Navigation Links
Promising T cell therapy
Date:6/17/2014

This news release is available in German.

The cells of the human immune system are created from special stem cells in the bone marrow. In diseases affecting the bone marrow, such as leukemia, the degenerate cells must be destroyed using radiation or chemotherapy. Subsequently, the hematopoietic system has to be replaced with stem cells from the blood of a healthy donor. Because of the resulting temporary weakening of the immune system, patients are more exposed to viruses that would normally be warded off.

The cytomegalovirus (CMV), which can cause serious damage to lungs or liver in persons with a weakened defense, poses a major clinical problem. In healthy human beings, a CMV infection will usually not produce any symptoms, since the virus is kept at bay by specific immune cells. In their work, the scientists were able to demonstrate that the transfer of just a few specific immune cells is sufficient to protect the recipient with the weakened immune system against infections. To do this, they used T cells that can recognize and kill specific pathogens.

Tested in an animal model

Dr. Christian Stemberger, first author of the study, and his colleagues, first isolated T cells from the blood of healthy donor mice. These immune cells were directed against molecular elements of a bacterial species which normally causes severe infections in animals. The T cells were then transferred to recipient mice that, due to a genetic modification, could no longer produce immune cells of their own similarly to patients suffering from leukemia.

Following the T cell transfer, the researchers infected the treated recipient mice with the bacteria. The results showed that the animals now have effective immune protection against the pathogens, preventing th
'/>"/>

Contact: Vera Siegler
vera.siegler@tum.de
49-892-892-2731
Technische Universitaet Muenchen
Source:Eurekalert

Page: 1 2

Related biology news :

1. Promising discovery in the fight against antibiotic-resistant bacteria
2. Penn team identifies promising new target for gum disease treatment
3. New method yields potent, renewable human stem cells with promising therapeutic properties
4. Promising news for solar fuels from Berkeley Lab researchers at JCAP
5. Dartmouth researchers find promising results with local hyperthermia of tumors
6. New biological scaffold offers promising foundation for engineered tissues
7. Caltech-developed method for delivering HIV-fighting antibodies proven even more promising
8. Promising class of antibiotics discovered for treatment of drug-resistant tuberculosis
9. Scientists develop promising drug candidates for pain, addiction
10. New gene therapy proves promising as hemophilia treatment
11. T cell immunotherapy: Promising results in children and adults with leukemia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2014)... Antonio Life Sciences Institute (SALSI), a joint venture between ... The University of Texas Health Science Center at San ... Pilot Program. The winners, Emily Boice from UTSA and ... $25,000 for their project titled, "Novel engineered ferritins for ... , Boice and Huang,s research is focused on finding ...
(Date:7/30/2014)... be as simple as inserting a medicated, disappearing fabric ... bioengineers have discovered a potentially faster way to deliver ... Their method spins the drug into silk-like fibers that ... doses of the drug than possible with other topical ... offer women a potentially more effective, discreet way to ...
(Date:7/30/2014)... out how to create colors, nature had already perfected ... many different hues, for example. Now scientists are tapping ... way to make colored plastics. Their paper on using ... rather than dyes, to produce color appears in ... Asger Mortensen, Anders Kristensen and colleagues point out that ...
Breaking Biology News(10 mins):Dissolvable fabric loaded with medicine might offer faster protection against HIV 2Dissolvable fabric loaded with medicine might offer faster protection against HIV 3
... release is available in German . ... in the atmosphere where it contributes to global warming. The ... as forests, grasslands and peat-lands. Stimulating this "free service" of ... immediately available ways of reducing climate change. However, new greenhouse ...
... inventoried an astonishing abundance, diversity and distribution of deep sea ... manage a living in a frigid black world down to ... Revealed via deep-towed cameras, sonar and other vanguard technologies, animals ... 17,650, a diverse collection of species ranging from crabs to ...
... MA November 23, 2009 Agios Pharmaceuticals today ... time, that the mutated IDH1 gene has a novel ... This breakthrough discovery shows that the mutated form of ... to the formation and malignant progression of gliomas, the ...
Cached Biology News:Intensive land management leaves Europe without carbon sinks 2Beyond sunlight: Explorers census 17,650 ocean species between edge of darkness and black abyss 2Beyond sunlight: Explorers census 17,650 ocean species between edge of darkness and black abyss 3Beyond sunlight: Explorers census 17,650 ocean species between edge of darkness and black abyss 4Beyond sunlight: Explorers census 17,650 ocean species between edge of darkness and black abyss 5Beyond sunlight: Explorers census 17,650 ocean species between edge of darkness and black abyss 6Beyond sunlight: Explorers census 17,650 ocean species between edge of darkness and black abyss 7Beyond sunlight: Explorers census 17,650 ocean species between edge of darkness and black abyss 8Beyond sunlight: Explorers census 17,650 ocean species between edge of darkness and black abyss 9Cancer metabolism discovery uncovers new role of IDH1 gene mutation in brain cancer 2Cancer metabolism discovery uncovers new role of IDH1 gene mutation in brain cancer 3Cancer metabolism discovery uncovers new role of IDH1 gene mutation in brain cancer 4
(Date:7/31/2014)... , July 31, 2014 Research and ... "Global Genomics Market 2014-2018" report to their offering. ... Genomics is the study of the genetic material or ... a strong basis for the discovery and development of ... diseases or health conditions. Genomics is supported by three ...
(Date:7/31/2014)... Senomyx , Inc. (NASDAQ: ... taste science technologies to discover, develop, and commercialize ... ingredient supply industries, today reported financial results for ... second quarter with $33.6 million in cash and ... past quarter Senomyx achieved another important milestone with ...
(Date:7/31/2014)... SHENZHEN, China , July 31, 2014 /PRNewswire/ ... of an Irys™System by BGI , ... to enable comprehensive exploration of human structural variation (SV) ... of interest, including those where no reference exists. In ... new methods for multiplexing on the Irys System, enabling ...
(Date:7/31/2014)... Rancho BioSciences , the scientific ... Array Suite with tranSMART . Scientists that ... send data in tranSMART to Array Suite for further ... tranSMART including the new 1.2 release. Array Suite ... for the analysis of high dimensional quantification data, including ...
Breaking Biology Technology:Global Genomics Market 2014-2018: Key Vendors are F. Hoffmann-La Roche, Life Technologies, Qiagen and Illumina 2SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 2SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 3SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 4SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 5SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 6SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 7SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 8SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 9SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 10SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 11SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 12SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 13SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 14SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 15SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 16BioNano Genomics Announces the Purchase of the Irys System by BGI 2BioNano Genomics Announces the Purchase of the Irys System by BGI 3BioNano Genomics Announces the Purchase of the Irys System by BGI 4Rancho BioSciences, in Partnership with Omicsoft, have Integrated Array Suite with tranSMART 2Rancho BioSciences, in Partnership with Omicsoft, have Integrated Array Suite with tranSMART 3
... FORTUNE,S 100 Fastest-Growing Companies, List -- SHANGHAI, Aug. 26 /PRNewswire-Asia-FirstCall/ -- ... ... ... = ,; var first_result; // Results are keyed by longUrl, so we need to grab the ...
... Hikma - Half Year Results Interviews With CEO and CFO -- LONDON, August 26, 2010 ... ... ... ,; var first_result; // Results are keyed by longUrl, so we need to grab the first one. ...
... bag of potato chips or pop in a DVD, you,re probably ... soap. Sputter deposition is an industrial process used since the ... various backings, like the metallic coating on potato chip bags, the ... Mostly, the process works very well. In a vacuum chamber filled ...
Cached Biology Technology:China-Biotics Ranked Number 62 on FORTUNE'S 100 Fastest-Growing Companies' List 2China-Biotics Ranked Number 62 on FORTUNE'S 100 Fastest-Growing Companies' List 3China-Biotics Ranked Number 62 on FORTUNE'S 100 Fastest-Growing Companies' List 4China-Biotics Ranked Number 62 on FORTUNE'S 100 Fastest-Growing Companies' List 5China-Biotics Ranked Number 62 on FORTUNE'S 100 Fastest-Growing Companies' List 6China-Biotics Ranked Number 62 on FORTUNE'S 100 Fastest-Growing Companies' List 7Hikma - Half Year Results Interviews With CEO and CFO 2Hikma - Half Year Results Interviews With CEO and CFO 3Hikma - Half Year Results Interviews With CEO and CFO 4Hikma - Half Year Results Interviews With CEO and CFO 5Trouble with sputter? Blame giant nanoparticles 2Trouble with sputter? Blame giant nanoparticles 3
casein kinase 2, alpha 1 polypeptide, transcript variant 2, mRNA (cDNA clone MGC:15232 IMAGE:4121882), complete cds...
...
UV LAMP 300 NM 8W T5, 1 EA. Category: Nucleid Acid Detection Systems....
MOUSE ANTI S. MUTANS PEPTIDOGLYCAN...
Biology Products: