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RING finger protein 5 may guide treatment for muscle disease in older adults
Date:4/4/2008

will now allow further study of the mechanisms underlying this disabling and all too common muscle disease.

We now have a great mouse model that can be used to screen for drugs that might alleviate symptoms of sIBM, says Dr. Ronai. But questions about what may interact with RNF5 in the cell to cause the symptoms of sIBM, he explains, still need to be addressed. We know the substrates for this ubiquitin ligase in C. elegans, but not yet in human muscle.


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Contact: Andrea Moser
amoser@burnham.org
858-646-3146
Burnham Institute
Source:Eurekalert  

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