Navigation Links
Purdue-designed tool helps guide brain cancer surgery
Date:7/3/2014

WEST LAFAYETTE, Ind. A tool to help brain surgeons test and more precisely remove cancerous tissue was successfully used during surgery, according to a Purdue University and Brigham and Women's Hospital study.

The Purdue-designed tool sprays a microscopic stream of charged solvent onto the tissue surface to gather information about its molecular makeup and produces a color-coded image that reveals the location, nature and concentration of tumor cells.

"In a matter of seconds this technique offers molecular information that can detect residual tumor that otherwise may have been left behind in the patient," said R. Graham Cooks, the Purdue professor who co-led the research team. "The instrumentation is relatively small and inexpensive and could easily be installed in operating rooms to aid neurosurgeons. This study shows the tremendous potential it has to enhance patient care."

Current surgical methods rely on the surgeon's trained eye with the help of an operating microscope and imaging from scans performed before surgery, Cooks said.

"Brain tumor tissue looks very similar to healthy brain tissue, and it is very difficult to determine where the tumor ends and the normal tissue begins," he said. "In the brain, millimeters of tissue can mean the difference between normal and impaired function. Molecular information beyond what a surgeon can see can help them precisely and comprehensively remove the cancer."

The mass spectrometry-based tool had previously been shown to accurately identify the cancer type, grade and tumor margins of specimens removed during surgery based on an evaluation of the distribution and amounts of fatty substances called lipids within the tissue. This study took the analysis a step further by additionally evaluating a molecule associated with cell growth and differentiation that is considered a biomarker for certain types of brain cancer, he said.

"We were able to identify a single meta
'/>"/>

Contact: Elizabeth K. Gardner
ekgardner@purdue.edu
765-494-2081
Purdue University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. White bread helps boost some of the guts good microbes
2. CU researchers explain mechanism that helps viruses spread
3. Tree hugging helps koalas keep their cool
4. Listening helps scientists track bats without exposing the animals to disease
5. Relaxation helps pack DNA into a virus
6. Boosting Immune process with IFN-γ helps clear lethal bacteria in cystic fibrosis
7. The color of blood: Pigment helps stage symbiosis in squid
8. Enzyme helps stem cells improve recovery from limb injuries
9. Extinct relative helps to reclassify the worlds remaining 2 species of monk seal
10. Molecular tumor board helps in advanced cancer cases
11. A transcription factor called SLUG helps determines type of breast cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/11/2015)... Ohio , May 11, 2015  Through a well-rounded ... Ohio had a strong showing at AUVSI,s Unmanned ... These representatives of Ohio,s UAS industry ... and abroad from all points along the UAS ecosystem. ... Development Coalition,s (DDC) Vice President for Aerospace Rich Knoll ...
(Date:5/8/2015)... 2015 Synaptics Inc. (NASDAQ: SYNA ), the ... of the executive management team will present at the following ... and Telecom Conference Date: May 18, 2015 Time: ... MA Cowen and Company Technology, Media ... Location: The New York Palace Hotel, New York, ...
(Date:5/5/2015)... 2015, NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" ... growing mobile commerce market, reminds investors and media that  Mr. ... presenting  at CARTES SECURE CONNEXIONS AMERICA 2015, held in ... The three-day conference is organized into a series of ... themed Global Fraud: Where is the Trust in Cyberspace? ...
Breaking Biology News(10 mins):Ohio Flies High at Unmanned '15, Sets Stage for Ohio UAS Conference 2Synaptics to Present at Upcoming Investor Conferences 2NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 2NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 3
... piece of information to be of any use, one must first ... Nowadays, there is often just too much of it. We are ... night, assisting us to find, digest and comprehend it. In this ... for a barrier-free accessibility of content that can be harvested, extracted, ...
... tiny goggles, scientists say they have learned that the ... stimuli, but also can "learn" time intervals and create ... a team at the Johns Hopkins University School of ... light on learning and memory-making, the investigators say, and ...
... and Ghent, Belgium, January 23, 2013 Hundreds of ... scheduled to convene in Ghent, Belgium, from June 25-28 ... (ICG-Europe 2013). The conference, co-organized by BGI and VIB, ... in plant and animal genomics, metagenomics, as well as ...
Cached Biology News:Pensoft Publishers integrate their journal platform with OpenAIRE 2Pavlov's rats? Rodents trained to link rewards to visual cues 2Pavlov's rats? Rodents trained to link rewards to visual cues 3Pavlov's rats? Rodents trained to link rewards to visual cues 4The 2013 International Conference on Genomics in Europe will take place in Ghent, Belgium 2
(Date:5/21/2015)... (PRWEB) May 21, 2015 Patent Offering, ... method for diagnostic or therapeutic imaging within a body ... uses an endoscope having a low cost, single-use disposable ... filing date was October 18, 2013 and the patent ... technology enables the physician to customize the lighting and ...
(Date:5/21/2015)... Ontario (PRWEB) May 21, 2015 ... into an exclusive North American distribution agreement with ... testing system. , With more than 160 years ... products and services for laboratory and production facilities, ... operational excellence and differentiated services to enable science. ...
(Date:5/20/2015)... DUBLIN , May 19, 2015 Research and ... addition of the "Global Cell Therapy Market Outlook ... Utilization of cell therapy in tissue and regenerative medicine ... are no other options which could help in the ... in this segment but they are unable to form ...
(Date:5/20/2015)... , May 20, 2015  Marc Tessier-Lavigne, president ... gift of $100 million from The Marie-Josée and ... new laboratory building that will be the centerpiece ... Marie-Josée and Henry R. Kravis Research Building, two ... Drive, spanning approximately three city blocks following the ...
Breaking Biology Technology:IpAuctions™ Presents The Worlds Smallest Disposable Illuminated Endoscope For Auction 2IpAuctions™ Presents The Worlds Smallest Disposable Illuminated Endoscope For Auction 3Veolia’s TECTA™ B16 Instrument for E. Coli Detection is Offered Exclusively Through VWR 2Global Cell Therapy Market Outlook 2015-2020 - 262 Cell Therapies & 13 Marketed Cell Therapies 2Global Cell Therapy Market Outlook 2015-2020 - 262 Cell Therapies & 13 Marketed Cell Therapies 3The Marie-Josee and Henry R. Kravis Foundation Provides Landmark Gift of $100 Million to The Rockefeller University 2The Marie-Josee and Henry R. Kravis Foundation Provides Landmark Gift of $100 Million to The Rockefeller University 3The Marie-Josee and Henry R. Kravis Foundation Provides Landmark Gift of $100 Million to The Rockefeller University 4
... KUNMING, China, Nov. 12 /Xinhua-PRNewswire-FirstCall/ -- China ... ("China Shenghuo" or the,"Company"), which is engaged ... pharmaceutical, nutritional supplement and cosmetic products,in the ... the NYSE Alternext,US LLC (formerly the American ...
... Pa., Nov. 12 GEL Interactive,Technologies, a Cadient ... Director, will be a featured speaker at the ... on Defining Appropriate,and Effective Interactions with Thought Leaders ... Forum provides a platform for attendees to interact,and ...
... Nov. 12 Phosphagenics,Limited ("Phosphagenics") (ASX: POH; OTCQX: ... phase 1 human clinical trial using its ... delivery of a leading non steroidal,anti-inflammatory drug ... and penetration of the topically applied Voltaren(R) ...
Cached Biology Technology:NYSE Alternext US Accepts China Shenghuo's Compliance Plan for Continued Listing 2NYSE Alternext US Accepts China Shenghuo's Compliance Plan for Continued Listing 3NYSE Alternext US Accepts China Shenghuo's Compliance Plan for Continued Listing 4Cadient Group's GEL Interactive Technologies to Present and Exhibit at CBI's 5th Annual Forum 2Transdermal Diclofenac enters Phase 1 Clinical Trial in Humans 2
The HQ505, 20 OptiGreen filter for the Molecular Imager FX is a band pass filter used for detection of Cy2 and FITC with 532 nm excitation....
... The APO-BRDU Kit is a 2-color staining ... cellular DNA to detect apoptotic cells by ... and reagents required for measuring apoptosis in ... for assessing reagent performance; washing, reaction and ...
... The ApopTag Red In Situ ... situ by the indirect TUNEL method, ... rhodamine fluorochrome. The kit provides indirect ... are analyzed using either fluorescence microscopy ...
The sample holders for gels are used to hold gels in place in the multi-sample tray I, which is used with Molecular Imager FX imaging systems....
Biology Products: