Purdue research finds similarities in dog, human breast cancer pre-maligna...(n dogs with breast cancer is that the da...)
n dogs with breast cancer is that the data is outdated, Mohammed said. According to a 1969 study of female dogs over 4 years old that were not spayed, one out of four were expected to develop mammary neoplasia, or abnormal cell growth that may progress to cancer. Thirty percent to 50 percent of canine mammary tumors were malignant, and 50 percent to 75 percent of these recurred or metastasized within one to two years.
"Women have become more aware and conscientious of conducting their own breast self-exams, and pet owners also are more aware to check their animals," Mohammed said. "With better diagnostic tools and early detection, we are able to give dogs the same treatment that we give humans."
Mohammed said the dogs provide a more realistic comparison to humans than the mice and rat models, in part because the tumors developed spontaneously, just as in humans. Dogs have been evaluated in a few studies, but rodent research is more common, she said.
"This is a very large, untapped resource for comparative oncology research," Mohammed said. "Unlike laboratory rodents, dogs share a common environment with people and, therefore, may be exposed to some of the same carcinogens. Also, because dogs have a shorter life span than people, it is possible to study mammary lesions and invasive tumors that develop after a few years instead of decades."
Miller, a veterinary pathologist in the Animal Disease Diagnostic Laboratory, said that mammary cancer in dogs is one of the most common forms of cancer studied at the Animal Disease Diagnostic Laboratory.
"We already had hundreds of mammary tumor specimens archived in the diagnostic laboratory," Miller said. "It's a wonderful thing when we're able to collaborate with other departments at Purdue and Indiana University with these specimens. There's so much to be learned from these types of studies."
Tissue samples are kept indefinitely at the Animal Disease Diagnostic Laboratory,
'/>"/>
| Contact: Maggie Morris maggiemorris@purdue.edu 765-494-2432 Purdue University Source:Eurekalert |
Related biology news :
1. Purdue researchers click nutrition with camera diet study
2. Research shows skeleton to be endocrine organ
3. Newly created cancer stem cells could aid breast cancer research
4. Dominant cholesterol-metabolism ideas challenged by new research
5. Researchers identify proteins involved in new neurodegenerative syndrome
6. Texas researchers and educators head for Antarctica
7. MGH researchers describe new way to identify, evolve novel enzymes
8. University of Pennsylvania researchers develop formula to gauge risk of disease clusters
9. University of Oregon researcher finds that on waters surface, nitric acid is not so tough
10. U of MN researchers discover noninvasive diagnostic tool for brain diseases
11. U of Minnesota researchers discover noninvasive diagnostic tool for brain diseases
 Purdue research finds similarities in dog, human breast cancer pre-malignant lesions |
| Copyright © 2003-2009 Bio-Medicine. All rights reserved. ABOUT | CONTACT US | DISCLAIMER | PRIVACY POLICY | TERMS AND CONDITIONS |  |