Navigation Links
Protein function and chromatin structure methods featured in Cold Spring Harbor Protocols
Date:3/3/2009

COLD SPRING HARBOR, N.Y. (Tues., March 3, 2009) Two new methods for analyzing the roles played by proteins in cells are featured in the March issue of Cold Spring Harbor Protocols (www.cshprotocols.org/TOCs/toc3_09.dtl). Thomas J. Wandless and colleagues from Stanford University (http://wandless.stanford.edu/) provide detailed instructions for "Regulating Protein Stability in Mammalian Cells Using Small Molecules." This technique provides a rapid, reversible, and tunable method for studying the activity of a protein of interest in cells. The protein is attached to a destabilization domain, and the resulting fusion proteins are unstable and degraded, except in the presence of small ligands. The speed of small-molecule binding makes it an attractive alternative to studying gene function using RNA interference (RNAi). The method is freely accessible on the website for Cold Spring Harbor Protocols (http://www.cshprotocols.org/cgi/content/full/2009/3/pdb.prot5172).

The second featured article for March looks at long-range chromosomal interactions and the proteins that mediate them. Stephen Baylin and colleagues from Johns Hopkins University (http://humangenetics.jhmi.edu/index.php?option=com_content&task=view&id=21&Itemid=35) contribute a method for the "Combined 3C-ChIP-Cloning (6C) Assay: A Tool to Unravel Protein Mediated Genome Architecture." 6C technology combines multiple techniques to identify the proteins that bridge distant genomic regions, while simultaneously identifying physical proximities. The method is also useful for determining if a candidate protein might mediate long-range interactions, both in cis and in trans in the nucl
'/>"/>

Contact: David Crotty
crotty@cshl.edu
516-422-4007
Cold Spring Harbor Laboratory
Source:Eurekalert

Page: 1 2

Related biology news :

1. Inactivity of proteins behind longer shelf life when freezing
2. Caltech and UCSD researchers shed light on how proteins find their shapes
3. Calculating gene and protein connections in a Parkinsons disease model
4. Inhibiting proteins may prevent cartilage breakdown in arthritis patients
5. Researchers isolate protein domain linked to tumor progression
6. Scientists study full protein content of bakers yeast
7. New research shows high-quality protein in eggs contributes to power, strength and energy
8. New target for medicine to combat Alzheimers: VIB scientists confirm proteins key role
9. Tailor-made recombinant proteins in mammals
10. Long-sought protein structure may help reveal how gene switch works
11. Scientists uncover new class of non-protein coding genes in mammals with key functions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/18/2015)... Aug. 17, 2015 Research and Markets ... the "Global Biometric Authentication & Identification Market: ... & Forecast, 2015-2020" report to their offering. ... identification systems market is expected to grow at ... 2020 and generate over $25 billion (approximately) by ...
(Date:8/12/2015)... MINNETONKA, Minn. , Aug. 12, 2015   ... that supports the entire spectrum of clinical research, is ... ™ , the company,s comprehensive SaaS-based eClinical technology platform, ... growth during the first two quarters of 2015.   ... and second largest quarters measured by contract value sold ...
(Date:8/12/2015)... Aug. 12, 2015  New research unveiled at ... Android phones to steal users, fingerprints. Information released ... of fingerprint scanners on mobile devices, making the ... secure biometrics on mobile devices, HYPR Corp. recently ... convenient authentication systems with strong cryptographic security. More ...
Breaking Biology News(10 mins):Global Biometric Authentication & Identification Market 2015: Focus On Modality, Motility & Application - Estimation & Forecasts to 2020 for the $25 Billion Industry 2MedNet Solutions Experiences Explosive Corporate Growth 2HYPR Corp. Addresses Android Vulnerability That Exposes Ecosystem-wide Biometric Security Challenges 2HYPR Corp. Addresses Android Vulnerability That Exposes Ecosystem-wide Biometric Security Challenges 3
... Species Act in 1973, over 1,300 endangered species have been ... forthcoming issue of Ecology Letters, Male & Bean assess 14 ... that the length of time species are protected, and the ... in explaining trends. , Overall, about half of species protected ...
... quest for viral-based therapies for cancer , Researchers at ... their work to develop the next generation of effective ... research with genetically engineered viruses studied in mice, published ... of the National Academy of Sciences (PNAS), bring us ...
... For most of us, the word “citrus?conjures up images ... or blood oranges, if you’re a true connoisseur of ... the genus Citrus includes at least 16 species, with ... pummelos, trifoliate oranges, and kumquats. , Krueger, who is ...
Cached Biology News:Columbia scientists develop cancer terminator viruses 2Columbia scientists develop cancer terminator viruses 3From a Few Wild Ancestors, a Citrus Cornucopia 2From a Few Wild Ancestors, a Citrus Cornucopia 3From a Few Wild Ancestors, a Citrus Cornucopia 4
(Date:8/28/2015)... Texas (PRWEB) , ... August 28, 2015 , ... ... Riordan, PhD and orthopedic surgeon, Wade McKenna, DO, announced today that the use ... Dallas, Texas, resulted in complete healing of an otherwise non-healing surgical knee wound. ...
(Date:8/27/2015)... VA (PRWEB) , ... August 27, 2015 , ... ... contractors solve complex business problems, is pleased to announce their ranking as one of ... annual ranking of the fastest-growing private companies across the nation. , “It is truly ...
(Date:8/27/2015)... , Aug. 27, 2015 The ... a patient,s eyes—and life—were saved by doctors at Vanderbilt ... working with NNFF, NovaBay Pharmaceuticals and Dr. John ... Center at Seton Medical Center in ... treatment used a breakthrough approach, pioneered by Dr. Crew, ...
(Date:8/27/2015)... SAN DIEGO , Aug. 27, 2015 ... second annual meeting of the Japan Society of HTLV-1, ... Science Institute Auditorium. The purpose of the Society is ... well as the development of medical technology and research ... health and welfare. "HUYA is proud to ...
Breaking Biology Technology:Dallas-Fort Worth Stem Cell Researchers Use Amniotic Tissue To Successfully Treat Non-Healing Surgical Wound 2Dallas-Fort Worth Stem Cell Researchers Use Amniotic Tissue To Successfully Treat Non-Healing Surgical Wound 3Dallas-Fort Worth Stem Cell Researchers Use Amniotic Tissue To Successfully Treat Non-Healing Surgical Wound 4Capital Edge Consulting Makes Inc. 5000 List of America’s Fastest-Growing Private Companies 2Capital Edge Consulting Makes Inc. 5000 List of America’s Fastest-Growing Private Companies 3Patient's Life and Eyes Saved from Gruesome Flesh-Eating Infection Consuming Her Face 2Patient's Life and Eyes Saved from Gruesome Flesh-Eating Infection Consuming Her Face 3HUYA Bioscience International Sponsors Japan Society Of HTLV-1 Annual Meeting 2HUYA Bioscience International Sponsors Japan Society Of HTLV-1 Annual Meeting 3HUYA Bioscience International Sponsors Japan Society Of HTLV-1 Annual Meeting 4
... Bionovo, Inc.,(Nasdaq: BNVI ), a pharmaceutical company focused ... in the areas of women,s health and,cancer, announced today ... presenting at the BMO Capital Markets 2008 Focus on ... begin at 2:15 PM,ET on Tuesday, August 5, 2008 ...
... CRY ), a,biomaterials, medical device and tissue processing ... to vice president of U.S. sales,and marketing, and that ... international sales and marketing. Both men will report to,Gerald ... marketing.,Additionally, the company has announced the promotion of Timothy ...
... Pharmaceuticals,announced today that it has appointed Kurt Jarnagin, Ph.D., ... pleased to welcome Kurt to the company," said Jacob ... "Kurt,is a noted expert in the field of small ... our team as we continue to,expand our pipeline fed ...
Cached Biology Technology:Bionovo to Present at BMO Capital Markets 2008 Focus on Healthcare Conference 2CryoLife Announces Management Promotions 2CryoLife Announces Management Promotions 3Anacor Pharmaceuticals Appoints Dr. Kurt Jarnagin Vice President of Biological Research 2
... revolutionizes imaging software for the microscopy ... microscopes, cameras, components and peripherals with ... tools. Its intuitive interface simplifies workflow ... while providing powerful features such as ...
BD BioCoat Vented Caps for 175 cm2 Flasks...
BD BioCoat Laminin 60 mm Culture Dishes, tissue-culture treated polystyrene with a uniform application of mouse laminin....
...
Biology Products: