Navigation Links
Proteins, like people, act differently when crowded together
Date:12/2/2010

People in a jetliner act and feel one way when crammed together like sardines in a can. But they have quite a different mindset when the middle seat is empty and they have more personal space. Scientists are pursuing a remarkable parallel that exists among the proteins involved in health and disease inside living cells. The cover story in the current issue of Chemical & Engineering News (C&EN), ACS' weekly newsmagazine, focuses on how the study of proteins crowded together inside cells is opening new doors to the prevention, diagnosis, and treatment of disease.

C&EN Senior Editor Celia Henry Arnaud notes that much of the scientific knowledge about proteins comes from research done in watered-down solutions, as if they had much of an airplane or cell to themselves. But cells are packed with proteins, which fill about 30 percent of a cell's volume. In order to understand proteins' actual role, scientists must study proteins under these jam-packed conditions.

The article describes how scientists are forging ahead with research that mimics the real-world conditions under which proteins function in cells. One discovery, for example, indicates that under crowded conditions, a protein involved in Lyme disease changes shape in a way that reveals a potential new target for diagnosing and treating the disease.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related biology news :

1. Neural tissue contains imbalanced levels of proteins, U-M study finds
2. Linking Proteins, Wires, Dots, and Molecules into Useful Devices
3. MSU leads global effort to study link between people, planet
4. The brains of Neanderthals and modern humans developed differently
5. Same types of cell respond differently to stimulus, Stanford study shows
6. Men and women respond differently to stress
7. Why do women store fat differently from men?
8. Heavy pyridine crystallizes differently
9. Nitrous oxide emissions respond differently to no-till depending on the soil type
10. Hatchery-raised salmon too crowded
11. Medical research and magic come together
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... have made some surprising discoveries about the body,s ... virus (SIV), the team found that specialized cells ... responders to viral invasion and are the source ... interleukin-1 beta (IL-1β). , Though aimed at ... the gut epithelium that provides a barrier to ...
(Date:8/29/2014)... at the Barshop Institute for Longevity and Aging Studies, ... Health Science Center at San Antonio, have found another ... rodent, the naked mole rat. , They reported ... rats protects and alters the activity of the proteasome, ... The factor also protects proteasome function in human, mouse ...
(Date:8/29/2014)... has been known about what genetic changes transform wild ... one of whom is a University of Montana assistant ... controlling the development of the brain and the nervous ... was published Aug. 28 in Science and ... at http://www.sciencemag.org/ ., The domestication of animals and ...
Breaking Biology News(10 mins):The early cost of HIV 2Factor in naked mole rat's cells enhances protein integrity 2New research reveals how wild rabbits were genetically transformed into tame rabbits 2New research reveals how wild rabbits were genetically transformed into tame rabbits 3
... are single-celled organisms and a domain unto themselves, quite ... higher organisms. Many species live under extreme conditions, and ... nor with eukaryotes. Methanogenic archaeans, for example, can produce ... underlying chemical reaction, a reduction, involves the cofactor known ...
... German . A good wine needs to ripen. But ... grapevines have to overcome all kinds of obstacles. Extremely hot or rainy ... pests that can appear on the scene. Bugs such as the vine ... as the "Grapevine fanleaf virus" (GFLV for short) can give the vines ...
... of proteins that are highly effective at killing bacteria and ... antibiotics. Researchers from the Universities of York and Leeds ... Research Council (BBSRC) to find out how a family of ... before destroying them. The team, led by Professor Colin ...
Cached Biology News:Rampant helper syndrome 2Virus-resistant grapevines 2
(Date:8/29/2014)... SAN DIEGO, Aug. 29, 2014  Pfenex Inc. ... in the development of high-value and difficult to ... business update and reported financial results for the ... "With the successful completion of our initial public ... advance our biosimilar product candidates, derived from our ...
(Date:8/29/2014)... one of the most promising technologies for future quantum ... (photons) instead of electrons. First, it is necessary to ... and control their direction. Researchers around the world have ... but now scientists at the Niels Bohr Institute have ... one at a time and in a particular direction. ...
(Date:8/29/2014)... 29, 2014 The global companion ... in 2019. It is expected to grow at ... and was valued at $1.8 billion in 2013, ... Market Research. , For more information regarding analysis ... , The research report, titled “Companion Diagnostics Market ...
(Date:8/29/2014)... According to a new market report published by ... was valued at USD 3,754.6 million in 2012 and is ... a CAGR of 5.9% from 2013 to 2019. , Nearly ... afflicted by bone and joint disorders, and this number is ... and will continue to increase the demand for orthobiologics. Other ...
Breaking Biology Technology:Pfenex Reports Second Quarter 2014 Results and Provides Business Update 2Pfenex Reports Second Quarter 2014 Results and Provides Business Update 3Pfenex Reports Second Quarter 2014 Results and Provides Business Update 4Pfenex Reports Second Quarter 2014 Results and Provides Business Update 5Pfenex Reports Second Quarter 2014 Results and Provides Business Update 6Pfenex Reports Second Quarter 2014 Results and Provides Business Update 7Pfenex Reports Second Quarter 2014 Results and Provides Business Update 8Breakthrough in light sources for new quantum technology 2Companion Diagnostics Market to Hit $5.6 Billion in 2019: Transparency Market Research 2Companion Diagnostics Market to Hit $5.6 Billion in 2019: Transparency Market Research 3Global Orthobiologics Market to Reach $5,519.9 Million by 2019: Transparency Market Research 2Global Orthobiologics Market to Reach $5,519.9 Million by 2019: Transparency Market Research 3
... NeoGenomics, Inc. (OTC Bulletin Board: NGNM) today announced ... Equity Conference at 12:30 PM EDT on ... Hotel in Hollywood, FL.  Robert Gasparini, the Company,s ... NeoGenomics, market positioning, financial performance, and strategic direction and then ...
... /PRNewswire-Asia-FirstCall/ -- China-Biotics, Inc.,("China-Biotics", the "Company") (Nasdaq: CHBT ), the leading ... management will present at the Bank of America Merrill Lynch Health,Corporate Day. The ... Merrill,Lynch Client Service Center in Hong Kong . , ... About China-Biotics , ...
... ... The iuvo™ Chemotaxis Assay ... technology to provide quantitative measurements of neutrophil chemotaxis ( ... remains stable over the time period of the assay. ...
Cached Biology Technology:NeoGenomics to Present at Noble Financial's 6th Annual Equity Conference on Monday, June 7th 2NeoGenomics to Present at Noble Financial's 6th Annual Equity Conference on Monday, June 7th 3China-Biotics to Present at Bank of America Merrill Lynch Healthcare Event on June 22 2BellBrook Labs Launches Groundbreaking New Microplate for High Content Chemotaxis Assays in a Stable Gradient 2BellBrook Labs Launches Groundbreaking New Microplate for High Content Chemotaxis Assays in a Stable Gradient 3BellBrook Labs Launches Groundbreaking New Microplate for High Content Chemotaxis Assays in a Stable Gradient 4
Mouse monoclonal antibody raised against a partial recombinant TTC3. NCBI Entrez Gene ID = TTC3...
Mouse polyclonal antibody raised against a partial recombinant SYT4. NCBI Entrez Gene ID = 6860...
Mouse monoclonal antibody raised against a partial recombinant IL31RA. NCBI Entrez Gene ID = IL31RA...
...
Biology Products: