Navigation Links
Quick test finds signs of diarrheal disease
Date:2/6/2014

Bioengineers at Rice University and the University of Texas Medical Branch (UTMB) at Galveston have developed a simple, highly sensitive and efficient test for the diarrheal disease cryptosporidiosis that could have great impact on global health.

Results from the diagnostic developed by the lab of Rice bioengineer Rebecca Richards-Kortum are read from a paper strip that resembles a pregnancy test. Lines on the strip tell whether samples taken from the stool of a patient contain genetic DNA from the parasite that causes the disease.

The research is detailed online in a new paper in the American Chemical Society journal Analytical Chemistry.

"Diarrheal illness is a leading cause of global mortality and morbidity," said Richards-Kortum, director of the Rice 360˚: Institute for Global Health Technologies. "Parasites such as cryptosporidium are more common causes of prolonged diarrhea. Current laboratory tests are not sensitive, are time-consuming and require days before results are available. A rapid, affordable, accurate point-of-care test could greatly enhance care for the underserved populations who are most affected by parasites that cause diarrheal illness."

A. Clinton White, director of the Infectious Disease Division at UTMB, asked Richards-Kortum to help develop a diagnostic test for the parasite. "I've been working with cryptosporidium for more than 20 years, so I wanted to combine her expertise in diagnosis with our clinical interest," he said. "Recent studies in Africa and South Asia by people using sophisticated techniques show this organism is a very common, underappreciated cause of diarrheal disease in underresourced countries."

The parasite is common in the United States, he said, but less than 5 percent of an estimated 750,000 cases are diagnosed every year. In 1993, an outbreak of cryptosporidium in the water supply sickened 400,000 people in Greater Milwaukee, he said.

Lead author
'/>"/>

Contact: David Ruth
david@rice.edu
713-348-6327
Rice University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Bitter tastes quickly turn milk chocolate fans sour
2. High doses of Vitamin D help tuberculosis patients recover more quickly
3. Quick detection of periodontitis pathogens
4. Protein origami: Quick folders are the best
5. Hand-held device cheaply, quickly diagnosis malaria
6. Oysters could rebound more quickly with limited fishing and improved habitat
7. Cool it, quick: Rapid cooling leads to stronger alloys
8. Finnish researchers develop quick test kit for detecting phenolic compounds in drinking water
9. How quickly can a bacterium grow?
10. Bacteria may allow animals to send quick, voluminous messages
11. Deep Carbon Observatory scientists discover quick recipe for producing hydrogen
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/22/2014)... (FASEB) has released updated factsheets for fiscal ... Institutes of Health (NIH) benefits each of the 50 ... make these factsheets available to help citizens and policymakers ... FASEB President, Margaret K. Offermann, MD, PhD. NIH is ... investing $29.2 billion in FY 2013 in medical research, ...
(Date:4/22/2014)... Analyzing thousands of breeding bird surveys sent in ... Canada over 35 years, wildlife researchers report that most ... northward or toward higher elevation in response to climate ... means that most previous studies of potential climate change ... or the other have likely underestimated the effects of ...
(Date:4/22/2014)... French . , ... complete genome and subsequent phylogenetic analysis show that the ... is distinct from strains previously identified in the Democratic ... linked the laboratory confirmed cases with the initial deaths ... is a lethal, highly contagious virus for which there ...
Breaking Biology News(10 mins):Wildlife response to climate change is likely underestimated, experts warn 2Inserm and the Institut Pasteur identify a new variant of Ebola virus in Guinea 2
... work. Biology researchers at Lewis & Clark College and ... ancient transfer of a toxin between ancestors of two ... remains as how the toxin passed between the two ... journal Bioinformatics, 22(3): 264-268, in an article titled "Lateral ...
... marijuana or its active cannabinoid ingredient alleviates symptoms ... researchers have found that the brain's natural "endocannabinoids" ... to alleviate neuronal damage. However, scientists have not ... own immune system. , Now, experiments by Oliver ...
... Research Associate at the Stowers Institute for Medical Research, ... investigator with the Howard Hughes Medical Institute, have demonstrated ... is expressed in a cyclic fashion during the formation ... embryo. , The findings, which were published in ...
Cached Biology News:Evolution mystery: Spider venom and bacteria share same toxin 2Brain's own cannabis compound protects against inflammation 2Stowers scientists demonstrate mechanism of vertebral formation 2
(Date:1/15/2014)... FALLS, N.Y., Jan. 15, 2014   Niagara Thermal Products ... selected by Buffalo BioBlower Technologies LLC ("B3") as the ... Phase 2 award from the Army Corps of Engineers.  ... that kills all biological contaminants and destroys VOCs and ...
(Date:1/15/2014)... England and SAN JOSE, California ... international biotechnology company developing antibody-drug conjugates for cancer, today announced ... Board of Directors. Dr Reynolds has over 20 years, development ... Medical Officer at Seattle Genetics. "I am delighted ...
(Date:1/15/2014)... IPSWICH, England , January 15, 2014 ... to win races on the Formula 1 track could help ... between McLaren Applied Technologies (MAT), Stowhealth (a GP surgery based ... funded by healthcare provider Simplyhealth. Telemetry technology, which ...
(Date:1/15/2014)... 2014 The Microcompetition with Foreign DNA theory ... of these latent viruses is the Epstein Barr Virus (EBV), ... arthritis (RA) is a chronic inflammatory disease that destroys the ... that RA patients have high concentrations of EBV DNA in ...
Breaking Biology Technology:Niagara Thermal Products LLC Selected as Critical Supplier for Buffalo BioBlower Air Purification Systems 2Oxford BioTherapeutics Appoints Thomas C Reynolds MD, PhD to its Board of Directors 2Oxford BioTherapeutics Appoints Thomas C Reynolds MD, PhD to its Board of Directors 3Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 2Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 3Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 4Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 3
... , ... , ... series documenting,simple protocols for culturing cells in a BioFlo 110,benchtop ... impellers,and control modules to enable growth of a wide variety,of cultures, including ...
... Olive, Ph.D. , Molecular Biology Department , ... Lincoln, NE 68504 , , ... , Optical imaging is ... of a living animal. While several optical imaging modalities employing,fluorescent proteins or bioluminescent reporter ...
... , ... , , ... HPLC by utilizing the Prominence,hardware series. In this respect, we are ... while providing high,reliability and expandability not available with other fast,LC systems., ...
Cached Biology Technology:Insect Cell Culture Using a BioFlo 110 Benchtop Bioreactor 2Insect Cell Culture Using a BioFlo 110 Benchtop Bioreactor 3Insect Cell Culture Using a BioFlo 110 Benchtop Bioreactor 4Insect Cell Culture Using a BioFlo 110 Benchtop Bioreactor 5Insect Cell Culture Using a BioFlo 110 Benchtop Bioreactor 6Near Infrared Technology and Optical Agents For Molecular Imaging 2Near Infrared Technology and Optical Agents For Molecular Imaging 3Near Infrared Technology and Optical Agents For Molecular Imaging 4Near Infrared Technology and Optical Agents For Molecular Imaging 5Near Infrared Technology and Optical Agents For Molecular Imaging 6Near Infrared Technology and Optical Agents For Molecular Imaging 7Prominence UFLC 2Prominence UFLC 3Prominence UFLC 4Prominence UFLC 5Prominence UFLC 6Prominence UFLC 7Prominence UFLC 8
... White lyophilized solid. PROTECT FROM LIGHT. ... inhibitor of γ-secretase. Equipotently inhibits the release ... = 2.6 μM) and Aβ x-42 ... HEK293 cells stably transfected with the Amyloid ...
...
Corticoliberin...
Microlite 2+ Plate, round bottom; an irradiated, high binding surface with enhanced dynamic range, extra high reflectivity and minimal cross talk for low signal luminescent reactions....
Biology Products: