Navigation Links
Protein extremes gain relevance in massive proteomic studies
Date:6/15/2010

ute of Biotechnology and Biomedicine and the Department of Biochemistry and Molecular Biology).

In other words, it is now possible to use massive proteomic methods to study maturing processes of proteins which often include breaks in their linear sequence both internally and at their N- and C-termini. Therefore, it will be possible to assess the specific role of these regions in the processes mentioned and in other related functions such as generation, activation and deactivation of hormones, growth factors, neuropeptides, enzymes, membrane receptors and many other proteins with important biological roles. The strategy developed can be carried out ex-vivo (in cell extracts) or in-vivo (by transfection and proteomic analysis). In addition, protein extremes are commonly involved in essential functions, such as locating and directing cells-tissues, triggering the start of three-dimensional folding, joining other biomolecules and macrostructures, post-generation chemical modifications of proteins, etc.

This publication completes previous studies (e.g. on N-terminal regions) carried out by the Flemish research group, leader in the field of general proteomics, as well as by researchers at Universitat Autnoma de Barcelona, leaders in the field of enzymes processing and maturing C-terminal proteins (carboxypeptidases), who recently published an article on the processing of C-terminal peptides in the Journal of Biological Chemistry, by S. Tanco, J. Lorenzo and F. X. Aviles, of UAB, and Ll. Fricker et. al. of Albert Einsten College of Medicine of New York.


'/>"/>

Contact: Maria Jesus Delgado
MariaJesus.Delgado@uab.cat
34-935-814-049
Universitat Autonoma de Barcelona
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Protein could heal erectile dysfunction after cancer surgery
2. A balanced protein diet can reduce accumulation of nitrogen on dairy cattle farms by up to 35 percent
3. New function discovered in cancer prevention protein
4. Neural tissue contains imbalanced levels of proteins, U-M study finds
5. MIT chemists design new way to fluorescently label proteins
6. Bodys own proteins may lead the way in global fight against tuberculosis
7. Novel protein essential for successful pregnancy
8. Protein regulates enzyme linked to Alzheimers disease
9. Intracellular express -- why transport protein molecules have brakes
10. Protein power for Jack and the beanstalk
11. Study finds protein that plays key role in early embryonic development
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Protein extremes gain relevance in massive proteomic studies
(Date:12/19/2014)... , Dec. 18, 2014 Research and Markets ... of the "Micro Market Monitor: North America Perimeter ... http://photos.prnewswire.com/prnh/20130307/600769 The ... at a CAGR of 3.6% from 2014 to 2019. ... this market, Canada is expected ...
(Date:12/17/2014)... 15, 2014 Research and Markets ... the "Samsung Galaxy S5 - Home Button ... their offering. http://photos.prnewswire.com/prnh/20130307/600769 ... sensing technology than the iPhone 5S, Samsung introduces ... its product. The Galaxy S5 home ...
(Date:12/17/2014)... , Dec. 16, 2014 Valencell, a ... its PerformTek biometric technology to industry leaders such as ... accurate, clinically validated, biometric wearable products. These products will ... in Las Vegas . ... is accurate, flexible and robust – with the clinical ...
Breaking Biology News(10 mins):Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 3Samsung Galaxy S5 - Home Button Synaptics Fingerprint Sensor Technology Analysis 2Valencell PerformTek Biometrics Power the Most Accurate Wearables at CES 2015 2
... a gene called p63 accelerates aging in mice. Similar versions ... Therefore, the p63 gene is likely to play a fundamental ... p63 gene works, we devised a system for eliminating it ... that these p63 deficient mice were aging prematurely," says Alea ...
... a genetic study has followed a single humpback whale ... notions of the migratory patterns of these majestic marine ... Wildlife Conservation Society (WCS), the American Museum of Natural ... recent Royal Society's Biology Letters, a male humpback whale ...
... of the varicella (chicken pox) vaccine in 1995, hospitalizations ... dramatically, according to a study in the August 17 ... routine immunization of children aged 12 to 18 months ... United States, according to background information in the article. ...
Cached Biology News:Gene loss accelerates aging 2Genetics links whale to two different ocean basins 2Hospitalizations because of chicken pox down dramatically since implementation of vaccine 2Hospitalizations because of chicken pox down dramatically since implementation of vaccine 3
(Date:12/24/2014)... MD (PRWEB) December 23, 2014 ... into law H.R. 83, the Omnibus and Continuing ... first time, made hydrocephalus a condition eligible to ... Programs (CDMRP) administered by the Department of Defense ... with its allies on Capitol Hill, is celebrating ...
(Date:12/24/2014)... December 24, 2014 The report expects ... 19.7% by 2019. It also provides a carefully analyzed ... and challenges for the market. , Full Copy of ... report, the global market for cell expansion will keep ... It expects this growth to be driven by rapid ...
(Date:12/24/2014)... December 23, 2014 PharmaBoardroom,s ... out today and available for free download , digs ... change and growth in the sector today. One ... successes has been in developing a homegrown pharmaceutical manufacturing base, ... production still remains some way off. A cursory comparison with ...
(Date:12/22/2014)... The Center for Professional Innovation ... training across the life sciences industry, has partnered with ... to provide the organization's members with discounted classroom courses, ... the more than 350 sessions across 80 course titles. ... when registering for a public course at ...
Breaking Biology Technology:Rare Brain Condition Now Eligible for Department of Defense Research Dollars 2The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 2The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 3PharmaBoardroom Releases New Algeria Pharmaceuticals Report 2PharmaBoardroom Releases New Algeria Pharmaceuticals Report 3CfPIE Announces Partnership with the Society for Clinical Data Management 2CfPIE Announces Partnership with the Society for Clinical Data Management 3
... Inc. (Nasdaq: HGSI ) today announced that ... financial results for the year ended December 31, 2008. ... Thursday, February 26, 2009, after the capital markets close.(Logo: ... hosted by senior management and will be held on ...
... Feb. 19 Based on its recent analysis of ... Inc. with the 2009 North American Frost & Sullivan ... Award recognizes the company,s impressive progress in developing to ... guidance system that is set to redefine the standard ...
... -- Progen board; - finally ... Meeting; ... buyback; and - persists with ... meeting with refusal to align meeting datesShareholder Meeting scheduled for 27 ...
Cached Biology Technology:Human Genome Sciences to Sponsor Conference Call to Discuss Full Year 2008 Financial Results 2Frost & Sullivan Names Naviscan a Leader in the Future of Molecular Breast Imaging 2Frost & Sullivan Names Naviscan a Leader in the Future of Molecular Breast Imaging 3Frost & Sullivan Names Naviscan a Leader in the Future of Molecular Breast Imaging 4Progen Concedes Shareholder Requisitioned Meeting 2Progen Concedes Shareholder Requisitioned Meeting 3Progen Concedes Shareholder Requisitioned Meeting 4Progen Concedes Shareholder Requisitioned Meeting 5
Mus musculus MARCKS-like protein, mRNA...
... from BRAND adds ergonomics and ease-of-use ... only electronic, motor-driven repeating pipette compatible ... BRAND PD-Tip syringe tips, Eppendorf Combi-Tips ... VWRbrand Combi-Syringes. Select virtually any pipetting ...
... can be used for efficient, mild and ... for ELISA or other assays for protein ... are bound with high efficiency to the ... will not elute during the assay due ...
Activating Agents, 7-azabenzotriazol-1-yloxy-tris-(pyrrolidino)phosphonium hexafluorophosphate...
Biology Products: