Navigation Links
Proteins in sperm unlock understanding of male infertility says new study
Date:10/8/2008

Proteins found in sperm are central to understanding male infertility and could be used to determine new diagnostic methods and fertility treatments according to a paper published by the journal Molecular and Cellular Proteomics (MCP). The article demonstrates how proteomics, a relatively new field focusing on the function of proteins in a cell, can be successfully applied to infertility, helping identify which proteins in sperm cells are dysfunctional.

"Up to 50 percent of male-factor infertility cases in the clinic have no known cause, and therefore no direct treatment. In-depth study of the molecular basis of infertility has great potential to inform the development of sensitive diagnostic tools and effective therapies," write co-authors Diana Chu, assistant professor of biology at San Francisco State University and Tammy Wu, post-doctoral fellow at SF State. The study is included in a special Oct. 10 issue of MCP dedicated to the clinical application of proteomics.

"We suggest how the study of proteins is useful in the clinic, to help people move from infertile to fertile and ultimately to help couples have a baby," Chu said. "The ultimate goal is that a doctor could be able to say to a patient, 'this is the protein that is misregulated in your sperm and this is the drug that corrects it or decreases the level of that protein.' Understanding sperm proteins also means that a doctor could be able to inform patients of the likely success rates of different fertility therapies, an important factor given the high cost of fertility treatments."

More than 2 million couples in the U.S. are facing infertility. While many scientific studies examine the supply of sperm, its mobility and its ability to fertilize, Chu argues that a wider array of sensitive tests including studies of cell proteins are needed to determine the root causes of male infertility.

Proteins found in sperm cells are unique. This means therapies can be
'/>"/>

Contact: Diana Chu
chud@sfsu.edu
415-405-3487
San Francisco State University
Source:Eurekalert

Page: 1 2

Related biology news :

1. New lab manual focuses on essential methods for purifying and characterizing proteins
2. Saliva proteins could help detection of oral cancer
3. St. Jude study gives new insights into how cells accessorize their proteins
4. NIH awards Argonne $800,000 to develop tool to measure distances within proteins
5. Iowa State University researcher shows proteins have controlled motions
6. Candy-coating keeps proteins sweet
7. Improved technique determines structure in membrane proteins
8. Water is designer fluid that helps proteins change shape, scientists say
9. Novel structure proteins could play a role in apoptosis
10. Scientists reveal the key mechanisms for affinity between transient binding proteins
11. Plant biologists discover unexpected proteins affecting small RNAs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/26/2015)... 26, 2015 The Granite Club, ... and athletic club, today announced it has implemented a ... of movement for members and staff, while restricting access ... process, we selected FST,s IMID Access system because it ... our members and staff, in addition to unparalleled security," ...
(Date:3/24/2015)... Fla. , March 24, 2015   ... management solutions, today announced that its U.are.U ® ... accessory retailer Goorin Bros . to achieve ... biometrics-based solution secures access to the POS terminal, ... increased risk of data breaches. ...
(Date:3/23/2015)... OXFORD, Conn. , Mar. 23, 2015 NXT-ID, Inc. ... authentication company focused on the growing mobile commerce market, announces ... a new advertising campaign on CNBC television starting March 30 ... ads will commence airing in New York ... Executive Officer said: "We are excited about our new ad ...
Breaking Biology News(10 mins):Granite Club First Private Club in North America to Implement FST Biometrics Secure Access Solution, as Part of Multi-million Dollar Expansion 2Crossmatch Fingerprint Readers Help Retailer Prevent Data Breaches at Point-of-Sale 2NXT-ID's Wocket Smart Wallet to Launch New CNBC Regional TV Ad Campaign 2NXT-ID's Wocket Smart Wallet to Launch New CNBC Regional TV Ad Campaign 3
... April 12, 2012 - - Finger ... Biometrics Product Portfolio - - Hitachi Europe ... into a strategic partnership making M2SYS Hitachi,s primary Value Added ... scanner. Biometric Finger Vein identity management scanning technology ...
... subtropical Florida coast, manatees would seem to have a peaceful ... sometimes shattering their ribcages or leaving scars from collisions. Joe ... that many factors put manatees at risk and it isn,t ... For more than 14 years, Mote research has focused on ...
... Environmental policy has historically been driven by a demand-side ... fuels through pollution permits, taxation, and multi-national climate change ... Management at Northwestern University suggests that actually buying coal, ... the ground could be a far better way to ...
Cached Biology News:M2SYS Technology Partners with Hitachi to Offer Innovative Biometric Finger Vein Scanner to US Market 2Manatee hearing good enough to sense approaching motorboats 2Manatee hearing good enough to sense approaching motorboats 3Buy coal? New analysis shows purchasing fossil fuel deposits best way to fight climate change 2
(Date:4/30/2015)... DIEGO , April 30, 2015   Tamir ... announced today an update on its Ebola antiviral therapy ... Tamir,s leading candidates, TMR004, is currently being evaluated and ... of the battle against Ebola. During the first quarter ... And Leadership Meeting To Accelerate The Evaluation of Potential ...
(Date:4/30/2015)... MN , April 30, 2015 /PRNewswire/ - BioAmber ... producing sustainable chemicals, today announced that it has commenced an ... BioAmber expects to grant the underwriters a 30-day option ... the shares of common stock offered in the public ... there can be no assurance as to whether or ...
(Date:4/30/2015)... Va. , April 30, 2015 Oxford ... senior debt to life sciences and healthcare services companies, ... secured term loan agreement with Celula, Inc., a diagnostic ... major diseases, enabling better patient care and improved outcomes. ... the development and expand the commercialization of its products ...
(Date:4/30/2015)... 30, 2015 Biodata, producer of ... integrated protocols and specimen management systems, and ChemAxon, ... consulting services for life science research, announce their ... newest feature: chemical structure and reaction support. Already ... biologists, bio-chemists, and more, the integration of ChemAxon's ...
Breaking Biology Technology:Tamir Biotechnology Provides Update on TMR004 Development Against Mutating Ebola 2Tamir Biotechnology Provides Update on TMR004 Development Against Mutating Ebola 3Tamir Biotechnology Provides Update on TMR004 Development Against Mutating Ebola 4BioAmber Inc. Announces Public Offering Of Common Stock 2BioAmber Inc. Announces Public Offering Of Common Stock 3Oxford Finance Provides $10 Million Debt Financing to Celula 2Labguru Integrates ChemAxon's Marvin JS, to Enhance Functionality for Chemists 2
... VRUS ) management will present at the Third Annual ... 2008 at the Le,Parker Meridien in New York City. ... of the company on Monday,October 6, 2008, from 10:00-10:30 ... Mr. Price,s overview via the internet, log,on to the ...
... DUBLIN, Ireland, October 1 Shire Limited,(LSE: SHP, NASDAQ: ... approval by shareholders at the Annual General,Meeting on September ... Shire,plc with effect from today., Shire plc,s ticker ... ISIN numbers of the Company,s Ordinary shares and American ...
... confirms implementation of quality systems in product ... ... function assay, COLUMBIA, Md., Oct. 1 Cylex ... The 13485:2003 certification,includes compliance with the Canadian Medical Devices ...
Cached Biology Technology:Pharmasset to Present at the JMP Securities Healthcare Focus Conference on Monday, October 6th 2Cylex(TM) Receives ISO 13485:2003 and 9001:2000 Quality Certifications 2
... Incubator/Shaker HT is designed for ... Incubator/Shaker HT is ideal for ... and primer extension assays. iEMS ... a one-cabinet model, allowing the ...
The iEMS Incubator/Shaker is a high performance microplate incubator and orbital shaker. Its superior temperature control and efficient orbital shaking reduce incubation times. -...
...
... PTOs are internucleotide modifications, where ... is replaced by a sulphur atom. This ... PTOs are available as Full-PTOs ... Oligonucleotides with thio-caps Several ...
Biology Products: