Navigation Links
Putting stem cell research on the fast track
Date:9/12/2007

e as a tool in the discovery of new drugs that target stem cells, Dordick said. He explained that although this three-dimensional system can be used to discover materials that support stem cell development and growth, not all stem cells are worth saving. New research is showing that some stem cells could be the precursor for cancer and the reason that cancer reappears after having been totally eradicated by chemotherapy,? he said. With this platform we may be able to rapidly screen new drug candidates that target and kill these stem cells. Instead of going for the mature liver cell that spreads cancer, we can catch a liver stem cell before it can kick off cancer development.

The device will enable drug researchers to quickly screen thousands of small molecules (the basic element of many modern drugs) for their impacts on the fate of stem cells.

Dordicks group was able to prepare up to 1,000 drops as small as 20 nanoliters on a chemically modified slide. The drops contained a mixture of mouse embryonic stem cells encased in a specialized gel. The researchers discovered that in this mixture, the cells remained viable and could be used in various forms of cell-based screening.

Helping Understand Gene Function in Stem Cells

A separate team led by Professor of Chemical and Biological Engineering Ravi Kane and Rensselaer doctoral student Randolph Ashton created a platform that will allow researchers to quickly understand how different genes impact stem cell function or development. Their research will be published in upcoming edition of the journal Stem Cells.

There are millions of DNA bases and tens of thousands of genes within the human genome, Kane said. In order to screen how all these different DNA sequences affect stem cell function you need an extremely high throughput method.

In order to become a specialized organ, tissue, or neural cell, a stem cell needs to be pointed in the right direction, and tha
'/>"/>

Contact: Gabrielle DeMarco
demarg@rpi.edu
518-276-6542
Rensselaer Polytechnic Institute
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Putting ecology back into river restoration
2. Lack of basic research putting patients at risk
3. Putting an old drug to a new use
4. Putting feelings into words produces therapeutic effects in the brain
5. Researchers discover way to make cells in the eye sensitive to light
6. Quantum Dots Research Leads to New Knowledge about Protein Binding in Plants
7. Columbia research lifts major hurdle to gene therapy for cancer
8. Researchers find how protein allows insects to detect and respond to pheromones
9. Researchers Uncover Key Step In Manufacture of Memory Protein
10. Research advances quest for HIV-1 vaccine
11. Research on Worms Yields Clues on Aging
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/5/2015)... May 5, 2015, NXT-ID, Inc. (NASDAQ: NXTD ... on the growing mobile commerce market, reminds investors and media ... Officer, is presenting  at CARTES SECURE CONNEXIONS AMERICA 2015, held ... The three-day conference is organized into a ... in is themed Global Fraud: Where is the Trust ...
(Date:4/27/2015)... , April 27, 2015  For more than ... trade show has been the premier worldwide event for ... 2015 is a must-attend event for any local, national, ... into the emerging commercial markets and current applications of ... innovations of this projected $48 billion industry, and how ...
(Date:4/27/2015)... 2015 NXT-ID, Inc. (NASDAQ: NXTD ) ... on the growing mobile commerce market, announces that its ... the first week of May, 2015 and will be ... Gino Pereira , Chief Executive ... company as Wocket® enters the consumer market. We would ...
Breaking Biology News(10 mins):NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 2NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 3UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 2UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 3UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 4UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 5Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 2Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 3
... Tropical forests hold more living biomass than any other terrestrial ... by Lewis et al. shows that not only do trees ... they hold more carbon now than they did 40 years ... global warming. In a companion article, Helene Muller-Landau, staff scientist ...
... announced the establishment of the Centre for Population Health ... its kind in improving the health of Malaysians. ... and disease, conducting research into the complex relationships between ... the national cancer registry and other related research on ...
... Coffee shrubs, both in themselves and because they are most ... a positive impact on plant and animal diversity in those ... agriculture. What constitutes a dilemma for consumers wishing to ... forest, which is also common, the impact on diversity is ...
Cached Biology News:Cleaning the atmosphere of carbon: African forests out of balance 2Queen's University Belfast improves Malaysian public health 2Coffee cultivation good for diversity in agrarian settlements but not in forests 2
(Date:5/5/2015)... May 5, 2015  Orexigen Therapeutics, Inc. (Nasdaq: ... quarter 2015 on Friday, May 8 before the market ... webcast and conference call at 8:30 a.m. Eastern Time ... may be accessed by phone by calling (800) 708-4540 ... webcast can be accessed live on the Investors section ...
(Date:5/5/2015)... WASHINGTON , May 5, 2015  Indianapolis-based ... adoption of its innovative line of products including ... solution for atraumatically accessing deep-seated brain abnormalities and ... have been completed at more than 50 institutions ... The technology has also been included in 12 ...
(Date:5/4/2015)... SOUTH SAN FRANCISCO, Calif. , May 4, ... a clinical-stage biopharmaceutical company focused on the development ... immuno-inflammatory diseases, announced today the completion of its ... May 4). In conjunction with the closing of ... stock from a combination of new investors and ...
(Date:5/4/2015)... Israel , May 4, 2015  Tikcro Technologies ... its annual report on Form 20-F for the fiscal ... and Exchange Commission ("SEC"). The annual report on Form ... development of antibodies in the area of cancer immune ... superior qualities of high specificity and binding in targeting ...
Breaking Biology Technology:NICO Corporation Gains Market Expansion after Multiple Published Clinical Articles Support Access Technology for Deep Brain Lesions 2NICO Corporation Gains Market Expansion after Multiple Published Clinical Articles Support Access Technology for Deep Brain Lesions 3Tobira Therapeutics Completes Financing and Merger with Regado Biosciences 2Tobira Therapeutics Completes Financing and Merger with Regado Biosciences 3Tobira Therapeutics Completes Financing and Merger with Regado Biosciences 4Tobira Therapeutics Completes Financing and Merger with Regado Biosciences 5Tobira Therapeutics Completes Financing and Merger with Regado Biosciences 6Tikcro Technologies Files Annual Report on Form 20-F for the Year Ended December 31, 2014 2
... ICAAC / IDSA 46th Annual Meeting -, ... Inc. (Nasdaq: MEDX ), a leading monoclonal ... a biodefense company developing medical,countermeasures against biological and ... showing that the anthrax anti-toxin, Valortim(R),(MDX-1303), enhanced survival ...
... health ... market access support, BOSTON, Oct. 28 Boston Healthcare ... President., Mr. Barak brings 16 years of pricing and ... drugs, medical devices, and diagnostics in a wide range of ...
... Tolera,s Monoclonal Antibody Product Candidate -, ... Inc., a,full-service biopharmaceutical development and protein production ... a cGMP contract manufacturing,agreement with Tolera Therapeutics, ... targeted therapies and safer solutions for immune,modulation ...
Cached Biology Technology:Medarex And PharmAthene Announce New Therapeutic Data for Anthrax Anti-Toxin, Valortim(R) 2Medarex And PharmAthene Announce New Therapeutic Data for Anthrax Anti-Toxin, Valortim(R) 3Medarex And PharmAthene Announce New Therapeutic Data for Anthrax Anti-Toxin, Valortim(R) 4Medarex And PharmAthene Announce New Therapeutic Data for Anthrax Anti-Toxin, Valortim(R) 5Medarex And PharmAthene Announce New Therapeutic Data for Anthrax Anti-Toxin, Valortim(R) 6Medarex And PharmAthene Announce New Therapeutic Data for Anthrax Anti-Toxin, Valortim(R) 7Boston Healthcare Appoints Adam Barak as Vice President Enhancing Its International Pricing and Reimbursement Capability 2Laureate Pharma Announces Agreement with Tolera Therapeutics, Inc. 2
...
The Holten mini vertical flow workbench provides a particle-free environment for sample protection against airborne contaminants....
...
... Shakers combine high durability and capacity ... of use. The patented triple-counterbalanced heavy-duty ... to run at high speed with ... temperature range is delivered with tight ...
Biology Products: