Navigation Links
Prostate Cancer Foundation announces new urine test for prostate cancer available
Date:9/26/2013

ine health screening measure for men of a certain age. What everyone does agree upon is the need for better markers of prostate cancer. To date there are no perfect biomarkers that identify only high-risk prostate cancer. But each year progress is made toward such a goal. Today, the University of Michigan's Department of Pathology MLabs will begin offering the MiPS urine test that is ultra specific for prostate cancer. The MiPS test scans urine samples for two molecular markers that are distinct to prostate cancer. One marker is a snippet of RNA made from a gene (PCA3) that is overactive in 95 percent of all prostate cancers. The second marker is RNA that is made only when two genes (TMPRSS2 and ERG) abnormally fuse. The presence of this fusion RNA in a man's urine is ultra specific for prostate cancer.

An ultra-specific test for prostate cancer

  • Dr. Scott Tomlins, MD, PhD, is an assistant professor of pathology and urology at the University of Michigan and a Safeway-Prostate Cancer Foundation Young Investigator. Tomlins co-discovered what is now commonly known as the TMPRSS2:ERG fusion. "The evidence shows that if TMPRSS2:ERG RNA is detectable at high levels in urine, a man likely has prostate cancer, whether or not his biopsy is positive for cancer," said Tomlins. (Because biopsies typically sample less than 1 percent of the prostate gland, cancers can be missed, even high-grade cancers.)

    A commercial urine test (PROGENSA PCA3) for PCA3, developed and marketed by the California-based biotech company Gen-Probe, gained FDA approval in 2012 for use in men who are considering repeat biopsy after an initially negative result. While a welcome development, research shows that the new urine test offered by MLabs that measures both PCA3 and TMPRSS2:ERG should improve a doctor's ability to stratify men suspected of having prostate cancer. In a study published in Science Translational Medicine, Tomlins and colleagues
    '/>"/>


Contact: Rebecca Levine
rlevine@pcf.org
310-570-4727
Prostate Cancer Foundation
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Wistar receives $1.5 million Department of Defense grant to ready prostate drug for clinical use
2. Study highlights possible new approach to prostate cancer treatment
3. Which Prostate Cancers Really Need Treatment?
4. Using big data to identify prostate cancers and best treatments
5. UCI chemists devise inexpensive, accurate way to detect prostate cancer
6. PARP inhibitor shows activity in pancreatic, prostate cancers among patients carrying BRCA mutations
7. Soy and tomato combo may be effective in preventing prostate cancer
8. Particular DNA changes linked with prostate cancer development and lethality
9. Nonsurgical treatment turns back the clock, shrinks enlarged prostate
10. First genetic factor in prostate cancer prognosis identified
11. Landmark study describes prostate cancer metastasis switch
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... , Europe,s most ... Patent Office to present a video retrospective of the most exciting ... Christofer Toumazou and Sophie Wilson   ... the Award   Starting on 22 January 2015 on   ...
(Date:1/22/2015)... Jan. 22, 2015 Infinisource has launched its new NXG ... model. The G2 sets a higher standard for collecting attendance ... management solution. With plug-and-play installation, touch screen interface and seamless ... a robust time collection solution for the small to mid-size ...
(Date:12/22/2014)... 22, 2014 Research and Markets ( ... "The Global Watermarking and Fingerprinting Markets" ... http://photos.prnewswire.com/prnh/20130307/600769 This insight provides ... and fingerprinting markets. Watermarking aims to control and ...
Breaking Biology News(10 mins):Ten Years of the European Inventor Award: A Retrospective Look at the Inventors and Ideas That Have Changed Our Lives 2Ten Years of the European Inventor Award: A Retrospective Look at the Inventors and Ideas That Have Changed Our Lives 3Infinisource's NXG series sets new time clock standard 2The Global Watermarking and Fingerprinting Markets 2
... 2013 -- American Associates, Ben-Gurion University of the Negev (AABGU) ... late Dr. Jordan Baruch, to fund stem cell research at ... The Jordan Baruch Stem Cell Research Fund was dedicated at ... Baruch and 20 members of her extended family. "Jordan ...
... new study has found that tamoxifen, a well-known breast ... mouse model of Duchenne muscular dystrophy (DMD). At present, ... the symptoms in boys with DMD, a debilitating muscular ... and cardiac impairments, paralysis, and premature death. This study ...
... TORONTO, Jan 14, 2013Taking a vitamin D supplement and drinking ... how much vitamin D is in a child,s body, new ... than even skin colour and exposure to the sun, according ... Michael,s Hospital. "Early childhood is a critical stage in ...
Cached Biology News:Ben-Gurion U. establishes stem cell research fund in honor of inventor Jordan Baruch 2Tamoxifen ameliorates symptoms of Duchenne muscular dystrophy 2Supplements and cow's milk play biggest roles in determining vitamin D levels in children 2
(Date:1/22/2015)... RI (PRWEB) January 22, 2015 Protocol ... , The growing team of brand-neutral, independent consultants, Protocol ... Philip Rogers explained that over the years, his company ... , Moroso, Town of Plainfield, as well as others. ...
(Date:1/22/2015)... January 22, 2015 zFlo Motion , ... to announce an exciting product from a new partner. ... solutions over the past 15 years, with offerings in the ... their 3D IMU system (inertial measurement unit), iSen, is opening ...
(Date:1/22/2015)... Selexis SA, a serial innovation company ... (RCBs) used for drug discovery to commercial manufacturing, announced ... Next-Generation Sequencing (NGS) data packages. The NGS ... by ensuring the integrity of the gene, validation of ...
(Date:1/22/2015)...   Cypher Genomics, Inc., the leading genome ... SQNM ), the leading molecular diagnostics company, today ... prenatal tests (NIPT). Through this agreement, Sequenom will ... advance analysis of clinically-relevant fetal sub-chromosomal variants detected ...
Breaking Biology Technology:Protocol Networks Brings Independent Technology Consulting to the Constitution State 23D Motion Capture Just Got Easy 2Selexis Generated Research Cell Banks Now Fully Sequenced Using Next-Generation Sequencing 2Cypher Genomics and Sequenom Announce Development Agreement 2Cypher Genomics and Sequenom Announce Development Agreement 3Cypher Genomics and Sequenom Announce Development Agreement 4
... relying on existing telecommunications satellites, has put a second satellite ... weather information clients. , ,Last September, Loral Skynet ... and rerouted its customers to Telstar 5 and 6. The ... Birch, data services product manager for Weather Central, said his ...
... startups, biotech , ,Entrepreneurship, nanotechnology and biomedical engineering ... in Madison and Milwaukee, giving substance to what Wisconsin ... , , Tips for Entrepreneurs , ,Established entrepreneurs ... Entrepreneurs Conference , which runs June 1-2 at the ...
... MILWAUKEE Advocates of Windows and open-source software vied ... presentation of Wednesdays session of the ITEC conference in ... Labs , said that open-source software provides a technically ... companies that want a single, obvious place to turn ...
Cached Biology Technology:Doyles Entrepreneurs and Research week nears 2Doyles Entrepreneurs and Research week nears 3Linux and Windows duke it out at ITEC 2Linux and Windows duke it out at ITEC 3
... for high-yield protein expression ,The ... a high-yielding clone of Sf9 cells. Pre-adapted ... Cell Medium, these cells are recommended for ... baculovirus infection or transfection of appropriate vectors. ...
Mouse monoclonal antibody raised against a partial recombinant VRK2. NCBI Entrez Gene ID = VRK2...
Mouse monoclonal antibody raised against a full length recombinant SCGB3A2. NCBI Entrez Gene ID = SCGB3A2...
96-well format (For processing samples on microplate-size MALDI target plates such as those from Bruker, Shimadzu, Thermo, and PerkinElmer) Packaging: 2 / pack...
Biology Products: