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Proteins in sperm unlock understanding of male infertility says new study
Date:10/8/2008

developed that target only these proteins and do not produce side effects in the patient or defects in the resulting offspring.

Chu's paper highlights a selection of recent advances in the study of proteins in sperm cells, citing studies that have identified specific proteins that correlate with infertility.

Chu argues that further large-scale clinical studies are needed to identify patterns in the proteins found in the sperm of infertile patients. This would help scientists to better understand which proteins to focus on, since each sperm cell contains more than 2,000 proteins and each patient's sperm varies slightly in its protein content.

Understanding the function of individual proteins in sperm cells may not only aid scientists' understanding of fertility, but can also explain the causes of miscarriages, 50 percent of which have unexplained causes. Chu also suggests that further studies of the proteins found in sperm cells will have a significant impact on our understanding of the paternal protein contribution that can have long lasting effects on future generations.


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Contact: Diana Chu
chud@sfsu.edu
415-405-3487
San Francisco State University
Source:Eurekalert

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