Navigation Links
Prosthetic vein valve designed to direct blood flow shows promising pre-clinical results
Date:9/15/2008

et their symptoms rather than the cause. Damaged vein valves can sometimes be repaired, but when that isn't possible, some surgical options are available to replace deep venous valves, such as valve transplantation. However, replacing the valve with a prosthetic one is likely the better option because finding a suitable donor valve in one of the patient's legs can be difficult, according to Ku.

"Previous studies have shown that even if a donor valve is found, implanting it can cause significant trauma to the patient's leg," explained Ku, who has doctoral degrees in mechanical engineering and medicine. "To avoid these complications, other prosthetic vein valves have been designed, but most have demonstrated poor clinical potential for humans."

Ku and his collaborators believe the valve they have developed will overcome previous difficulties. The one-way flap is made of poly(vinyl alcohol) cryogel, a material patented by Georgia Tech in 1999. The material has many useful attributes, including its biocompatibility with body tissue because of its attraction to water; the ability to adjust its mechanical strength; flexibility comparable to that of natural body tissue; and composition of organic polymer, rather than silicone.

The researchers will begin conducting preclinical animal trials at Emory University in October to test the in vivo biocompatibility and performance of the prosthetic vein valve prototype in sheep. Sheep were chosen because their cardiovascular geometry and physiology are similar to those of humans.

In each animal trial, two prosthetic vein valves will be implanted by Milner. The researchers will test the biocompatibility and performance of the devices for four weeks, using imaging techniques to check that the valves remain in the proper location, are open and allow blood to pass through the vein.

The animal trials will be conducted after several years of optimizing the valve design
'/>"/>

Contact: Abby Vogel
avogel@gatech.edu
404-385-3364
Georgia Institute of Technology Research News
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. MIT aids creation of neural prosthetic devices
2. Thinking makes it so: Science extends reach of prosthetic arms
3. Portable electricity, life-like prosthetics on the way
4. When bivalves ruled the world
5. Endobronchial valve significantly improves emphysema
6. Book is the first high-resolution digital mouse brain atlas designed for Web applications
7. Specially-designed soils could help combat climate change
8. New, more direct pathways from outside the cell-to-cell nuclei discovered
9. 4,000 e-Books now available on ScienceDirect
10. Michael A. Betts, Seasoned Financial Services Executive, Joins CIC Board of Directors
11. Office of the Director of National Intelligence, CIO to Speak at Government Security Conference
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Prosthetic vein valve designed to direct blood flow shows promising pre-clinical results
(Date:1/22/2015)... /PRNewswire/ - Today, FindBiometrics, the leading source of biometrics industry news, ... website design. "When we launched FindBiometrics 12 years ... O,Neill , founder and CEO of FindBiometrics. "Now it,s maturing ... the key players on a very broad scale.  We are ...
(Date:1/22/2015)... 2015  A man-made form of insulin delivered by nasal ... in adults with mild cognitive impairment and Alzheimer,s disease ... at Wake Forest Baptist Medical Center. The ... cognitive impairment (MCI) or mild to moderate Alzheimer,s dementia ...
(Date:1/22/2015)... , January 22, 2015 , ... year  The European Patent Office to present a video ... British nominations to be featured: Christofer Toumazou and ... former finalists and winners of the Award   Starting ...
Breaking Biology News(10 mins):Identity Industry Leading Publication Debuts New Look As Biometrics Hit Mainstream 2Nasal Spray with Insulin Equivalent Shows Promise as Treatment for Adults with Mild Cognitive Impairment, Alzheimer's Dementia 2Nasal Spray with Insulin Equivalent Shows Promise as Treatment for Adults with Mild Cognitive Impairment, Alzheimer's Dementia 3Ten Years of the European Inventor Award: A Retrospective Look at the Inventors and Ideas That Have Changed Our Lives 2Ten Years of the European Inventor Award: A Retrospective Look at the Inventors and Ideas That Have Changed Our Lives 3
... and Zafer Iqbal, research professors at NJIT, were awarded ... arrays of nanoscale electrical probes. Their discovery may ... variation of electrical activity inside biological cells. ... technique that allows for an array of individual, vertically-oriented ...
... DUNES NATIONAL LAKESHORE, Ind. Native bees often small, ... stinging honeybees are quite discriminating about where they ... The study found that, overall, composition of a plant ... a bee community, which may seem counterintuitive at first, ...
... of California, Riverside have made a discovery in the ... drugs and explore novel strategies for treating seizures associated ... Americans. Neurons, the basic building blocks of the ... and chemical signaling. During epileptic seizures, which generally ...
Cached Biology News:Patent for arrays of nanoscale electrical probes awarded to NJIT today 2Picky pollinators: Native bees are selective about where they live and feed 2Picky pollinators: Native bees are selective about where they live and feed 3Picky pollinators: Native bees are selective about where they live and feed 4UC Riverside neuroscientists' discovery could bring relief to epilepsy sufferers 2
(Date:1/23/2015)... Biofertilizers stimulate microbial activities in soil. These microorganisms ... the activities in the soil or in the rhizosphere. ... stress on reducing environmental pollution and on reducing the ... segments the bio fertilizers market with analysis and forecasting ...
(Date:1/22/2015)...  Transwestern | RBJ today announces the firm brokered a long-term ... a leading biopharmaceutical company, at Two Ledgemont Center in ... Richards , president, and Brian Cohen , senior vice ... building at 95 Hayden Ave. Photo - ...
(Date:1/22/2015)... RI (PRWEB) January 22, 2015 Protocol ... , The growing team of brand-neutral, independent consultants, Protocol ... Philip Rogers explained that over the years, his company ... , Moroso, Town of Plainfield, as well as others. ...
(Date:1/22/2015)... 22, 2015 Controlled Substance Compliance Services ... helps companies check the legal requirements around using controlled ... China. , As their international operations expand and ... software solutions built as a result of the first ...
Breaking Biology Technology:Biofertilizers Market Expected to Reach $1,649.7 Million by 2019 - New Report By MarketsandMarkets 2Biofertilizers Market Expected to Reach $1,649.7 Million by 2019 - New Report By MarketsandMarkets 3Biofertilizers Market Expected to Reach $1,649.7 Million by 2019 - New Report By MarketsandMarkets 4Transwestern | RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Protocol Networks Brings Independent Technology Consulting to the Constitution State 2Global Compliance Service for Controlled Substances to Expand to China 2
... July 9 Abt Bio-Pharma Solutions, Inc.,(ABS), ... economic, and,strategic commercialization solutions, is pleased to ... and business strategy, has been promoted to,Executive ... succeeding Susan Windham-Bannister, who has been appointed,President ...
... Provides expertise in high-growth therapeutic areas to pharmaceutical and ... biotechnology companies ... the last year, BEVERLY HILLS, Calif., July 9 Worldwide Clinical,Trials, ... reached a milestone in establishing itself as a premier global,contract research organization ...
... July 9 Cepheid (Nasdaq:,CPHD) today announced ... on Healthcare Associated Infections, Fred Tenover, Ph.D., ... will serve as a liaison,with the Infection ... Infection (HAI) Consortium program., "The objective ...
Cached Biology Technology:Abt Bio-Pharma Solutions, Inc. Names Nandini Hadker as Executive Director, Succeeding Susan Windham-Bannister 2Abt Bio-Pharma Solutions, Inc. Names Nandini Hadker as Executive Director, Succeeding Susan Windham-Bannister 3Worldwide Clinical Trials Emerges as Leading Global Contract Research Organization 2Worldwide Clinical Trials Emerges as Leading Global Contract Research Organization 3Noted Molecular Epidemiologist Joins Cepheid to Head Healthcare Associated Infection Consortium Program 2Noted Molecular Epidemiologist Joins Cepheid to Head Healthcare Associated Infection Consortium Program 3
Mouse monoclonal [SH-A1] to S100 alpha ( Abpromise for all tested applications). entrezGeneID: 6271 SwissProtID: P23297...
This application changes sensitive keywords in an FCS file to remove patient information. It was contributed by Dr. David Miller....
Rat monoclonal [HK5.3] to B7 RP1 (Biotin) ( Abpromise for all tested applications). entrezGeneID: 23308 SwissProtID: O75144...
Zinc finger MYM-type protein 3 (Zinc finger protein 261) (DXS6673E protein). [Source:Uniprot/SWISSPROT;Acc:Q14202] Antigen: Recombinant Protein Epitope Signature Tag (PrEST)....
Biology Products: