Navigation Links
Protein love triangle key to crowning bees queens?
Date:11/9/2011

A honey bee becomes a royal queen or a common worker as a result of the food she receives as a larva. While it has been well established that royal jelly is the diet that makes bees queens, the molecular path from food to queen is still in dispute. However, scientists at Arizona State University, led by Adam Dolezal and Gro Amdam, have helped reconcile some of the conflicts about bee development and the role of insulin pathways and partner proteins. Their article "IIS and TOR nutrient-signaling pathways act via juvenile hormone to influence honey bee cast fate" has been published in the December issue of the Journal of Experimental Biology.

Central to the dispute within the scientific community about "who would be queen" has been a ground-breaking study published in the journal Nature by Japanese scientist Masaki Kamakura in 2011. He found that a single protein in royal jelly, called royalactin, activated queen development in larval bees through interaction with an epidermal growth factor receptor (EGFR). Kamakura's work suggested that insulin signals do not play a role in queen development, despite previous studies suggesting otherwise, including work pioneered with the insulin receptor protein by Amdam's group.

Undeterred by Kamakura's findings, Dolezal, a doctoral student, and Amdam, a Pew Biomedical Scholar and professor in ASU's School of Life Sciences, looked for ways to resolve the disparity between the research studies. Amdam's team's first step involved taking control of the insulin receptor's partner protein, IRS, which the insulin receptor relies upon for signaling. The scientists found that by blocking IRS, they caused a central developmental hormone to crash, which forced larval bees into the worker mold despite their diet of royal jelly. Amdam's team then "rescued" the now worker-destined bees. They found that by giving the bees hormone treatments, the bees could then develop along the queen trajectory.


'/>"/>

Contact: Margaret Coulombe
margaret.coulombe@asu.edu
480-727-8934
Arizona State University
Source:Eurekalert  

Page: 1 2

Related biology news :

1. New study uncovers how brain cells degrade dangerous protein aggregates
2. Molecule serves as a key in some protein interactions
3. Rutgers neuroscientist says protein could prevent secondary damage after stroke
4. The tangled web in Alzheimers protein deposits is more complex than once thought
5. Protein microarrays may reveal new weapons against malaria
6. So many proteins, so much promise
7. Gladstone scientists identify protein form linked to Huntingtons disease
8. Researchers build largest protein interaction map to date
9. Gene regulatory protein is reduced in bipolar disorder
10. Bioengineered protein shows preliminary promise as new therapy for hemophilia
11. X-linked mental retardation protein is found to mediate synaptic plasticity in hippocampus
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Protein love triangle key to crowning bees queens?
(Date:9/16/2014)...  Valencell, Inc., a leader in performance biometric data ... "Showcase Companies" representing North Carolina,s ... Venture Conference on September 16-17 th at the ... Raleigh, North Carolina . Valencell,s President Dr. ... the "Digital Health Spotlight Sector" on how the Company,s ...
(Date:9/16/2014)... 16, 2014  Cross Match Technologies, a leading ... today the launch of its Verifier ® ... of an individual using their secure credentials and ... reads credential documents with embedded biometric data and ... biometric to a live scan of their fingerprint. ...
(Date:9/16/2014)... , Sept. 16, 2014 As open enrollment ... important decisions about their 2015 benefits. According to ... solutions business of Aon plc (NYSE: ... a more proactive role in managing their health care ... ever for individuals to understand how they can make ...
Breaking Biology News(10 mins):Valencell, Inc. Selected as 'Showcase Company' at CED Tech Venture Conference 2014 2Cross Match Launches New Identity Management Handheld Solution 2Aon Hewitt Provides Tips to Help Workers Prepare for the Upcoming Open Enrollment Season 2Aon Hewitt Provides Tips to Help Workers Prepare for the Upcoming Open Enrollment Season 3Aon Hewitt Provides Tips to Help Workers Prepare for the Upcoming Open Enrollment Season 4Aon Hewitt Provides Tips to Help Workers Prepare for the Upcoming Open Enrollment Season 5Aon Hewitt Provides Tips to Help Workers Prepare for the Upcoming Open Enrollment Season 6Aon Hewitt Provides Tips to Help Workers Prepare for the Upcoming Open Enrollment Season 7
... TROY, N.Y., Aug. 8 Milliseconds can mean the,difference ... sports,leading more trainers and athletes to look toward technology ... A fluids mechanics professor at Rensselaer Polytechnic Institute ... help,American swimmers sharpen their strokes, shave seconds from their ...
... than a fly buzzing around the house. South Africans have ... bunch of Roridula gorgonias leaves. Attracted to the ... is soon trapped by the natural flypaper. However, this is ... is home to a population of Pameridea roridulae ...
... between triumph and defeat in the world of Olympic ... technology as a tool to get an edge on ... Polytechnic Institute in Troy, N.Y., is using experimental flow ... shave seconds from their lap times, and race toward ...
Cached Biology News:'Top Secret' Technology To Help U.S. Swimmers Trim Times at Beijing Olympics 2'Top Secret' Technology To Help U.S. Swimmers Trim Times at Beijing Olympics 3How nonstick bugs evade natural fly paper 2'Top secret' technology to help US swimmers trim times at Beijing Olympics 2'Top secret' technology to help US swimmers trim times at Beijing Olympics 3
(Date:9/16/2014)... (PRWEB) September 16, 2014 ... initiatives to position themselves for their 89th ... labeling and encoding, Pharma Packaging Solutions is ... hardware and software and new procedures. Establishing ... Good Manufacturing Practices (cGMP), Pharma Packaging Solutions ...
(Date:9/16/2014)... Convoy Therapeutics, Inc., a specialty ... to treat patients directly at the site of ... Technology Platform announced today that John Muraski, Ph.D., ... the White Hat Life Science Investor Conferenceā„¢ on ... In addition, interested individuals can meet Convoy ...
(Date:9/16/2014)... LOUISVILLE, Ky. , Sept. 16, 2014 /PRNewswire/ ... laboratory technologies and products to hospitals, physician office ... announce that, effective October 1, 2014, it will ... in specified hospital market segments and as a ... in the 48 contiguous United States ...
(Date:9/16/2014)... 2014 /PRNewswire-iReach/ -- Researchers found that ActiveLife Scientific,s ... with bone fragility fracture when today,s standard bone ... are at risk of fracture for reasons that ... test, the DEXA bone density scan.  Study results ... and Mineral Research Annual Conference (ASBMR) in ...
Breaking Biology Technology:Adding Serialization Capabilities and Expanded Capacity, Pharma Packaging Solutions Is Preparing for 89th Year of Business 2Convoy Therapeutics to Present at WhiteHat Investor Conference September 18, 2014 2Convoy Therapeutics to Present at WhiteHat Investor Conference September 18, 2014 3LABSCO Secures Alliance With Siemens Healthcare Diagnostics 2LABSCO Secures Alliance With Siemens Healthcare Diagnostics 3ActiveLife's BMSi Test Provides Hope for 160 Million with Undetectable Risk of Bone Fracture 2ActiveLife's BMSi Test Provides Hope for 160 Million with Undetectable Risk of Bone Fracture 3
... Multiporator / Electroporator 2510 , , , , , , , ... Protocol No. 4308 915.501 04/2002 , , , ... , Microorganism , ... Cell type , Bacteria, gram negative, , ...
... , , , , , Multiporator , , , ... Transfection Protocol , Protocol No. 4308 915.045 11/2001 , ... , , , , , ... positive, , MHC class II DR, DQ negative, , ...
... , , , , Multiporator , , , , , ... Transfection Protocol , Protocol No. 4308 915.029 11/1999 , , ... , , Cell line , ... Transfection with , Plasmid pEGFP-N1 (in bidistilled H 2 O), ...
Cached Biology Technology:Actinomyces viscosus 2721.82 2293 T 2
Recalibration of HL-2000-CAL products...
Mature rat whole blood (Sprague-Dawley, averaging 7-8 weeks of age, either sex) is collected at the time of slaughter and processed within 45 minutes. It is then filtered through gauze, pooled in an ...
Several Pichia pastoris strains are available to allow you to optimize expression and recovery of your protein of interest. Table 1 provides information to help you choose the appropriate strain....
...
Biology Products: