Navigation Links
Prosthetic vein valve designed to direct blood flow shows promising pre-clinical results
Date:9/15/2008

and testing it in the laboratory. When the Georgia Tech researchers started designing the valve, they wanted it to be as similar as possible to normal, anatomic venous valves. They focused on two major design criteria: the valve had to withstand high pressures without leaking and the valve had to open with small pressure gradients, even after 500,000 cycles of opening and closing, which is equivalent to a half year.

"It was important for us to test the long-term feasibility of these valves because they're going to be implanted and used for years," explained Ku. "But since test methods have not been well established for evaluating a prosthetic vein valve, we developed our own."

Sathe conducted the initial laboratory tests and found that the valve met the mechanical design criteria it could withstand pressures of more than 500 millimeters of mercury and opened with a pressure gradient of 2.6 millimeters of mercury, which matched physiologic vein valve function. Detailed laboratory testing procedures and results were described in the June 2007 issue of the Journal of Medical Devices.

Next, Farrell developed a laboratory method to test whether blood clots would form inside the prosthetic valve. Results showed that the new generation of valves remained open with no clot formation after 120 minutes of blood flow, whereas control valves lined with polyester closed up after approximately six minutes of perfusion and showed blood cells adhering to the valves.

The laboratory tests showed that the prosthetic vein valve exhibited low flow resistance, strong competency, fatigue-resistance, low clot formation probability and material flexibility, which allowed the researchers to move forward to the animal studies.

The next step after conducting the animal studies will be human clinical trials. The device will require an investigational device exemption from the Food and Drug Administration so that the device can be used in a clinical
'/>"/>

Contact: Abby Vogel
avogel@gatech.edu
404-385-3364
Georgia Institute of Technology Research News
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. MIT aids creation of neural prosthetic devices
2. Thinking makes it so: Science extends reach of prosthetic arms
3. Portable electricity, life-like prosthetics on the way
4. When bivalves ruled the world
5. Endobronchial valve significantly improves emphysema
6. Book is the first high-resolution digital mouse brain atlas designed for Web applications
7. Specially-designed soils could help combat climate change
8. New, more direct pathways from outside the cell-to-cell nuclei discovered
9. 4,000 e-Books now available on ScienceDirect
10. Michael A. Betts, Seasoned Financial Services Executive, Joins CIC Board of Directors
11. Office of the Director of National Intelligence, CIO to Speak at Government Security Conference
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Prosthetic vein valve designed to direct blood flow shows promising pre-clinical results
(Date:1/22/2015)... 2015 Infinisource has launched its new NXG series of ... G2 sets a higher standard for collecting attendance and labor ... With plug-and-play installation, touch screen interface and seamless connection to ... time collection solution for the small to mid-size employer. ...
(Date:12/22/2014)... , Dec. 22, 2014  The 2014 Holiday Season ... as Acuity Market Intelligence reports that the long anticipated ... forecasts that intensifying demand for smart phones, tablets, and ... global market of 2.5 billion users with nearly 4.8 ...
(Date:12/19/2014)...   LaunchKey , the first decentralized mobile authentication and ... Things era, today announced the close of $3 million ... by Metamorphic Ventures with participation from ENIAC Ventures, Crosslink ... LaunchKey has raised $4 million to date, and will ...
Breaking Biology News(10 mins):Infinisource's NXG series sets new time clock standard 2First Season of Holiday Shopping with Mobile Biometric Payments Wraps Up With a Present for Biometrics Industry: A Rosy Forecast for More Than 2 Billion Users of 4.8 Billion Mobile Biometric Devices by 2020 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 3
... led by the Karolinska Institutet, Sweden and the University of ... and the composition of human gastrointestinal bacteria. In a study ... the team outline new evidence suggesting that the human genome ... billions of microbes in the human gastrointestinal tract collectively known ...
... senior author Morris J. Birnbaum, MD, PhD, the Willard ... for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, ... works in a different way than previously understood. Their ... hormone glucagon,s ability to generate an important signaling molecule, ...
... cells in all higher organisms cells need to bind to ... tissues. Mysteries have remained, however, about exactly how cells manage ... Scripps Research Institute (TSRI) have now solved part of this ... α-catenin, which is essential to this process. The ...
Cached Biology News:International study suggests human genes influence gut microbial composition 2Most-used diabetes drug works in different way than previously thought 2New study defines the long-sought structure of a protein necessary for cell-cell interaction 2
(Date:1/23/2015)... Portal Solutions , a technology consulting firm that ... 365 and SharePoint platforms , today announces its inclusion in ... of the region’s fastest-growing mid-sized companies based on a combined ... be recognized a second year in a row by SmartCEO ...
(Date:1/22/2015)... 22, 2015  Transwestern | RBJ today announces the firm brokered ... for Shire a leading biopharmaceutical company, at Two Ledgemont Center ... Robert Richards , president, and Brian Cohen , ... entire five-floor building at 95 Hayden Ave. Photo ...
(Date:1/22/2015)... Pipette.com has added the Eppendorf Centrifuge ... of Eppendorf products. , The Eppendorf Centrifuge 5424/5424 R ... R and receive the following:, ,     Free ... Eppendorf Reference 2 ,     3 Free boxes ...
(Date:1/22/2015)... Diagenode, Inc., a leading global provider ... complete solutions for epigenetics research, recently launched a ... need for manual processing. The new ChIPettor System ... histones or transcription factors and a semi-automated pipette ...
Breaking Biology Technology:Washington SmartCEO Announces Portal Solutions as 2015 Future 50 Award Winner Second Year in a Row 2Washington SmartCEO Announces Portal Solutions as 2015 Future 50 Award Winner Second Year in a Row 3Transwestern?RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Eppendorf Announces Promotional Bundle Which Includes: Eppendorf Centrifuge 5424, 3-Pack of Pipettes, and Tips - Available Now at Pipette.com 2Diagenode Launches Unique Semi-Automated Solution for Chromatin Immunoprecipitation 2
... most popular among makers of ... EVANSTON, Ill., Sept. 30 The ... by global sales and marketing,consulting firm ZS ... number of companies - in pharmaceutical/biotech, medical,products ...
... (Nasdaq: VRNM ), a pioneer in the ... announced today,that Janet Roemer, Executive Vice President and ... upcoming William Blair & Company 2008,Small-Cap Growth Stock ... a.m. ET on Tuesday, October 7, 2008 and ...
... Genomic,Health, Inc. (Nasdaq: GHDX ) today announced ... Officer, will present at the JMP,Securities Healthcare Focus ... at 10:00 a.m. ET., To access the ... the Investor Relations section of Genomic Health,s,website at ...
Cached Biology Technology:Quota-Based Compensation Plans Outpace Ranking Plans 2Quota-Based Compensation Plans Outpace Ranking Plans 3Verenium Corporation to Present at the William Blair & Company 2008 Small-Cap Growth Stock Conference 2Verenium Corporation to Present at the William Blair & Company 2008 Small-Cap Growth Stock Conference 3
Rabbit polyclonal antibody to Neuromedin U Receptor 1 (GPR66)...
... in-house demand is causing shortages in your ... This can cause unwanted distractions, problems and ... royalties for your hard work and endeavour! ... build it up,and market it internationally. We ...
... is causing shortages in your laboratory or ... cause unwanted distractions, problems and delays. ... your hard work and endeavour! Bring us ... up,and market it internationally. We work under ...
...
Biology Products: