Navigation Links
Putting the spring back in broken hearts
Date:9/23/2013

and so yields more functional tissue. Earlier this year, they published research on integrating gold particles into cardiac tissue to optimize electrical signaling between cells.

More recently, the researchers identified spiral-shaped collagen fibers in the extracellular matrix of rat hearts. Seeing the potential for an advance, they set out to recreate them for the first time. After fabricating the spring-like fibers using advanced techniques, they subjected them to a variety of tests.

As the researchers predicted, the spring-like fibers showed better mechanical properties than straight fibers, with especially improved elasticity. And compared to tissue engineered with straight fibers, the tissue engineered with spring-like fibers contracted with greater force and less mechanical resistance.

"These properties are very important, because we want to transplant the tissue into the human heart, which expands and contracts constantly," says Fleischer.

Saving lives

Heart disease is responsible for a third of all deaths in the United States, according to a 2013 American Heart Association report. The researchers in Dr. Dvir's lab hope that tissue engineered with spring-like fibers will help fight this epidemic, improving and prolonging the lives of millions of people.

But additional research is needed first. The researchers say the processes for fabricating the fibers and assembling them into a scaffold need to be refined. Most importantly, they say, the ability of the tissue to improve heart function after a heart attack needs to be tested in humans something they plan to do in pre-clinical and then clinical trials.


'/>"/>

Contact: George Hunka
ghunka@aftau.org
212-742-9070
American Friends of Tel Aviv University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Putting flesh on the bones of ancient fish
2. Kirk, Spock together: Putting emotion, logic into computational words
3. GSA Today: Putting time in its place
4. Putting plants online: 4 leading botanical gardens to create first online catalog of all plants
5. Journal of Control, Automation and Electrical Systems now published by Springer
6. Offspring of mothers stressed during pregnancy with a passive stress coping style more prone to obesity
7. A maternal junk food diet alters development of opioid pathway in the offspring
8. High folate gestational and post-weaning diets in Wistar rat offspring
9. Springer announces impact factor increases for journals in 2012
10. Submarine springs reveal how coral reefs respond to ocean acidification
11. Springer launches French- and Italian-language eBook collections
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... U.S. cities that have seen an increase in so-called ... closures, overwhelmed storm drains and compromised infrastructure--are on the ... , This nuisance flooding, caused by rising sea levels, ... and 925 percent since the 1960s. , The report, ... the United States, also finds Annapolis and Baltimore, Maryland, ...
(Date:7/28/2014)... found that 73 percent of adult survivors of childhood ... syndrome and related health problems by failing to follow ... issue of the journal Cancer . , Almost ... cancer in the study had metabolic syndrome, an umbrella ... abdominal obesity, elevated triglyceride and other abnormalities that often ...
(Date:7/28/2014)... and treat HIV infection has been problematic until now ... arouse as they get rid of the invaders. Now, ... and the National Institutes of Health (NIH) have demonstrated ... around the time of infection could have long-term ... appeared in Nature . , Interferons, named ...
Breaking Biology News(10 mins):NOAA: 'Nuisance flooding' an increasing problem as coastal sea levels rise 2NOAA: 'Nuisance flooding' an increasing problem as coastal sea levels rise 3Unhealthy habits more than double risk of metabolic syndrome in childhood cancer survivors 2Unhealthy habits more than double risk of metabolic syndrome in childhood cancer survivors 3Interfering with interferon 2
... during deployments, U.S. Army units can gain tactical ... and post-conflict operations, and boost overall mission success, ... The study finds that commanders have not ... despite the effect environmental conditions can have on ...
... 23, 2008 Researchers at Sentara Cardiovascular Research Institute begin ... effectiveness of stents to open airways of patients with ... The EASE (Exhale Airway Stents for Emphysema) Trial ... to create new pathways to release trapped air from ...
... out of every three Americans is obese. These individuals are ... to other health problems, such as diabetes. ... the muscle. As a result, accumulated fat by-products inside ... of fat by-products, fat must either be oxidized (burned, as ...
Cached Biology News:Army can boost mission success by better managing 2Army can boost mission success by better managing 3Army can boost mission success by better managing 4Sentara begins international trial -- open at only 24 US locations 2For insulin sensitive overweight patients, 1 session of exercise improves metabolic health 2
(Date:7/25/2014)... California (PRWEB) July 25, 2014 Lawrence ... named to Thomson Reuters list of " The World's ... are part of the 3,000 researchers who were identified ... to recognize those who published the highest-impact work (2002-2012 ... research papers on combustion modeling . , "This ...
(Date:7/25/2014)... At the request of the AMA, ... extension for the public comment period (Docket No. FAA-2014-0396) ... Aircraft established by Congress as part of the FAA ... establishes the new deadline for comments as September 23, ... notice published in the Federal Register on July 25, ...
(Date:7/24/2014)... Tenn., July 24, 2014 -- A novel combination of ... Department of Energy,s Oak Ridge National Laboratory an unprecedented ... its unusual physical and electrochemical properties. , The ... oxygen affects the surface of a perovskite manganite, a ... The new avenue to understand surface behavior could benefit ...
(Date:7/24/2014)... 24, 2014  Asterias Biotherapeutics, Inc. (OTCBB: ASTYV), ... of regenerative medicine, announced today that it will ... investors on Tuesday, July 29, 2014, at 4:30 ... include an overview of Asterias, business strategy and ... http://www.ustream.tv/channel/asterias-biotherapeutics at least 15 minutes before ...
Breaking Biology Technology:Scientists Burst onto Influential List for Combustion Research 2Scientists Burst onto Influential List for Combustion Research 3Scientists Burst onto Influential List for Combustion Research 4FAA Grants Comment Extension at the Request of AMA 2ORNL study reveals new characteristics of complex oxide surfaces 2Asterias Biotherapeutics Announces Live Investor Webcast 2Asterias Biotherapeutics Announces Live Investor Webcast 3Asterias Biotherapeutics Announces Live Investor Webcast 4
... - YM BioSciences Inc. (NYSE Alternext US:YMI, ... develops and commercializes differentiated products for patients ... clearance from Canadian regulatory authorities to initiate ... nimotuzumab, its EGFR-targeting antibody, in combination with ...
... Start of Q4 2008 , - Evaluation of strategic alternatives ... RoleSAN DIEGO, Jan. 5 ADVENTRX Pharmaceuticals, Inc. (NYSE Alternext ... reduction-in-force in an effort to extend its remaining cash and ... a reduction implemented in October 2008. In all, the ...
... Jan. 5 LightLab Imaging Inc. today,announced ... past year that are,the culmination of sustained ... These advances significantly increase the Company,s leadership,position ... OCT is a new,high-resolution, high-speed imaging ...
Cached Biology Technology:YM BIOSCIENCES RECEIVES CLEARANCE TO INITIATE RANDOMIZED DOUBLE-BLIND CLINICAL TRIALS OF NIMOTUZUMAB IN LUNG CANCER AND BRAIN METASTASES FROM LUNG CANCER 2YM BIOSCIENCES RECEIVES CLEARANCE TO INITIATE RANDOMIZED DOUBLE-BLIND CLINICAL TRIALS OF NIMOTUZUMAB IN LUNG CANCER AND BRAIN METASTASES FROM LUNG CANCER 3YM BIOSCIENCES RECEIVES CLEARANCE TO INITIATE RANDOMIZED DOUBLE-BLIND CLINICAL TRIALS OF NIMOTUZUMAB IN LUNG CANCER AND BRAIN METASTASES FROM LUNG CANCER 4YM BIOSCIENCES RECEIVES CLEARANCE TO INITIATE RANDOMIZED DOUBLE-BLIND CLINICAL TRIALS OF NIMOTUZUMAB IN LUNG CANCER AND BRAIN METASTASES FROM LUNG CANCER 5YM BIOSCIENCES RECEIVES CLEARANCE TO INITIATE RANDOMIZED DOUBLE-BLIND CLINICAL TRIALS OF NIMOTUZUMAB IN LUNG CANCER AND BRAIN METASTASES FROM LUNG CANCER 6YM BIOSCIENCES RECEIVES CLEARANCE TO INITIATE RANDOMIZED DOUBLE-BLIND CLINICAL TRIALS OF NIMOTUZUMAB IN LUNG CANCER AND BRAIN METASTASES FROM LUNG CANCER 7ADVENTRX Announces Further Cost-Cutting Measures 2ADVENTRX Announces Further Cost-Cutting Measures 3ADVENTRX Announces Further Cost-Cutting Measures 4ADVENTRX Announces Further Cost-Cutting Measures 5LightLab Imaging Leads Global Advancement of Intracoronary Imaging 2LightLab Imaging Leads Global Advancement of Intracoronary Imaging 3
Request Info...
5-bromouridine 5'-triphosphate (BrUTP) *10 mM in TE buffer*...
Estrogen Receptor (ER) Competitor Assay Kits Green for Estrogen Receptors-alpha and -beta (ER-Alpha and ER-Beta) are ideal for screening novel estrogen receptor binding compounds and endocrine disrup...
Prepared in distilled water....
Biology Products: