Navigation Links
Prosthetic vein valve designed to direct blood flow shows promising pre-clinical results
Date:9/15/2008

et their symptoms rather than the cause. Damaged vein valves can sometimes be repaired, but when that isn't possible, some surgical options are available to replace deep venous valves, such as valve transplantation. However, replacing the valve with a prosthetic one is likely the better option because finding a suitable donor valve in one of the patient's legs can be difficult, according to Ku.

"Previous studies have shown that even if a donor valve is found, implanting it can cause significant trauma to the patient's leg," explained Ku, who has doctoral degrees in mechanical engineering and medicine. "To avoid these complications, other prosthetic vein valves have been designed, but most have demonstrated poor clinical potential for humans."

Ku and his collaborators believe the valve they have developed will overcome previous difficulties. The one-way flap is made of poly(vinyl alcohol) cryogel, a material patented by Georgia Tech in 1999. The material has many useful attributes, including its biocompatibility with body tissue because of its attraction to water; the ability to adjust its mechanical strength; flexibility comparable to that of natural body tissue; and composition of organic polymer, rather than silicone.

The researchers will begin conducting preclinical animal trials at Emory University in October to test the in vivo biocompatibility and performance of the prosthetic vein valve prototype in sheep. Sheep were chosen because their cardiovascular geometry and physiology are similar to those of humans.

In each animal trial, two prosthetic vein valves will be implanted by Milner. The researchers will test the biocompatibility and performance of the devices for four weeks, using imaging techniques to check that the valves remain in the proper location, are open and allow blood to pass through the vein.

The animal trials will be conducted after several years of optimizing the valve design
'/>"/>

Contact: Abby Vogel
avogel@gatech.edu
404-385-3364
Georgia Institute of Technology Research News
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. MIT aids creation of neural prosthetic devices
2. Thinking makes it so: Science extends reach of prosthetic arms
3. Portable electricity, life-like prosthetics on the way
4. When bivalves ruled the world
5. Endobronchial valve significantly improves emphysema
6. Book is the first high-resolution digital mouse brain atlas designed for Web applications
7. Specially-designed soils could help combat climate change
8. New, more direct pathways from outside the cell-to-cell nuclei discovered
9. 4,000 e-Books now available on ScienceDirect
10. Michael A. Betts, Seasoned Financial Services Executive, Joins CIC Board of Directors
11. Office of the Director of National Intelligence, CIO to Speak at Government Security Conference
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Prosthetic vein valve designed to direct blood flow shows promising pre-clinical results
(Date:8/20/2015)... ., Aug. 20, 2015 NXT-ID, Inc. (NASDAQ: ... authentication company focused on the growing mobile commerce market ... has joined The Smart Card Alliance and the EMV ... Alliance and the Smart Card Alliance Latin America (SCALA) ... industry peers and thought leaders promoting adoption of smart ...
(Date:8/18/2015)... Research and Markets ( http://www.researchandmarkets.com/research/9dmm6l/global_biometric ) ... Biometric Authentication & Identification Market: Focus On Modality, ... report to their offering. ... is expected to grow at an estimated CAGR ... over $25 billion (approximately) by 2020 as per ...
(Date:8/12/2015)... CORAL SPRINGS, Florida , August 12, 2015 /PRNewswire/ ... globally, the pace of mobile payment innovation and advanced ... continues to replace the way consumers rely on using ... forges ahead with reinventing the future for payment services ... Inc. (NASDAQ: NXTD ), :  Google, Inc. (NASDAQ: ...
Breaking Biology News(10 mins):NXT-ID, Inc. Joins Smart Card Alliance and EMV Migration Forum 2NXT-ID, Inc. Joins Smart Card Alliance and EMV Migration Forum 3NXT-ID, Inc. Joins Smart Card Alliance and EMV Migration Forum 4Global Biometric Authentication & Identification Market 2015: Focus On Modality, Motility & Application - Estimation & Forecasts to 2020 for the $25 Billion Industry 2Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 2Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 3Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 4Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 5Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 6
... like hype from a late-night infomercial: It can twist ... could someday help you fend off disease! But ... several institutions including the U.S. Department of Energy,s Lawrence ... the cell,s protein-making machine, the ribosome, at key stages ...
... available in Spanish . , After corn ... looks something like slightly dampened cornmeal, though a somewhat darker ... grains with solubles" (WDGS), this byproduct is sometimes used as ... in Clay Center, Neb., are studying the pros and cons ...
... Researchers from the University of Iowa Roy J. ... that inhaled carbon black nanoparticles create a double source ... published online in the April 27 edition of the ... UI professor of internal medicine, was lead author of ...
Cached Biology News:Atomic-scale structures of ribosome could help improve antibiotics 2Atomic-scale structures of ribosome could help improve antibiotics 3Studies focus on feed ingredient's effects on levels of E. coli O157:H7 in cattle 2Carbon black nanoparticles can cause cell death 2
(Date:8/27/2015)... 27, 2015 The National Necrotizing Fasciitis ... life—were saved by doctors at Vanderbilt University Hospital in ... NovaBay Pharmaceuticals and Dr. John Crew , director ... Seton Medical Center in Daly City, CA. ... breakthrough approach, pioneered by Dr. Crew, that had previously ...
(Date:8/27/2015)... ... 27, 2015 , ... Inc. Magazine released its annual list of the 5,000 ... in growth for the three years through 2014. Being named to the Inc. 5000 ... in the country. , “We are thrilled to make the Inc. 5000 list ...
(Date:8/26/2015)... /PRNewswire/ - iCo Therapeutics ("iCo" or "the Company") (TSX-V: ... the quarter ended June 30, 2015. Amounts, unless ... presented under International Financial Reporting Standards ("IFRS"). ... our Oral Amp B program, rapidly advancing towards ... Andrew Rae , President & CEO of iCo ...
(Date:8/26/2015)... Intrexon Corporation (NYSE: XON ), a ... its previously announced public offering of common stock, including ... option to purchase an additional 731,707 shares of common ... share.  The exercise of the underwriters, option brought the ... Intrexon to 5,609,756 shares and increased the total gross ...
Breaking Biology Technology:Patient's Life and Eyes Saved from Gruesome Flesh-Eating Infection Consuming Her Face 2Patient's Life and Eyes Saved from Gruesome Flesh-Eating Infection Consuming Her Face 3iLab Solutions Named to 2015 Inc. 5000 List 2iLab Solutions Named to 2015 Inc. 5000 List 3iCo Therapeutics Announces Second Quarter 2015 Financial Results 2iCo Therapeutics Announces Second Quarter 2015 Financial Results 3Intrexon Announces Closing of $230 Million Public Offering of Common Stock including Full Exercise of Underwriters' Option to Purchase Additional Shares 2Intrexon Announces Closing of $230 Million Public Offering of Common Stock including Full Exercise of Underwriters' Option to Purchase Additional Shares 3Intrexon Announces Closing of $230 Million Public Offering of Common Stock including Full Exercise of Underwriters' Option to Purchase Additional Shares 4
... here is expanding to produce more trillions of beneficial ... clean up soil and groundwater, treat waste water, and ... its output this year from about 20,000 gallons a ... -- about 1.1 trillion per gallon. The production increase ...
... /PRNewswire/ -- US Oncology, Inc ., one ... to FORTUNE magazine,s Most Admired Companies list ... and Other category. This is the third time US Oncology has ... Most Admired Companies distinction, having been named to the list in ...
... the viability of Embryonic Stem Cells is an Illusion. Repair (Adult) ... treated all over the world, that it will be impossible for embryonic ... ever. , ... Bangkok (PRWEB) March 12, 2009 -- Don Margolis, the ...
Cached Biology Technology:Osprey Biotechnics: More Trillions of Good Bacteria 2US Oncology Named to FORTUNE Magazine's Most Admired Companies List for Third Time 2US Oncology Named to FORTUNE Magazine's Most Admired Companies List for Third Time 3Repair Stem Cell Institute Weighs in on Reversal of Embryonic Stem Cell Policy 2
Edited by Benjamin Lewin (1997) • This book gives an integrated account of the structure and function of genes in both prokaryotic organisms and is thoroughly up to date with the latest thinking...
... TOPO Cloning is the ... for cloning PCR products. ... Zero Blunt TOPO vectors ... activated with topoisomerase I. ...
...
Applications: ISH...
Biology Products: