Navigation Links
Queen's scientists seek vaccine for Pseudomonas infection
Date:3/7/2012

Queen's University scientists working on a vaccine to combat Pseudomonas have received a major financial boost from Northern Ireland Chest Heart and Stroke (NICH&S).

The local charity has awarded Queen's Centre for Infection and Immunity a grant of 91,000 to help with their hunt for a vaccine.

Pseudomonas, which can be a killer in vulnerable adults and children, commonly infects the lungs of people suffering from cystic fibrosis (CF). CF damages a number of vital organs, particularly the lungs. It currently affects one in 2,500 newborn babies and Pseudomonas infection occurs in 80 per cent of adults living with CF. Currently in Northern Ireland CF affects 440 people in Northern Ireland, 190 of them children.

If a vaccine can be found, survival rates would increase for those affected by the serious genetic condition.

CF is caused by a genetic defect which results in thick, sticky mucous in the lungs, which becomes infected with bugs, in particular Pseudomonas. These bugs are almost impossible to eradicate, even with long-term antibiotics. This results in damage to the lungs, ultimately leading to early death through breathing difficulties.

Professor Stuart Elborn and Dr Rebecca Ingram, from Queen's Centre for Infection and Immunity are leading the study. Dr Ingram said: "Pseudomonas is around us all the time, and is normally cleared easily from our bodies, however, the mucus in the lungs of CF patients creates a perfect environment for the bacteria to live and multiply.

"In our study, patients' blood cells are placed on a special membrane and then mixed with different parts of the bacteria, to see if the body recognises them and so releases 'attack' molecules to deal with the infection. A dye is used to highlight the spots where this process is happening. It is the first time the technique has been used to examine human responses to Pseudomonas. Knowing which parts of the infection can most easily be recognised by the body will be a key piece in the jigsaw leading to the discovery of a vaccine."

The Chief Executive of NI Chest Heart & Stroke, Andrew Dougal, said: "Cystic fibrosis is a devastating illness primarily affecting the lungs. We are delighted to be supporting this high quality local research at Queen's, which brings hope of a Pseudomonas vaccine to improve survival rates. Often, these research grant awards are made possible only by the generosity of people who bequeath money to us in their wills. Legacies have become a vitally important source of income at a time of economic downturn".


'/>"/>

Contact: Lisa McElroy
lisa.mcelroy@qub.ac.uk
44-289-097-5384
Queen's University Belfast
Source:Eurekalert

Related biology news :

1. Protein love triangle key to crowning bees queens?
2. Clemson University and the University of Queensland form biofuels research partnership
3. Stanford scientists develop gene therapy approach to grow blood vessels in ischemic limbs
4. A*STAR scientists make groundbreaking discovery on stem cell regulation
5. Scripps Florida scientists awarded $3 million to develop new, more effective pain treatments
6. Scientists learn how insects remodel their bodies between life stages
7. UF scientists name new ancient camels from Panama Canal excavation
8. MU scientists study how to improve pesticide efficiency
9. Southern insect scientists to meet in Little Rock
10. Emerge attracts futurists to collaborate with scientists, designers artists is redesign of future
11. Geological Society of America member scientists, students, and colleagues meet in Texas
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/30/2016)... 2016  higi SH llc (higi) announced today ... national brands, industry thought-leaders and celebrity influencers looking ... for taking steps to live healthier, more active ... higi has built the largest self-screening health station ... people who have conducted over 185 million biometric ...
(Date:11/24/2016)... , Nov. 23, 2016 Cercacor today introduced ... and their trainers non-invasively measure hemoglobin, Oxygen ... Rate, and Respiration Rate in approximately 30 seconds. Smaller ... easy and immediate access to key data about their ... a training regimen. Hemoglobin carries oxygen ...
(Date:11/17/2016)... Global Market Watch: Primarily supported by ownership types; ... Academics) market is to witness a value of US$37.1 billion ... Compounded Annual Growth Rate (CAGR) of 10.75% is foreseen from ... 2014-2020. North America is not way ... Europe at 9.56% respectively. Report Focus: ...
Breaking Biology News(10 mins):
(Date:12/9/2016)... 2016 China Cord Blood Corporation (NYSE: ... leading provider of cord blood collection, laboratory testing, hematopoietic ... the results of its 2016 Annual General Meeting, which was ... China . At the Annual ... of KPMG Huazhen LLP as the independent auditors of the ...
(Date:12/8/2016)... ... December 08, 2016 , ... Lajollacooks4u, San Diego’s premier team building ... team building events, new program offerings and company expansion. , This is ... to include groups of over 30 people. Ever since, Lajollacooks4u has seen significant demand ...
(Date:12/8/2016)... , Dec. 8, 2016  Renova™ Therapeutics, ... congestive heart failure and type 2 diabetes, announced ... a novel adeno-associated virus (AAV) vector developed in ... M.D., Ph.D., at Stanford University. The company plans ... paracrine gene therapy product pipeline. ...
(Date:12/8/2016)... OXFORD, England , December 8, 2016 ... Company, has expanded its customisable SureSeq™ NGS panel range with ... - allowing fast and cost-effective study of variants in familial ... copy number variation (CNV) detection on a single small panel ... and hotspot content. This includes all exons for LDLR ...
Breaking Biology Technology: