Navigation Links
Queen's scientists seek vaccine for Pseudomonas infection
Date:3/7/2012

Queen's University scientists working on a vaccine to combat Pseudomonas have received a major financial boost from Northern Ireland Chest Heart and Stroke (NICH&S).

The local charity has awarded Queen's Centre for Infection and Immunity a grant of 91,000 to help with their hunt for a vaccine.

Pseudomonas, which can be a killer in vulnerable adults and children, commonly infects the lungs of people suffering from cystic fibrosis (CF). CF damages a number of vital organs, particularly the lungs. It currently affects one in 2,500 newborn babies and Pseudomonas infection occurs in 80 per cent of adults living with CF. Currently in Northern Ireland CF affects 440 people in Northern Ireland, 190 of them children.

If a vaccine can be found, survival rates would increase for those affected by the serious genetic condition.

CF is caused by a genetic defect which results in thick, sticky mucous in the lungs, which becomes infected with bugs, in particular Pseudomonas. These bugs are almost impossible to eradicate, even with long-term antibiotics. This results in damage to the lungs, ultimately leading to early death through breathing difficulties.

Professor Stuart Elborn and Dr Rebecca Ingram, from Queen's Centre for Infection and Immunity are leading the study. Dr Ingram said: "Pseudomonas is around us all the time, and is normally cleared easily from our bodies, however, the mucus in the lungs of CF patients creates a perfect environment for the bacteria to live and multiply.

"In our study, patients' blood cells are placed on a special membrane and then mixed with different parts of the bacteria, to see if the body recognises them and so releases 'attack' molecules to deal with the infection. A dye is used to highlight the spots where this process is happening. It is the first time the technique has been used to examine human responses to Pseudomonas. Knowing which parts of the infection can most easily be recognised by the body will be a key piece in the jigsaw leading to the discovery of a vaccine."

The Chief Executive of NI Chest Heart & Stroke, Andrew Dougal, said: "Cystic fibrosis is a devastating illness primarily affecting the lungs. We are delighted to be supporting this high quality local research at Queen's, which brings hope of a Pseudomonas vaccine to improve survival rates. Often, these research grant awards are made possible only by the generosity of people who bequeath money to us in their wills. Legacies have become a vitally important source of income at a time of economic downturn".


'/>"/>

Contact: Lisa McElroy
lisa.mcelroy@qub.ac.uk
44-289-097-5384
Queen's University Belfast
Source:Eurekalert

Related biology news :

1. Protein love triangle key to crowning bees queens?
2. Clemson University and the University of Queensland form biofuels research partnership
3. Stanford scientists develop gene therapy approach to grow blood vessels in ischemic limbs
4. A*STAR scientists make groundbreaking discovery on stem cell regulation
5. Scripps Florida scientists awarded $3 million to develop new, more effective pain treatments
6. Scientists learn how insects remodel their bodies between life stages
7. UF scientists name new ancient camels from Panama Canal excavation
8. MU scientists study how to improve pesticide efficiency
9. Southern insect scientists to meet in Little Rock
10. Emerge attracts futurists to collaborate with scientists, designers artists is redesign of future
11. Geological Society of America member scientists, students, and colleagues meet in Texas
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/7/2017)... , February 7, 2017 ... Global Solutions Corporation [OTC: IDGS], ("Ipsidy" or the "Company") ... electronic transaction processing services, is pleased to announce the ... Company. Effective January 31, 2017, Philip ... of Directors, CEO and President.  An experienced payment industry ...
(Date:2/2/2017)... NEW YORK , Feb. 2, 2017  EyeLock ... has released a new white paper " What You ... The problem of ensuring user authenticity is a ... protect the authentication of users. However, traditional authentication schemes ... Biometric authentication offers an elegant ...
(Date:1/26/2017)... Jan. 26, 2017  Crossmatch, a leading provider of ... solution aimed at combatting fraud, waste and abuse in ... at the Action on Disaster Relief conference in ... for UN agencies and foreign assistance organizations throughout ... and abuse are a largely unacknowledged problem in the ...
Breaking Biology News(10 mins):
(Date:2/27/2017)... ... February 27, 2017 , ... ... pasteurized cold-pressed fruit and vegetable drink brand is now available on ... USA, LLC to manufacture and distribute the Vegesentials line of juices throughout ...
(Date:2/27/2017)... , Feb. 27, 2017 /PRNewswire/ - InMed Pharmaceuticals, Inc. ... their expiry on Friday, February 24, 2017 a total of ... price of $0.13 per common share. Proceeds from the exercise ... issued from InMed,s Treasury.   ... "We are grateful for this expression of ...
(Date:2/27/2017)... , February 27, 2017 Four ... for evaluation today, and they are: Anthera Pharmaceuticals Inc. ... of California Inc. (NASDAQ: PACB), and Conatus Pharmaceuticals Inc. ... on ETF Trends, market observers are growing more bullish ... could enact reforms to free cash held overseas for ...
(Date:2/27/2017)... , Feb. 27, 2017 Fluxion Biosciences ... Spain has been appointed as a Certified ... The IsoFlux system will be used in Genetracer Biotech,s ... to lung and colon cancer, with plans to move ... laboratory is utilizing Fluxion,s IsoFlux System to isolate, recover, ...
Breaking Biology Technology: