Navigation Links
Prostate cancer spurs new nerves
Date:12/1/2008

Prostate cancer and perhaps other cancers promotes the growth of new nerves and the branching axons that carry their messages, a finding associated with more aggressive tumors, said researchers from Baylor College of Medicine in the first report of the phenomenon that appears today in the journal Clinical Cancer Research.

Previous research showed that prostate cancer follows the growth of nerves, but this is the first time that scientists have demonstrated that the tumors actually promote nerve growth.

"This is the first report of this phenomenon," said Dr. Gustavo Ayala, professor of pathology and urology at BCM and first author of the article. "It represents an important new target in prostate cancer treatment, as prostate cancers are more aggressive when neurogenesis is present."

Ayala noted that this finding is comparable to the discovery of angiogenesis or the growth of new blood vessels. Both are part of the wound repair process.

"We also believe that axongenesis and neurogenesis is found not only in prostate cancer, but is potentially a more global phenomenon, particularly relating to those cancers that grow along nerve paths," said Ayala, also a researcher in the Dan L. Duncan Cancer Center at BCM.

Ayala and his colleagues studied the neurogenesis in tissue culture, in human tissues of patients who had had prostate cancer and compared to prostate tissues from patients who had died of other ailments. They calculated the density of nerves in human prostate tissues, including those with prostate cancer. They found that nerve density was considerably higher in patients with prostate cancer and in precancerous lesions. As part of the study, he used an entire prostate gland to reconstruct the prostate and enable scientists to see the growth of nerves and axons in three-dimensions, a computerized process that took substantial continuous computer processing.

He and his colleagues have even identi
'/>"/>

Contact: Glenna Picton
picton@bcm.edu
713-798-4710
Baylor College of Medicine
Source:Eurekalert

Page: 1 2

Related biology news :

1. Genetic risk factors may tailor prostate cancer screening approaches
2. Height linked to risk of prostate cancer development and progression
3. Why a common treatment for prostate cancer ultimately fails
4. Exposure to Agent Orange linked to prostate cancer in Vietnam veterans
5. UCLA researchers locate and image prostate cancer as it spreads to lymph nodes
6. Prostate cancer vaccines more effective with hormone therapy
7. Counting tumor cells in blood predicts treatment benefit in prostate cancer
8. Urologists identify 7 biomarkers that may help pinpoint prostate cancer recurrence
9. Certain form of tomatoes could be key to prostate cancer prevention
10. Estrogen helps drive distinct, aggressive form of prostate cancer
11. Genes may play role in risk assessment for prostate cancer among Hispanics and caucasians
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... --  LaunchKey , the first decentralized mobile authentication and ... Things era, today announced the close of $3 million ... by Metamorphic Ventures with participation from ENIAC Ventures, Crosslink ... LaunchKey has raised $4 million to date, and will ... bring LaunchKey to market in 2015. LaunchKey ...
(Date:12/17/2014)... Dec. 15, 2014  HITLAB SM announced ... (GCP) audit to confirm its adherence to current ... accomplishment enables HITLAB to conduct regulated smart device ... principles for patient safety and research quality. ... access, quality, and delivery with innovative technology," said ...
(Date:12/17/2014)... , Dec. 16, 2014  Automation is ... this more evident than at international borders. Over ... document scanners have allowed veteran travelers to self ... Passport Control (APC) Kiosks at an increasing number ... globe. According to Maxine ...
Breaking Biology News(10 mins):LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 3HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2
... embryo formation in the lowly fruit fly, a little ... to a study in the Oct. 14 Developmental ... While the fundamentals of this tiny bug,s reproductive ... quite a bit to humans. That,s because the study ...
... why people who eat more fruit and vegetables may gain ... that a fragment released from pectin, found in all fruits ... 3 (Gal3), a protein that plays a role in all ... effects of foods are based on population studies," says Professor ...
... TALLAHASSEE, Fla. -- In a groundbreaking study led by ... have discovered that as embryonic stem cells turn into ... the order in which DNA is replicated and reorganized. ... stem cell biologists, enabling them to better understand the ...
Cached Biology News:Scientists trace molecular origin of proportional development 2Scientists trace molecular origin of proportional development 3Pectin power 2Landmark study unlocks stem cell, DNA secrets to speed therapies 2Landmark study unlocks stem cell, DNA secrets to speed therapies 3
(Date:12/24/2014)... , Dec. 23, 2014 Vermillion, ... focused on gynecologic disease, announced today that investors ... , Birchview Fund LLC and several Vermillion directors ... unregistered shares of Vermillion,s common stock and warrants ... in a private placement.  Under ...
(Date:12/24/2014)... NEW YORK , Dec. 23, 2014 /PRNewswire/ ... study of mazindol in children with attention deficit/hyperactivity disorder ... December 2014 . The paper, titled ... attention deficit/hyperactivity disorder" ( Konofal et al, ... eCollection 2014 ) shows that mazindol might be ...
(Date:12/22/2014)... , Dec. 22, 2014  Alternative Energy ... that it has signed a letter of intent ... has developed and patented a nanotechnology-based development platform ... products that enable rapid on-site collection and testing ... and health issues in an immediate, non-invasive and ...
(Date:12/22/2014)... Illinois (PRWEB) December 22, 2014 ITRA ... tenants and occupiers of commercial real estate, has further ... new offices in Perth and Brisbane, Western Australia, reports ... of directors. , ITRA Global / ACORPP (Australian ... totally independent consultancy company providing property services to a ...
Breaking Biology Technology:Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 2Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 3Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 4Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 5Redefining ADHD: A New Approach & A Shift of Paradigm in ADHD Therapeutics 2Redefining ADHD: A New Approach & A Shift of Paradigm in ADHD Therapeutics 3ALNE Announces Intention To Acquire BioTechPharma 2ITRA Global Continues International Expansion in Perth and Brisbane, Australia 2
... ... ... -- The American Medical Writers Association named medical writer, Rita Buckley, Writer/Owner of ... in Medical Communication. She received the awards for The Lehman Series Expert Panel on ...
... June 11, 2010 Researchers at Texas A&M University College ... first with the successful delivery of a foal using oocytes ... world. The delivery of the foal highlights Texas A&M,s long ... a great experience for the owner of the new foal., ...
... world,s smallest chess board about the diameter of ... winners in this year,s design contest for, respectively, novel ... Laboratories in mid May. The two winning teams ... one of the most advanced in the world. ...
Cached Biology Technology:Medical Writer Rita Buckley Wins Awards for Excellence in Medical Communication 2Medical Writer Rita Buckley Wins Awards for Excellence in Medical Communication 3Texas A&M veterinary researchers achieve cloning first 2Texas A&M veterinary researchers achieve cloning first 3Texas Tech, U of Utah win Sandia microdevice competition 2Texas Tech, U of Utah win Sandia microdevice competition 3Texas Tech, U of Utah win Sandia microdevice competition 4
... Microarrays designed for RNA aptamer screening ... flexible and powerful Paraflo microfluidic on-chip synthesis ... can be synthesized on-chip and LC Sciences ... These microarrays are available as part of ...
... LX80L is an extension of Parkers MX80 family ... compact cross-section. LX80L bolt hole patterns mimic the ... units and all accessory brackets to build multi-axis ... travel to 750 mm , Accelerations to 5 ...
... is compatible with BioTeks microplate washers, ... of use and walkaway automation are ... When used with the ELx405 washer ... Bio-Stacks small footprint fits easily in ...
... the use of small interfering RNA (siRNA) ... RNA interference (RNAi) pathway have generated tremendous ... fields. siRNA for experimental use can be ... and then transfected into the target cells ...
Biology Products: