Navigation Links
Quick detection of periodontitis pathogens
Date:1/3/2013

ith two companies, BECIT GmbH and ERT-Optik, to develop a lab-on-a-chip module called ParoChip. In future this will allow dentists and medical labs to prepare samples quickly and then analyze the bacteria. All the steps in the process the duplication of DNA sequences and their detection take place directly on the platform, which consists of a disk-shaped microfluidic card that is around six centimeters in diameter. "Until now, analysis took around four to six hours. With ParoChip it takes less than 30 minutes. This means it's possible to analyze a large number of samples in a short amount of time," says Dr. Dirk Kuhlmeier, a scientist at the IZI.

The analysis is conducted in a contactless and fully automated manner. Samples are taken using sterile, toothpick-shaped paper points, after which the bacteria are removed from the point and their isolated DNA injected into reaction chambers containing dried reagents. There are eleven such chambers on each card, each featuring the reagent for one of the eleven periodontal pathogens. The total number of bacteria is determined in an additional chamber, via polymerase chain reaction (PCR). This method allows millions of copies of even tiny numbers of pathogen DNA sequences to be made. In order to generate the extremely quick changes in temperature that are required for PCR, the disk-shaped plastic chip is attached to a metal heating block with three temperature zones and mechanically turned so it passes over these zones. This causes a fluorescent signal to be generated that is measured by a connected optical measuring device featuring a fluorescence probe, a photo detector and a laser diode. The key benefit is that the signal makes it possible not only to quantify each type of bacterium and thus determine the severity of the inflammation, but also to establish the total number of all the bacteria combined. This enables doctors to fine-tune an antibiotic treatment accordingly.

"As the connected optical measu
'/>"/>

Contact: Dr. Dirk Kuhlmeier
dirk.kuhlmeier@izi.fraunhofer.de
49-341-355-369-312
Fraunhofer-Gesellschaft
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Bitter tastes quickly turn milk chocolate fans sour
2. High doses of Vitamin D help tuberculosis patients recover more quickly
3. Global Information Inc. Announces Discounted Conference Registration For Bio-IT World Asia and Biodetection Technologies 2012
4. Early detection techniques offer hope for improved outcomes in lung cancer patients
5. Virus barcodes offer rapid detection of mutated strains
6. Earlier detection of bone loss may be in future
7. Diving board sensors key to DNA detection
8. Wayne State researchers working to improve genetic analysis, disorder detection
9. By detecting smallest virus, researchers open possibilities for early disease detection
10. Detection, analysis of cell dust may allow diagnosis, monitoring of brain cancer
11. Is the detection of early markers of Epstein Barr virus of diagnostic value?
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Quick detection of periodontitis pathogens
(Date:4/13/2015)... April 13, 2015 According ... "Global Biometrics Market Forecast & Opportunities, 2020", the global ... of around 14% till 2020. The biometrics market ... scale implementation and review of biometric management systems. ... new products with greater efficiency, are resulting in ...
(Date:4/9/2015)... SAN JOSE, Calif. , April 9, 2015 /PRNewswire/ ... of human interface solutions, announced today that it will ... 2015 on Thursday, April 23, 2015, after the close ... call for analysts and investors at 2:00 p.m. PT ... information.    To participate on the live ...
(Date:4/2/2015)... 2, 2015 In the ... far outperforms the strongest competitors, showing outstanding performance ... the system is capable of a throughput of ... up to be ten times faster than most ... performance.      (Photo: http://photos.prnewswire.com/prnh/20150402/738673-a ...
Breaking Biology News(10 mins):Global Biometrics Market to Cross US$ 21 Billion by 2020: TechSci Research 2Synaptics to Report Third Quarter Results on April 23 2DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 2DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 3
... June 15 Robert H. Wurtz, PhD, a pioneer and ... the 2010 Neuroscience Prize of The Peter and Patricia Gruber ... and controls eye movements laid the groundwork for subsequent research ... scientists to a deeper understanding of how the brain is ...
... new study shows that humans and tiny aquatic animals known ... to sex. Barely visible without a microscope, rotifers eat ... But the females of certain rotifer species can do something ... themselves, or they can initiate a process that allows sexual ...
... part of the 20th century have prevented massive amounts ... equivalent of 590 billion metric tons of carbon dioxide ... Stanford Earth scientists. The yield improvements reduced the ... typically involves burning of trees and other plants, which ...
Cached Biology News:Neuroscientist Robert H. Wurtz receives the $500,000 Gruber neuroscience prize 2Neuroscientist Robert H. Wurtz receives the $500,000 Gruber neuroscience prize 3New study documents use of hormone progesterone in simple microscopic aquatic animals 2New study documents use of hormone progesterone in simple microscopic aquatic animals 3New study documents use of hormone progesterone in simple microscopic aquatic animals 4High-yield agriculture slows pace of global warming, say Stanford researchers 2High-yield agriculture slows pace of global warming, say Stanford researchers 3High-yield agriculture slows pace of global warming, say Stanford researchers 4
(Date:5/1/2015)... DALLAS , May 1, 2015 ... report "Antibody Production Market by Product (Equipment, Consumables), by ... (Biopharmaceutical Companies, Diagnostic Labs, Research Institutes) - Analysis ... the report studies the global Antibody Production Market ... This market is expected to reach $2.572 Billion ...
(Date:4/30/2015)... April 30, 2015   Tamir Biotechnology , a ... update on its Ebola antiviral therapy program. ... TMR004, is currently being evaluated and considered by a ... against Ebola. During the first quarter of 2015, the ... To Accelerate The Evaluation of Potential Treatments and Vaccines ...
(Date:4/30/2015)... 2015 Oxford Finance LLC ("Oxford"), a specialty ... and healthcare services companies, today announced the closing of ... Celula, Inc., a diagnostic testing company focused on improving ... care and improved outcomes.  Proceeds of the loan will ... commercialization of its products in the U.S. and ...
(Date:4/30/2015)... , April 30, 2015  Pfenex Inc. ... in the development of biosimilar therapeutics including high ... the closing of its previously announced underwritten public ... at a public offering price of $15.50 per ... the underwriters of their option to purchase up ...
Breaking Biology Technology:Antibody Production Market worth $2.572 Billion by 2019 2Antibody Production Market worth $2.572 Billion by 2019 3Antibody Production Market worth $2.572 Billion by 2019 4Tamir Biotechnology Provides Update on TMR004 Development Against Mutating Ebola 2Tamir Biotechnology Provides Update on TMR004 Development Against Mutating Ebola 3Tamir Biotechnology Provides Update on TMR004 Development Against Mutating Ebola 4Oxford Finance Provides $10 Million Debt Financing to Celula 2Pfenex Inc. Announces Closing of Public Offering of Common Stock and Full Exercise of Underwriters' Option to Purchase Additional Shares 2
... spent time with a leading producer of fashion goods interviewing ... find out what aspects of the shopping experience really matter ... a difference to how much the customer buys and how ... ,Customers were invited to the companys facilities for one-on-one discussions ...
... Promega Corporation and Chemicon ... in which Chemicon may use and apply Madison-based ... ,Under the agreement, Chemicon, California-based division of Serologicals ... technology to develop and sell ddRNAi-based products and ...
... on the effects of outsourcing technology and offshore manufacturing ... Whatever the product, there is an effort to ship ... this are hurting many aspects of Americans industrial and ... whether you manufacture low- to high-tech products, maintain technology ...
Cached Biology Technology:Really Listening to Customers...AND Employees 2Really Listening to Customers...AND Employees 3Offshore outsourcing affects American workers 2Offshore outsourcing affects American workers 3
... marking pen has been designed to provide a thin ... specimen on a slide. This barrier creates the ... the target area on the slide. PAP Pen ... and acetone. It can be removed, if desired, ...
Mouse monoclonal antibody to QDPR - quinoid dihydropteridine reductase...
...
Anti-Conjugated Quinaldic Acid...
Biology Products: