Navigation Links
Protein provides link between calcium signaling in excitable and non-excitable cells
Date:10/1/2010

"So it was surprising that the STIM1 protein known to function mostly in non-excitable cells was having a pretty profound effect on the L-type calcium channels".

"This is particularly true in tissue like smooth muscle where it is sort of like a hybrid between an excitable and a non-excitable cell, because it has the voltage-operated calcium channel and the Orai calcium channel, as well as the very powerful STIM sensing system," he said.

Gill said that the researchers' finding gives a common mechanism for calcium signaling in both excitable and non-excitable cells, a link that was never before known.

"It's a very basic finding, but it's another whole area of control that people didn't know about before," he said. "They knew there were L-type calcium channels in many non-excitable cells, but they didn't seem to have any function. Now it seems very possible that the reason they didn't function is that the STIM1 protein was suppressing their function."


'/>"/>

Contact: Preston M. Moretz
pmoretz@temple.edu
215-204-4380
Temple University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Photonic crystal biosensors detect protein-DNA interactions
2. Penn biophysicists create new model for protein-cholesterol interactions in brain and muscle tissue
3. Dont forget the vitamin A when working with its carrier protein
4. Saliva proteins could help detection of oral cancer
5. The structure of the Mre11 protein bound to DNA
6. New lab manual focuses on essential methods for purifying and characterizing proteins
7. Proteins in sperm unlock understanding of male infertility says new study
8. Response to immune protein determines pathology of multiple sclerosis
9. Columbia to award 2008 Horwitz Prize to Arthur Horwich & Ulrich Hartl for cellular protein folding
10. Human protein atlas will help pinpoint disease
11. How neuronal activity leads to Alzheimers protein cleavage
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... fires are visible in in this image of the ... of these were most likely intentionally set in order ... a forest or stand of trees where the land ... deforestation include conversion of forestland to farms, ranches, or ... dark green of the Amazon Rainforest in the middle ...
(Date:8/20/2014)... Ore. -- When are athletes who have suffered concussions ... Oregon study has found that high school athletes who ... 60 days experience a significant regression in their abilities ... The regression, as seen in changes in their balance ... 19 athletes. Ten of the 12 had returned to ...
(Date:8/20/2014)... who are poor experience higher cortisol levels in pregnancy ... the stress hormone, putting them at greater risk ... new research from the University of Colorado Denver. , ... Journal of Human Biology , is the first to ... the socioeconomic status of their mothers during pregnancy. , ...
Breaking Biology News(10 mins):Recovery reversal seen in Oregon study of returning concussed athletes 2Recovery reversal seen in Oregon study of returning concussed athletes 3CU Denver researcher shows economic disparities impact infant health 2
... LANSING, Mich. Researchers from Michigan State University,s departments ... create a new wearable sensor network to assess a ... developed by engineering professor Subir Biswas, participants will wear ... arm and lower leg that during any physical ...
... Southwest Foundation for Biomedical Research (SFBR) in San Antonio ... bad cholesterol to accumulate in the blood as a ... strain of laboratory opossums developed at SFBR that has ... when fed a standard low-cholesterol diet, but extremely elevated ...
... Animal flocks, be it honeybees, fish, ants or ... unanimous decisions at a moment,s notice, a phenomenon which ... published today, Wednesday 15 September, in New Journal ... and German Physical Society), uses a particle model to ...
Cached Biology News:Wearable sensor technology to measure physical activity 2Scientists find gene for high cholesterol in blood 2Understanding behavioral patterns: Why bird flocks move in unison 2
(Date:8/19/2014)... DUBLIN , Aug. 19, 2014 Research and ... Culture Supplies - Global Strategic Business Report" report to their ... Cell and Tissue Culture Supplies in US$ Thousands by the following ... separate comprehensive analytics for the US, Canada , ... Asia-Pacific , and Latin America . ...
(Date:8/19/2014)... IRVINE, Calif. (PRWEB) August 19, 2014 ... Indiegogo campaign to raise $200,000 to fund a ... diagnostic device. , This development is a ... one-size-fits-all model of care to the implementation of ... patient-centric method of practicing medicine. , Indiegogo contributions ...
(Date:8/19/2014)... Robin Williams’ passing is a sad ... an individual. Symptoms range from slowness of voluntary ... and severe depression. Parkinson’s disease progressively gets worse ... producing neurons of the brain. As these patients ... and progressively gets worse, they look for options. ...
(Date:8/19/2014)... , Aug. 19, 2014 ... the addition of the "Spectroscopy Equipment ... report to their offering. ... for Spectroscopy Equipment and Accessories in US$ ... Spectroscopy (UV-Vis spectrophotometers, Raman Spectrometers, NMR-EPR Spectrometers, ...
Breaking Biology Technology:Global Cell and Tissue Culture Supplies - Strategic Business Report 2014 2Cellgen Diagnostics Launches Indiegogo Crowdfunding Campaign for DNA Medical Testing Device 2Cellgen Diagnostics Launches Indiegogo Crowdfunding Campaign for DNA Medical Testing Device 3As We Mourn Robin Williams’ Passing, His Death Sheds Light on Patients Struggling with Parkinson’s Disease 2As We Mourn Robin Williams’ Passing, His Death Sheds Light on Patients Struggling with Parkinson’s Disease 3Global Spectroscopy Equipment and Accessories - Strategic Business Report 2014 2
... International ExpansionConference Call and Webcast to Be Held Today at 5:00 p.m. ET (22:00 CET)NOVATO, Calif., April 30 , ... Item ... Q1 2008 Comparison, Total BioMarin Revenue ... Total Net Product Revenue $71.9 ...
... Medical, an innovator in 3D ultrasound image-guided adaptive ... Whisenhunt to the position of Vice President of ... Company,s growing global sales team and manage partnerships ... of radiation oncology industry experience to the Company. ...
... 30 Tigris Pharmaceuticals, Inc., a privately held drug ... its novel molecule, AFP-464, during the recent AACR 100th ... a significant advancement in the treatment of Triple Negative ... invasive breast cancer," stated Edmundo Muniz, M.D., Ph.D., President ...
Cached Biology Technology:BioMarin Announces First Quarter 2009 Financial Results 2BioMarin Announces First Quarter 2009 Financial Results 3BioMarin Announces First Quarter 2009 Financial Results 4BioMarin Announces First Quarter 2009 Financial Results 5BioMarin Announces First Quarter 2009 Financial Results 6BioMarin Announces First Quarter 2009 Financial Results 7BioMarin Announces First Quarter 2009 Financial Results 8BioMarin Announces First Quarter 2009 Financial Results 9BioMarin Announces First Quarter 2009 Financial Results 10BioMarin Announces First Quarter 2009 Financial Results 11BioMarin Announces First Quarter 2009 Financial Results 12BioMarin Announces First Quarter 2009 Financial Results 13BioMarin Announces First Quarter 2009 Financial Results 14BioMarin Announces First Quarter 2009 Financial Results 15BioMarin Announces First Quarter 2009 Financial Results 16Resonant Medical Expands Sales Organization with Appointment of Vice President of Global Sales and Marketing 2Tigris Pharmaceuticals Presents Results of Breast Cancer Research at AACR Annual Meeting 2Tigris Pharmaceuticals Presents Results of Breast Cancer Research at AACR Annual Meeting 3Tigris Pharmaceuticals Presents Results of Breast Cancer Research at AACR Annual Meeting 4
... lower consumption of reagents and increased ... Multidrop 384 is an automated dispenser ... dispensing into 384- and 96-well plates.This ... can easily switch from 96- to ...
Wellpro 96 an automated liquid handling system for 96-well plates that quickly and accurately prepares large quantities of serial dilutions. The Wellpro also performs plate to plate transfers using ...
... Rotor for use in the ... and Centra-MP4/MP4R. Perfect for ... and other difficult to separate ... containment. Complete with rotor and ...
... The MBS Satellite Thermal Cycler ... flexible solution for medium to ... MBS combines the latest in ... software and PC control, resulting ...
Biology Products: