Date:3/5/2009

a 5-6 hours without supply of oxygen and nutrients. Gntert and his colleagues compensated for the concomitant drastic reduction of the measurement time by computational reconstruction of the complete spectrum. Then, they calculated a detailed three-dimensional structure of the protein within E. coli cells using software that was developed in their research group.

The structure determination of proteins by in-cell NMR spectroscopy opens new avenues to investigate at atomic resolution how proteins participate in biological processes in living systems. In-cell NMR spectroscopy advances our understanding of the molecular basis of life, and can contribute to the development of new, better targeted pharmaceuticals.

'/>"/>

Contact: Peter Guentert guentert@em.uni-frankfurt.de 49-697-982-9621 Goethe University Frankfurt Source:Eurekalert

0 GOOD

Page: 1 2
Related biology news :

1. Protein function and chromatin structure methods featured in Cold Spring Harbor Protocols
2. Inactivity of proteins behind longer shelf life when freezing
3. Caltech and UCSD researchers shed light on how proteins find their shapes
4. Calculating gene and protein connections in a Parkinsons disease model
5. Inhibiting proteins may prevent cartilage breakdown in arthritis patients
6. Researchers isolate protein domain linked to tumor progression
7. Scientists study full protein content of bakers yeast
8. New research shows high-quality protein in eggs contributes to power, strength and energy
9. New target for medicine to combat Alzheimers: VIB scientists confirm proteins key role
10. Tailor-made recombinant proteins in mammals
11. Long-sought protein structure may help reveal how gene switch works