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Promising new compound for treating stroke
Date:2/21/2012

number of potent compounds over a long period of time," recounts Anders Bach. He adds that scientists have committed many resources to finding out exactly how the compounds bind to PSD-95 using for example sophisticated biophysical methods. This has resulted in detailed understanding of the molecular mechanisms that cause the high level of activity.

Anders Bach hopes that the new compound can form the basis for a new drug on the global market, but he emphasises that such a process is long and complicated:

"Although we are very satisfied with the new results in terms of the possible treatment of brain damage due to stroke, many things can go wrong in the long drug development process. So even though the compound binds effectively in laboratory studies and shows promising biological activity in animal models, we will still have many challenges to overcome," concludes Anders Bach.

The PSD-95 protein is also involved in chronic pain as well as Alzheimer 's disease so the new compound may also prove interesting to examine in connection with other conditions.


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Contact: Anders Bach
anba@farma.ku.dk
(45) 40-32-08-06
University of Copenhagen
Source:Eurekalert

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