Navigation Links
Prostate Cancer Foundation announces new urine test for prostate cancer available
Date:9/26/2013

ine health screening measure for men of a certain age. What everyone does agree upon is the need for better markers of prostate cancer. To date there are no perfect biomarkers that identify only high-risk prostate cancer. But each year progress is made toward such a goal. Today, the University of Michigan's Department of Pathology MLabs will begin offering the MiPS urine test that is ultra specific for prostate cancer. The MiPS test scans urine samples for two molecular markers that are distinct to prostate cancer. One marker is a snippet of RNA made from a gene (PCA3) that is overactive in 95 percent of all prostate cancers. The second marker is RNA that is made only when two genes (TMPRSS2 and ERG) abnormally fuse. The presence of this fusion RNA in a man's urine is ultra specific for prostate cancer.

An ultra-specific test for prostate cancer

  • Dr. Scott Tomlins, MD, PhD, is an assistant professor of pathology and urology at the University of Michigan and a Safeway-Prostate Cancer Foundation Young Investigator. Tomlins co-discovered what is now commonly known as the TMPRSS2:ERG fusion. "The evidence shows that if TMPRSS2:ERG RNA is detectable at high levels in urine, a man likely has prostate cancer, whether or not his biopsy is positive for cancer," said Tomlins. (Because biopsies typically sample less than 1 percent of the prostate gland, cancers can be missed, even high-grade cancers.)

    A commercial urine test (PROGENSA PCA3) for PCA3, developed and marketed by the California-based biotech company Gen-Probe, gained FDA approval in 2012 for use in men who are considering repeat biopsy after an initially negative result. While a welcome development, research shows that the new urine test offered by MLabs that measures both PCA3 and TMPRSS2:ERG should improve a doctor's ability to stratify men suspected of having prostate cancer. In a study published in Science Translational Medicine, Tomlins and colleagues
    '/>"/>


Contact: Rebecca Levine
rlevine@pcf.org
310-570-4727
Prostate Cancer Foundation
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Wistar receives $1.5 million Department of Defense grant to ready prostate drug for clinical use
2. Study highlights possible new approach to prostate cancer treatment
3. Which Prostate Cancers Really Need Treatment?
4. Using big data to identify prostate cancers and best treatments
5. UCI chemists devise inexpensive, accurate way to detect prostate cancer
6. PARP inhibitor shows activity in pancreatic, prostate cancers among patients carrying BRCA mutations
7. Soy and tomato combo may be effective in preventing prostate cancer
8. Particular DNA changes linked with prostate cancer development and lethality
9. Nonsurgical treatment turns back the clock, shrinks enlarged prostate
10. First genetic factor in prostate cancer prognosis identified
11. Landmark study describes prostate cancer metastasis switch
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/14/2015)... YORK , April 14, 2015  HYPR ... IDentity Online (FIDO ® ) Alliance tm , ... specifications. FIDO members commit to share technology and ... methods that are interoperable, more secure and private, ... enable biometric identity verification that protects sensitive user ...
(Date:4/13/2015)... NEW YORK , April 13, 2015 /PRNewswire/ ... study by TechSci Research, "Global Biometrics Market Forecast & ... to register a CAGR of around 14% till ... various governments for large scale implementation and review ... technology and launch of new products with greater ...
(Date:4/10/2015)... 2015 Research and Markets ( ... "Security Competitive Profiles - NEC" report to their ... NEC will continue to supply a range of IT ... a company focus on the development of a Big ... opportunities in the Asia-Pacific region ...
Breaking Biology News(10 mins):HYPR Corp. Joins the FIDO Alliance 2HYPR Corp. Joins the FIDO Alliance 3Global Biometrics Market to Cross US$ 21 Billion by 2020: TechSci Research 2NEC Security Competitive Profile 2015 2
... from the melting Arctic ice cap told Jeff Chanton and ... there is a release of methane, a powerful greenhouse gas ... how much, said Chanton, the John W. Winchester Professor of ... whose findings were published in the respected journal Nature ...
... PORTOLA VALLEY, Calif., June 18, 2012 Spectros Corporation ... for viewing real-time patient results on T-Stat white light ... healthcare by improving patient monitoring and decreasing the delayed ... awaited an easy and simple approach to remote monitoring ...
... of surfaces in hotel rooms finds television remotes to ... items on housekeeping carts carry the potential to cross-contaminate ... the findings today at the 2012 General Meeting of ... obligation to provide their guests with a safe and ...
Cached Biology News:Study: Seeking Arctic methane has serious implications for Florida coastline 2Spectros Launches OnCall Wireless Remote Access for T-Stat 2The most contaminated surfaces in hotel rooms 2
(Date:5/28/2015)... 28, 2015 Research ... addition of Jain PharmaBiotech,s new report  "Alzheimer ...  to their offering.       (Logo: ... challenge in management. With nearly 8 million ... major markets of the world and anticipated ...
(Date:5/28/2015)... , May 28, 2015  Quest Diagnostics Incorporated (NYSE: ... information services, announced that it is scheduled to speak ... York.  Steve Rusckowski , the company,s President and ... point strategy.  The presentation is scheduled for Tuesday, June ... The presentation will be webcast live during the conference ...
(Date:5/28/2015)... 2015 Research and Markets( http://www.researchandmarkets.com/research/26qndf/nanobiotechnology ... PharmaBiotech,s new report "Nanobiotechnology Applications, Markets ... An increasing use of nanobiotechnology by ... Nanotechnology will be applied at all stages ... optimal delivery to diagnostic applications in clinical ...
(Date:5/28/2015)... , May 27, 2015 Research ... of Jain PharmaBiotech,s new report "Cell Therapy ... offering. This report describes and evaluates ... started to play an important role in the ... replacing the old fashioned bone marrow transplants. Role ...
Breaking Biology Technology:Global Alzheimer Disease Report 2015-2024 - New Drugs, Markets and Companies 2Global Alzheimer Disease Report 2015-2024 - New Drugs, Markets and Companies 3Quest Diagnostics to Speak at the Jefferies 2015 Global Healthcare Conference 2Global Nanobiotechnology Market 2015-2024 - Applications, Markets and Companies 2Global Nanobiotechnology Market 2015-2024 - Applications, Markets and Companies 3Global Cell Therapy Market 2015-2020 - Technologies, Markets and Companies 2
... MOUNTAIN VIEW, Calif., Oct. 14 Clontech Laboratories,Inc., ... the three,winners of the 2008 Nobel Prize in ... Tsien, for the discovery and development of the ... related fluorescent proteins.,The application of fluorescent proteins as ...
... America, Inc. and its,subsidiary Sysmex Canada, Inc. today ... from MOLIS WAM to Sysmex WAM. The new,name ... Sysmex brand,architecture., "Sysmex WAM is one of ... the hematology automation systems market today," explains Ralph,Taylor, ...
... Solos Endoscopy, Inc. (OTC,Pink Sheets: SNDY) is pleased ... to upgrade its status on the Pinksheets Electronic OTC ... in the process,of completing their Issuer Information Statement, which ... expects to have its status,upgraded by the end of ...
Cached Biology Technology:Clontech Laboratories, Inc. Recognizes the 2008 Winners of the Nobel Prize in Chemistry 2Solos Endoscopy, Inc. in Final Stages to Upgrade Pink Sheet Status from Limited to Current Information 2
... Ultrasonic Nebulizers are available in two product models ... these two models is that the 6000AT+ includes ... a drier aerosol for improved detection limits and ... for a range of elements by 10-40 times. ...
... Cetac Ultrasonic Nebulizers are available in two product ... between these two models is that the 6000AT+ ... create a drier aerosol for improved detection limits ... limits for a range of elements by 10-40 ...
... from Thermus aquaticus (strain YT1) is ... then highly purified to produce Taq ... the amplification and sequence testing of ... the Taq DNA polymerase has been ...
Request Info...
Biology Products: