Navigation Links
Quantitative PET imaging finds early determination of effectiveness of cancer treatment
Date:10/23/2007

RESTON, Va.With positron emission tomography (PET) imaging, seeing is believing: Evaluating a patients response to chemotherapy for non-Hodgkin lymphoma (NHL) typically involves visual interpretation of scans of cancer tumors. Researchers have found that measuring a quantitative indexone that reflects the reduction of metabolic activity after chemotherapy first beginsadds accurate information about patients responses to first-line chemotherapy, according to a study in the October issue of the Journal of Nuclear Medicine.

In our study, we demonstrated that a quantitative assessment of therapeutic response for patients with diffuse large B-cell lymphoma (DLBCL) is more accurate than visual analysis alone when using the radiotracer FDG (fluorodeoxyglucose) with PET scans, said Michel Meignan, professor of nuclear medicine at Henri Mondor Hospital in Creteil, France. The ability to predict tumor response early in the course of treatment is very valuable clinically, allowing intensification of treatment in those patients who are unlikely to response to first-line chemotherapy, he added. Similarly, treatment could possibly be shortened in those patients who show a favorable response after one or two cycles of chemotherapy, and quantification also may help identify the diseases transformation from low-grade to aggressive stage, he explained. However, visual interpretation of PET scans will always be the first step of analysis and will prevail in case of difficulties to quantify images, added Meignan.

Diffuse large B-cell lymphoma is a fast-growing, aggressive form of non-Hodgkin lymphoma, a cancer of the bodys lymphatic system. Although there are more than 20 types of NHL, DLBCL is the most common type, making up about 30 percent of all lymphomas. In the United States, about 63,190 people are expected to be diagnosed with non-Hodgkin lymphoma in 2007, according to recent statistics.

Ninety-two patients with DLBCL were studied before and aft
'/>"/>

Contact: Maryann Verrillo
mverrillo@snm.org
703-652-6773
Society of Nuclear Medicine
Source:Eurekalert

0

GOOD

Page: 1 2

Related biology news :

1. Imaging Lymph Nodes with Nanoparticles
2. New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
3. Special Imaging Study Shows Failing Hearts Are Energy Starved
4. Duke engineers develop new 3-D cardiac imaging probe
5. Confocal imaging promises early detection of skin cancer
6. Newer imaging techniques may lead to over-treatment
7. Researchers use 3-D imaging system to unveil swimming behavior of microscopic plankton
8. Microscopic brain imaging in the palm of your hand
9. New imaging technology shown to detect pancreatic inflammation in type 1 diabetes
10. Purdues gold nanorods brighten future for medical imaging
11. PET imaging reveals the immune system at work
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/15/2008)...g-held assumptions, high-salt diets may not increa...rom the Albert Einstein College of Medicine of Yes...er examining dietary intake among a nationally rep...ein researchers actually observed a significantly ...e (CVD) associated with lower sodium diets. They r...
(Date:5/15/2008)...onal Laboratory has signed a memorandum of underst...ry (SRNL) to collaborate on nuclear energy and env... of critical U.S. Energy Department (DOE) needs an...U allows Argonne to remain a leader in nuclear ene.... "Argonne has the nation,s largest concentration ...
(Date:5/15/2008)...na aggregate under floating objects, such as lengt...ne mammals. There is still no full explanation for... have seen purse-seine fishery operators take adva...shermen cast off floating rafts equipped with buoy...deployed in a wide arc on either side of the vesse...
(Date:5/14/2008)...ux, Security, and Low Power ...swire/ -- Silex Technology today announced,the SX-...ed for connecting,devices that require low power c...orks (WLANs). It is ideal for mobile OEM applicati... usage, such as battery-operated,portable devices ...
Breaking Biology News(10 mins):New study casts further doubt on risk of death from higher salt intake 2Argonne-SRNL agreement supports critical DOE, national priorities 2Does fishing on drifting fish aggregation devices endanger the survival of tropical tuna? 2Does fishing on drifting fish aggregation devices endanger the survival of tropical tuna? 3New Silex SX-560 Enables Enterprise 802.11 Wireless Connectivity for Battery Operated Devices 2NIU Seeks OK for New Proton Cancer Treatment and Research Center 3499 1NIU Seeks OK for New Proton Cancer Treatment and Research Center 3499 2NIU Seeks OK for New Proton Cancer Treatment and Research Center 3499 3Rats on islands disrupt ecosystems from land to sea researchers find 2315 1Rats on islands disrupt ecosystems from land to sea researchers find 2315 2Rats on islands disrupt ecosystems from land to sea researchers find 2315 3Pharsight to Present at eClinical Forum 12678 1Pharsight to Present at eClinical Forum 12678 2Phoenix Academys Therapeutic Community Model Is First to be Federally Recognized as Evidence Based 12673 1Phoenix Academys Therapeutic Community Model Is First to be Federally Recognized as Evidence Based 12673 2
...dvance for human health. It is based on the biocid...m, used in refrigeration towers of factory buildin...s for the proliferation of Legionnaires, disease. ...SMET-Tecnalia experts designed a refrigeration tow...atory (P2 level). A wide range of trials were carr...
...d-seek game between pathogens and the hosts they i... to cloak itself with a recently discovered gene s... by immune cells. , The report by Howard Hughes M...published in the June 2, 2005, issue of Nature may...lencing machinery for its own infectious purposes....
... Figures (pdf download) , Max Planck researcher...by Ernst Abbe in 1873 for diffraction limited reso...o-workers have established a new law that promises...Future applications range from the imaging of cell...ures in microchip manufacturing, and substantial i...
...versity of Toronto has charted how and where a pai... - a discovery that has implications for pain-rela...raumatic stress. , U of T physiology professor Mi...g of Seoul National University in South Korea, an...na have identified where emotional fear memory and...
Other Biology News:Virus uses tiny RNA to evade the immune system 2Virus uses tiny RNA to evade the immune system 3New law for resolution allows unprecedented sharpness in fluorescence microscopy 2New law for resolution allows unprecedented sharpness in fluorescence microscopy 3Study charts origins of fear 2
(Date:5/16/2008)...all/ -- Wyeth (NYSE: WYE ),announced today that i...h,Healthcare Conference on Wednesday, May 21, 2008...will be Greg Norden, Senior Vice President and,Chi...n will be webcast live for investors at, http://ww...e conference., Wyeth is one of the world,s larges...
(Date:5/16/2008)...- George Abercrombie, president,and chief executiv...200,Fort Worth business leaders today at a Rotary ...andemic flu presents businesses with challenges,un...preparedness plans., "While businesses are all to...such as floods or tornadoes," according to Abercro...
(Date:5/16/2008)...metrix Institute (, http://www.metametrixinstitute...ory Evaluations for Integrative and Functional Med...S. Lord and J. Alexander Bralley.,This book follow...tory,Evaluations in Molecular Medicine, published ...of Metametrix Inc., a leader in nutritional and,me...
(Date:5/16/2008)...herapeutics Corporation,announced today that it ha...welve-week Phase IIb trial with oral larazotide ac...ion, for the treatment of patients with active,cel...zed, double-blind,placebo-controlled study will e...fety and tolerability of larazotide acetate in 106...
Breaking Biology Technology:CEO Addresses Fort Worth Business Leaders About Developing Pandemic and Business Continuity Plans 2CEO Addresses Fort Worth Business Leaders About Developing Pandemic and Business Continuity Plans 3Introducing Laboratory Evaluations for Integrative and Functional Medicine 2Alba Therapeutics Announces the Enrollment and Randomization of the First Patient in the Phase IIb Clinical Trial for Larazotide Acetate (AT-1001) for the Treatment of Active Celiac Disease 2Alba Therapeutics Announces the Enrollment and Randomization of the First Patient in the Phase IIb Clinical Trial for Larazotide Acetate (AT-1001) for the Treatment of Active Celiac Disease 3
...Wis. - NameProtect , a Madison-based supplier of...nnounced on Wednesday it has entered a partnership...y headquartered in the state of Oregon. , ,The com...ection System with NameProtection , streamlining .... The pairing will team Fraud Detection System,s t...
...ing is a management tool that is taking the busine...g much of the dedicated coverage of outsourcing to...websites. Thus it was very surprising to me to com...ing published by leading consulting firms - Deloi...te the negative aspects of this management practic...
...Wis. - Alfalight, Inc. , a Madison-based manufac...efense, and telecommunications markets, has been a... Super High Efficiency Diode Sources program, spon...gency. , ,The overall goal of the project is to i...o lower the ambient heat emitted from a laser duri...
...Wis. -- Spanning fewer than a thousand atoms, the...come so miniscule they defy most efforts to charac...e demonstrated a way to image th0se vanishingly sm...study published in the Aug. 1 issue of Applied Ph...r of electrical and computer engineering, and Keit...
Other Biology Technology:Is outsourcing reaching its limits or simply pausing for breath? 2Is outsourcing reaching its limits or simply pausing for breath? 3Is outsourcing reaching its limits or simply pausing for breath? 4Alfalight garners $1.4 million defense funding for diode program 2Engineers chart semiconductors on the scale of atoms 2Engineers chart semiconductors on the scale of atoms 3Engineers chart semiconductors on the scale of atoms 4
Request Info
Request Info
...t GLP facility with capabilities from shake flask ...s development from pilot scale to production. Ase...runs in Batch, Fed-Batch, and Continuous Modes. H...roduct recovery methods include Centrifugation, Mi...
ExonBio Service provides one-stop recobinant protein shopping from cloning, expression and purification. Price including gene cloning.
Biology Products: