Navigation Links
Proteins in gel
Date:6/24/2009

This release is available in German.

Several thousand test fields are tightly packed together on the tiny surface of a biochip. They permit the rapid analysis of substances, e.g. for diagnosing allergens in the blood. These biochips are already in widespread use for DNA testing. When it comes to proteins, such chips are difficult to produce. This is because the proteins have a defined three-dimensional structure by which they can interact specifically with other molecules and control biological processes. If they bind to a surface, such as on a biochip, the structure can be destroyed and the protein cannot perform its function.

Research scientists at the Fraunhofer Institute for Applied Polymer Research IAP in Potsdam-Golm have solved this problem. "We have developed a gel a network of organic molecules that we can apply to the surface of the biochip," says Dr. Andreas Hollnder, group manager at the IAP. "This gel layer is only about 100 to 500 nano-meters thick and consists mainly of water. We thus make the protein believe that it is in a solution, even though it is chemically connected to the network. It feels as if it is in its natural environment and continues to function even though it is on a biochip." Other research groups are working on similar hydrogels. The key feature of the new production technique is that it can be applied in industry, and the gel layers can be manufactured cheaply on a large scale. Usually there are two ways of producing such networks. In the first, complete polymers are chemically bound to the surface. In the second, the polymer molecules are constructed unit by unit on the surface. "Our technique is a mixture of the two known methods. We use larger molecular building blocks to build up the network on the surface," explains Falko Pippig, who is doing his doctorate on this subject at the IAP.

As the hydrogel
'/>"/>

Contact: Dr. Andreas Hollaender
andreas.hollaender@iap.fraunhofer.de
49-331-568-1404
Fraunhofer-Gesellschaft
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Targeting helpers of heat shock proteins could help treat cancer, cardiovascular disease
2. TRAPping proteins that work together inside living cells
3. Pliable proteins keep photosynthesis on the light path
4. Autopilot guides proteins in brain
5. New method for detection of phosphoproteins reveals regulator of melanoma invasion
6. New high-throughput screening technique makes probing puzzling proteins possible
7. Scripps research scientists watch as individual alpha-synuclein proteins change shape
8. Inactivity of proteins behind longer shelf life when freezing
9. Caltech and UCSD researchers shed light on how proteins find their shapes
10. Inhibiting proteins may prevent cartilage breakdown in arthritis patients
11. Tailor-made recombinant proteins in mammals
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Proteins in gel
(Date:7/11/2014)... Researchers have pioneered a revolutionary new way ... called Virtual Finger, allows scientists to move through ... synapses using the flat surface of their computer ... studies orders of magnitude more efficient, saving time, ... many areas of experimental biology. The software and ...
(Date:7/11/2014)... the hippocampus, the marginal division of the striatum ... is the impact degree of substance P in ... function? Yan Yu and his team, College of ... immunofluorescence staining, that substance P receptor, neurokinin 1 ... marginal division of normal rats. Unilateral or bilateral ...
(Date:7/11/2014)... 2014 Research and Markets has ... Market - Industry Analysis Size Share Growth Trends and ... http://photos.prnewswire.com/prnh/20130307/600769 The ... a need for high level security in both private ... such as username and passwords, tokens etc. are vulnerable ...
Breaking Biology News(10 mins):Virtual finger enables scientists to navigate and analyze complex 3D images 2International Biometrics Technology Market - Industry Analysis Size Share Growth Trends and Forecast to 2019 2
... calories leads to a longer life, scientists have proved. ... time that such a diet also can maintain physical ... to physical disability and loss of independence. The study, ... that the diet reduces the amount of visceral fat, ...
... to their social behavior, people sometimes act like monkeys, ... monkey that shares with humans strong tendencies for nepotism ... an expert on primate behavior and an Associate Professor ... University of Chicago. After humans, rhesus macaques are ...
... at Case Western Reserve Universitys School of Medicine ... remarkable discovery with a natural product derived from ... a broad set of applications in various joint, ... bowel syndrome., The publication revealed that Progrado, an ...
Cached Biology News:Severely restricted diet linked to physical fitness into old age 2Humans and monkeys share Machiavellian intelligence 2Humans and monkeys share Machiavellian intelligence 3Natural product discovery by Cleveland medical researchers blocks tissue destruction 2
(Date:7/11/2014)... SEATTLE , July 11, 2014  Researchers ... navigate three-dimensional images. The new technology, called Virtual ... of small structures like neurons and synapses using ... Finger,s unique technology makes 3D imaging studies orders ... resources at an unprecedented level across many areas ...
(Date:7/10/2014)... Canada (PRWEB) July 10, 2014 ... present in very low abundance and are often ... challenging and time-consuming. , Join presenters Dr. Rowel ... and Dr. John Anders, Head of Quality at ... spectrometer-based approach that can speed detection and quantitation ...
(Date:7/10/2014)... 10, 2014 Terascala, the industry leader ... Alan Swahn, a former vice president of product management ... vice president of marketing. Terascala’s software when combined with ... create the highest performance and most reliable solutions for ... guide Terascala’s channel expansion and broaden its product portfolio. ...
(Date:7/10/2014)... 2014 OMICS Group’s 5th International conference ... August, 2014 at Double Tree by Hilton Beijing, China ... in Analytical & Bioanalytical research methods only to facilitate ... this occasion, Dr. Srinubabu Gedela, MD of OMICS Group ... a remarkable one in bringing a unique and international ...
Breaking Biology Technology:Virtual Finger Enables Scientists To Navigate And Analyze 3D Images Of Complex Biological Structures 2Virtual Finger Enables Scientists To Navigate And Analyze 3D Images Of Complex Biological Structures 3Novel Ms Techniques Speed Detection of Biopharmaceutical Product and Process Impurities, New Webinar Hosted by Xtalks 2Terascala Expands Executive Team 2Terascala Expands Executive Team 3A Critical Review of Analytical Techniques for Improved Living Standards 2A Critical Review of Analytical Techniques for Improved Living Standards 3A Critical Review of Analytical Techniques for Improved Living Standards 4
... 19, 2011 Advances that CSL Behring is ... therapeutic needs of patients with hemophilia A and B will ... medical congress on May 22, 2011. CSL Behring is a ... is a subsidiary of CSL Limited (ASX:CSL). ...
... May 19, 2011 Advantagene, Inc., a Massachusetts-based biopharmaceutical ... the U.S. Food and Drug Administration on a Special ... trial of ProstAtak™, its lead agent for patients with ... accrue 711 patients starting mid-2011 with definitive results expected ...
... 19, 2011 Reportlinker.com announces that a ... its catalogue: Global Biosimilars ... This report analyzes the worldwide ... report provides separate comprehensive analytics for US, ...
Cached Biology Technology:Overview of CSL Behring Innovations in Recombinant Technologies Presented at International Conference 2Overview of CSL Behring Innovations in Recombinant Technologies Presented at International Conference 3Advantagene Announces SPA Agreement With FDA to Launch Phase 3 Trial for Novel Vaccine Aimed at Preventing Prostate Cancer Recurrence 2Global Biosimilars Industry 2Global Biosimilars Industry 3Global Biosimilars Industry 4Global Biosimilars Industry 5Global Biosimilars Industry 6Global Biosimilars Industry 7Global Biosimilars Industry 8Global Biosimilars Industry 9Global Biosimilars Industry 10
... The mini incubation trays ... used to screen antigens that ... membrane. Each tray has eight ... channels that accommodate strips cut ...
... analysis and experiment control software. Records ... on-line and off-line analysis. powerful stimulus ... language allowing the user to customize ... Applications range from basic data logging ...
... • Small design specifically for western ... ,Trays are specifically designed for staining western ... x 25 mm) of the disposable tray ... a significant cost savings to the user. ...
... a direct antibiotic-based selection ... Recombinant selection depends solely ... the need for costly ... and inexpensive process provides ...
Biology Products: