, 2014 at ... to critically review the recent developments in Analytical & ... across the globe. , Speaking on this occasion, Dr. ... that Analytica Acta conference is a remarkable one ...
(Date:7/10/2014)... July 10, 2014 On July ... Medvedev , presented Russia,s first ... . The Company is developing a unique project called ... BIOCAD develops a number of innovative drugs based on ... The ceremony took place at the International Exhibition "Innoprom ...
Breaking Biology Technology:Cayenne Medical Launches SureLock™ All-Suture Anchor System for Shoulder and Extremity Surgery 2Cayenne Medical Launches SureLock™ All-Suture Anchor System for Shoulder and Extremity Surgery 3Leader in Ion Channel Research Announces Newly Validated and Re-Engineered Cells 2Leader in Ion Channel Research Announces Newly Validated and Re-Engineered Cells 3A Critical Review of Analytical Techniques for Improved Living Standards 2A Critical Review of Analytical Techniques for Improved Living Standards 3A Critical Review of Analytical Techniques for Improved Living Standards 4Dmitry Medvedev Presented BIOCAD the First National "Industry" Award 2
... a bioMerieux company that develops innovative oncology diagnostic tests ... from a clinical study evaluating the company,s Breast Cancer ... the study were presented at the 33rd Annual CTRC-AACR ... The company also announced that the Breast Cancer Index ...
... 2010 Pfizer Inc. (NYSE: PFE ) ... it is voluntarily withdrawing Thelin® (sitaxentan) for the treatment ... is approved (the European Union, Canada and Australia).  In ... (Logo: http://photos.prnewswire.com/prnh/20100416/PFIZERLOGO) Pfizer,s decision ...
... (Dec. 9, 2010) -- Nanotechnologists, marine biologists and signal-processing ... Woods Hole, Mass., and other U.S. universities have won ... Research to unlock the secrets of nature,s best camouflage ... emulate some of the elegant skin colors and patterns ...
Cached Biology Technology:bioTheranostics' Breast Cancer Index(SM) Predicts Risk for Late Recurrence in Early Stage ER-Positive Breast Cancer Patients 2bioTheranostics' Breast Cancer Index(SM) Predicts Risk for Late Recurrence in Early Stage ER-Positive Breast Cancer Patients 3Pfizer Stops Clinical Trials of Thelin® and Initiates Voluntary Product Withdrawal in the Interest of Patient Safety 2Pfizer Stops Clinical Trials of Thelin® and Initiates Voluntary Product Withdrawal in the Interest of Patient Safety 3Nano squid skin: DOD awards $6M for metamaterials research 2Nano squid skin: DOD awards $6M for metamaterials research 3
Request Info...
... Enzyme concentration - 5 units/µL ,• High ... yields ,• Leaves an 'A' overhang ... polymerase which exhibits very high activity in ... To ensure the quality of the enzyme, ...
... 5 units/µL ,• High specific activity and ... an 'A' overhang ,• Processes ... high activity in primer extension and other ... of the enzyme, each lot has been ...
... Gold® DNA Polymerase is a chemically modified ... chemical moiety is attached to the enzyme, ... the first ramp of thermal cycling (when ... temperatures), the enzyme is inactive. The result ...
Biology Products: