Navigation Links
Proteins discovered in gonorrhea may offer new approach to treatment
Date:3/31/2014

CORVALLIS, Ore. Researchers at Oregon State University have discovered novel proteins in, or on the surface of the bacteria that causes gonorrhea, which offer a promising new avenue of attack against a venereal disease that is showing increased resistance to the antibiotics used to treat it.

Only a single, third-generation cephalosporin antibiotic still shows good efficacy against gonorrhea, creating a race against time to find some alternative way to treat this disease that can have serious health effects. It's the second most commonly reported infectious disease in the United States.

Investigations based on these proteins might lead to new ways to combat the disease, including a vaccine, new types of drugs to block the growth of the bacteria, or even restoring the efficacy of some older antibiotics that have lost their usefulness, said Aleksandra Sikora, an assistant professor in the OSU College of Pharmacy.

"This could be a milestone in finding new ways to treat a global problem," Sikora said. "It appears that one or more of these proteins, either within the bacterial cell envelope or on its surface, are essential to its growth and survival. Now we have a new target to aim at."

World health officials have raised alarms that the growing resistance of gonorrhea to antibiotics could cause it to become untreatable. There are more than 60 million cases of this venereal disease treated around the world every year and 300,000 just in the U.S. in people who experience clear symptoms. But some of the worst damage is done among millions of other cases that are very mild or asymptomatic.

Such symptomless infections, most common in women, can cause pelvic inflammatory disease, ectopic pregnancy and infertility, as well as increase the transmission of the HIV virus. Gonorrhea can also affect joints and heart valves, and cause blindness in infants infected during birth.

The new findings were just published in M
'/>"/>

Contact: Aleksandra Sikora
Aleksandra.sikora@oregonstate.edu
541-737-5811
Oregon State University
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. More effective method of imaging proteins
2. Gold nanoantennas detect proteins
3. Discovery of a new family of key mitochondrial proteins for the function and viability of the brain
4. Discovery of plant proteins may boost agricultural yields and biofuel production
5. UCLA researchers develop way to strengthen proteins with polymers
6. Discovered a new checkpoint of cell cycle control through joint action of 2 proteins
7. A non-invasive intracellular thermometer with fluorescent proteins has been created
8. Speeding up drug discovery with rapid 3-D mapping of proteins
9. Identification of differential proteins in maternal serum with Down syndrome
10. Neiker-Tecnalia identifies antitumour proteins in the latex of the plant Euphorbia trigona
11. The appetite-suppressing effect of proteins explained
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Proteins discovered in gonorrhea may offer new approach to treatment
(Date:10/15/2014)... As our ability to assess the pandemic risk from ... developments, we must not allow ourselves to become complacent ... an international consortium of scientists. , Influenza pandemics arise ... have yet to develop widespread immunity – spreads in ... in the past 100 years, the worst of which ...
(Date:10/15/2014)... rapidly and to an unexpected extent. The outbreak does ... the virus shows a new disease dynamic in regions, ... reason, the German National Academy of Sciences Leopoldina, acatech ... the Union of the German Academies of Sciences and ... today. , In the statement the academies call for ...
(Date:10/15/2014)... awarded the 44th Rosenstiel Award for Distinguished Work in ... exploring the mechanisms of genomic instability and its implications ... the second alumnus to win the Rosenstiel Award; the ... , Alt is the Charles A. Janeway Professor of ... and an investigator at the Howard Hughes Medical Institute ...
Breaking Biology News(10 mins):Scientists 'must not become complacent' when assessing pandemic threat from flu viruses 2Academies call for consequences from the Ebola virus epidemic 2Academies call for consequences from the Ebola virus epidemic 3Academies call for consequences from the Ebola virus epidemic 4Academies call for consequences from the Ebola virus epidemic 5Brandeis awards 44th Rosenstiel Award to pioneering geneticist Fred Alt 2
... winds caused by global warming, seeds and pollen are being ... a couple of degrees may increase the dispersal of plants ... forest clearings after felling or forest fires. University ... the impact of global warming on seed and pollen dispersal. ...
... dog owner has not come home to a broken vase ... the house? By ingeniously setting up conditions where the owner ... an offense, Alexandra Horowitz, Assistant Professor from Barnard College in ... dogs in the recently published "Canine Behaviour and Cognition" Special ...
... discovered a potential new way to treat childhood epilepsy ... Gabriella D,Arcangelo and her colleagues have published their research ... (in press) and the paper has just appeared ... the researchers are investigating the molecular basis of the ...
Cached Biology News:Global warming increasing the dispersal of flora in Northern forests 2What really prompts the dog's 'guilty look' 2Rutgers research tackles childhood epilepsy 2
(Date:10/20/2014)... PLAINSBORO, N.J. (PRWEB) October 20, 2014 ... that the Sidney Kimmel Cancer Center at Thomas ... program. , Through the Strategic Alliance Partnership ... and OncLive will collaborate to raise awareness of ... cancer treatment, and other projects. Clinicians and other ...
(Date:10/19/2014)... October 20, 2014 OCTOBER ... Meeting (ABIM). ABIM will take place ... information about ABIM 2014 is now available ... Delegates representing companies and organizations from all ... obtain information on the latest products and ...
(Date:10/19/2014)... Asia-Pacific Speech Analytics market report defines and segments the ... of revenue. This market is estimated to grow from ... at a Compound Annual Growth Rate (CAGR) of 23.9% ... of the Asia-Pacific Speech Analytics market report to get ... provides a glimpse of the segmentation in the market, ...
(Date:10/19/2014)... According to market research report “Outdoor Wi-Fi Market ... Global Advancements, Forecasts and Analysis (2013 - 2018)", ... with analysis and forecasting of the global revenues. ... and the restrains for this market with the ... Browse 65 market data tables and 69 figures ...
Breaking Biology Technology:Sidney Kimmel Cancer Center at Thomas Jefferson University Partners With OncLive 2Sidney Kimmel Cancer Center at Thomas Jefferson University Partners With OncLive 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 2The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 4Outdoor Wi-Fi Market (by Access Points, WLAN Controllers, Wireless gateways) Expected to Cross $37.2 Billion by 2018 - New Report by MarketsandMarkets 2Outdoor Wi-Fi Market (by Access Points, WLAN Controllers, Wireless gateways) Expected to Cross $37.2 Billion by 2018 - New Report by MarketsandMarkets 3Outdoor Wi-Fi Market (by Access Points, WLAN Controllers, Wireless gateways) Expected to Cross $37.2 Billion by 2018 - New Report by MarketsandMarkets 4
... 26 Amedica Corporation, an,orthopedic implants company focused ... U.S. Food and Drug Administration,has granted 510(k) marketing ... Valeo Pedicle Screw system is a low profile ... aimed at allowing surgeons,greater flexibility in the positioning ...
... WALTHAM, Mass., Nov. 26 Millennium Research ... data from both orthopedic surgeons and rheumatologists, shows ... Q3 2007 compared to Q3,2006. While treatments are ... the products they use in these procedures., ...
... Opportunity Presented, CHARLES TOWN, W.Va., Nov. ... RBRM), a provider of treatment for,diabetic peripheral ... successfully concluded analysis of the recent volatility ... the Board of Directors., (Logo: ...
Cached Biology Technology:Amedica Receives FDA 510(k) Clearance for Valeo(TM) Pedicle Screw System 2Hyaluronic Acid Knee Procedures Grow 38% from Q3 2006 to Q3 2007 2ReBuilder Medical Technologies, Inc.'s Recent Stock Price Volatility Explained 2
... controls for monitoring Aldolase tests. 2 ... with targeted manufacturing values at 4 ... 3 IU/L. 30-day shelf life ... C. Level 1: 3 x 3 ...
Request Info...
One-step, microplate or cuvet, colorimetric, linear detection range 0.2 mg/dL to 20 mg/dL. Procedure: 20 min....
Recombinant Mouse Noggin...
Biology Products: