Navigation Links
Proteins: New class of materials discovered
Date:8/22/2014

This news release is available in German.

Thanks to certain helper substances, in PCFs proteins are fixated in a way so as to align themselves symmetrically, forming highly stable crystals. Next, the HZB and Fudan University researchers are planning on looking into how PCFs may be used as functional materials. Their findings are being published today in the scientific journal Nature Communications (DOI: 10.1038/ncomms5634).

Proteins are sensitive molecules. Everyone knows that at least from having boiled eggs. Under certain circumstances like immersion in boiling water they denature, losing their natural shape, and becoming hard. True, researchers have been able to handle these substances for some time now, even to the point of crystallizing them in their native state. Admittedly, though, this does require considerable effort, but it is the only way how researchers can find out the structure of these substances at high resolution. Moreover, protein crystals are extremely fragile, highly sensitive and hard to handle.

Now, for the first time ever, scientists at China's Fudan University have managed to work around these downsides by linking the protein concanavalin A to helper molecules belonging to the sugar family, and to the dye rhodamin. The concanavalin molecules that have been thus fixated tended to arrange themselves symmetrically within the helper molecule framework, forming crystals, in which the proteins achieve high stability and are intricately interconnected into a protein crystalline framework.

Developing molecular structures like these is pointless unless you know exactly how they form and what their structure looks like at the level of the atoms. During the quest for suitable experimental methods, the Shanghai researchers turned to a Chinese scientist working at the HZB for help. She called her colleagues' attention to the MX beamlines at the HZB's electron storage ring BESSY II.

"Here at the HZB, we were able to offer them our highly specialized crystallography stations the perfect venue for characterizing PCFs at high resolutions," says Dr. Manfred Weiss, one of the leading scientists working at the HZB-MX laboratory. It quickly became clear that the helper molecules even allowed the researchers to decide how powerfully they wanted them to penetrate the protein frameworks. "This gives the PCFs a great deal of flexibility and variability, which we'll always keep in mind when doing research on potential applications," says Manfred Weiss.


'/>"/>

Contact: Dr. Manfred Weiss
manfred.weiss@helmholtz-berlin.de
49-308-062-13149
Helmholtz-Zentrum Berlin fr Materialien und Energie
Source:Eurekalert  

Related biology news :

1. Erratic proteins: New insights into a transport mechanism
2. Classic Lewis Carroll character inspires new ecological model
3. SHAREHOLDER ALERT: Pomerantz Law Firm Announces the Filing of a Class Action against Provectus Biopharmaceuticals, Inc. and Certain Officers - PVCT
4. New class of anti-arthritis drugs effectively treats multiple inflammatory diseases
5. Researchers declassify dinosaurs as being the great-great-grandparents of birds
6. Bioelectronics could lead to a new class of medicine
7. Classical monographs re-published in advanced open access
8. New class of nanoparticle brings cheaper, lighter solar cells outdoors
9. Extinct relative helps to reclassify the worlds remaining 2 species of monk seal
10. A tiny, toothy catfish with bulldog snout defies classification
11. Geniposide protects hippocampal neurons via the non-classical estrogen signaling pathway
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Proteins: New class of materials discovered
(Date:12/16/2016)... -- The global wearable medical device market, in terms of value, ... 5.31 billion in 2016, at a CAGR of 18.0% during the ... ... medical devices, launch of a growing number of smartphone-based healthcare apps ... providers, and increasing focus on physical fitness. Furthermore, ...
(Date:12/15/2016)... 2016  There is much more to innovative access ... engine. Continental will demonstrate the intelligence of today,s solutions ... . Through the combination of the keyless entry and ... elements, the international technology company is opening up new ... "The integration of biometric elements brings our ...
(Date:12/7/2016)... According to a new market research report "Emotion Detection and Recognition ... Service, Application Area, End User, And Region - Global Forecast to 2021", published ... in 2016 to USD 36.07 Billion by 2021, at a Compound Annual Growth ... ... MarketsandMarkets Logo ...
Breaking Biology News(10 mins):
(Date:1/19/2017)... ... January 19, 2017 , ... FireflySci Inc. is a go-getter type of ... growth is accounted to two main factors. The first is the amazing customer ... vendors supplying FireflySci products all around the world. , 2016 was a tremendous sales ...
(Date:1/19/2017)... BD (Becton, Dickinson and Company) (NYSE: BDX ... host a live webcast of its Annual Meeting of Shareholders on ... The webcast can be accessed from the BD corporate website at ... 31, 2017. ... About BD BD is a global medical technology company that ...
(Date:1/18/2017)... HACKENSACK, N.J. , Jan. 18, 2017   ... leading the fight to end Duchenne muscular dystrophy ... awarded to the New Jersey Institute of Technology (NJIT) ... ongoing exploration of robotic technology to assist ... study to incorporate NJIT,s technology – an embedded computer, ...
(Date:1/18/2017)... ... January 18, 2017 , ... MYOLYN, which creates ... has submitted a 510(k) to the FDA, requesting clearance of the MyoCycle Home ... stimulation (FES) technology. , The submission marks a major milestone for the ...
Breaking Biology Technology: