Navigation Links
Promising 3-year data: Saving limbs with drug-eluting stents
Date:3/10/2009

SAN DIEGO, Calif. (March 10, 2009)Attempts to treat critical limb ischemia in peripheral arterial disease (PAD) patients with below-the-knee angioplasty are still thwarted by restenosis (the re-narrowing of the artery at the site of angioplasty or stenting), the need for repeat treatments and the continued progression of atherosclerotic disease, leading to tissue death (gangrene) and amputation. Interventional radiologists have been studying a potential solutionthe use of drug-eluting stentsand have found that these types of stents lessened the rate of repeat procedures to open these small arteries, according to results presented at the Society of Interventional Radiology's 34th Annual Scientific Meeting.

"This is encouraging news for PAD patients with critical limb ischemia. The smaller blood vessels below the knee are more difficult to treat due to their size (3 millimeters) and are more prone to reclog than larger vessels. The use of drug-eluting stents in the tiny infrapopliteal arteries of the leg may significantly impact their care," said Dimitris Karnabatidis, M.D., assistant professor of interventional radiology at Patras University Hospital in Rion, Greece. "Drug-eluting (or drug-coated) stents have emerged as a potential solution to the limitations of endovascular treatment of PAD patients with critical limb ischemia," he added. An interventional radiologist performs a balloon angioplasty to open a clogged blood vessel and then places a drug-eluting stent in that artery. The stent acts as scaffolding to hold the narrowed artery open. Drug-eluting stents slowly release a drug for several weeks to block cell proliferation or regrowth, thus inhibiting restenosis.

Researchers from a single center studied 103 patients in a double-arm prospective registry who had critical limb ischemia and who underwent infrapopliteal revascularization with angioplasty and placement of either a drug-eluting stent (with sirolimus, an immunosuppressant drug
'/>"/>

Contact: Maryann Verrillo
mverrillo@SIRweb.org
703-460-5572
Society of Interventional Radiology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Research uncovers promising target to treat chronic abdominal pain
2. Landscape-scale treatment promising for slowing beetle spread
3. Promising new drug being evaluated as possible treatment option for fragile X syndrome
4. Researchers identify promising gene target for neuroblastoma therapy
5. UCR researchers propose minocycline as a promising drug for patients with Fragile X syndrome
6. Prosthetic vein valve designed to direct blood flow shows promising pre-clinical results
7. Promising new treatment option for women with recurrent ovarian cancer
8. Immunotherapy in high-risk pediatric sarcomas shows promising response
9. New treatment approach promising for lymphoma patients in the developing world
10. UIC researchers make promising finding in severe lung disease
11. Biodesigns Rittmann offers promising perspectives on societys energy challenge
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... species of fish, according to a new study ... tested fish anti-predator behaviour. , Three-spined sticklebacks ... when exposed to additional noise, whereas no effects ... author Dr Irene Voellmy of Bristol,s School of ... environments have increased substantially during the last few ...
(Date:7/24/2014)... sticky research out of York University shows a surprisingly ... toxic grass fungus: moose saliva (yes moose saliva). ... "Ungulate saliva inhibits a grassendophyte mutualism" shows that moose ... (which hosts a fungus called epichlo festucae that produces ... less toxicity. , "Plants have evolved defense mechanisms to ...
(Date:7/24/2014)... at The University of Texas Health Science Center at ... to help Harris County residents whose vision problems cannot ... with corrective lenses, many people with low vision can ... of low vision devices, such as telescopes, magnifiers and ... Iyer is using the three-year, $164,645 SightFirst grant from ...
Breaking Biology News(10 mins):Moose drool inhibits growth of toxic fungus: York U research 2UTHealth Dr. Bhavani Iyer awarded low vision grant 2
... DURHAM, N.H. The angel investor market in the first ... 30 percent market correction in the second half of 2008 ... $8.9 billion, an increase of 4.7 percent over the same ... at the University of New Hampshire. A ...
... Water channels exist not only in nature microscopical ... body, where they ensure that water can be transported through ... of Gothenburg, Sweden, have discovered that one type of the ... more stable , which may be significant in the treatment ...
... National Science Foundation (NSF) has selected a team of ... the new Sustainable Cities - People, Infrastructures and the ... is leading the project, which includes 20 U.S. universities, ... grant aims to bring together scientists from all over ...
Cached Biology News:Angel investor market stabilizes in first half of 2011, UNH Center for Venture Research finds 2Water channels in the body help cells remain in balance 2National Science Foundation selects University of Colorado Denver team to study city sustainability 2
(Date:7/24/2014)... worldwide rely on sophisticated equipment, trained personnel, and ... areas against terrorist attacks. A revolutionary new electronic ... make their job much easier. , The groundbreaking ... Tel Aviv University ,s School of Chemistry and ... the Herzliya company Tracense, picks up the scent ...
(Date:7/24/2014)... Yet, scientists are making progress in devising suitable ... approach relies on quantum dotsa kind of artificial ... A new study demonstrates that changing the coupling ... electrical impulses can help better control them. This ... as quantum information units, which would produce faster ...
(Date:7/24/2014)... to settle into equilibriuma state of unchanging balance ... of non-equilibrium conditions where new possibilities lie. Non-equilibrium ... such as temperature fluctuations, freezing and melting, or ... body temperature, airplanes to fly, and the Earth ... even though these conditions exist naturally and are ...
(Date:7/24/2014)... July 24, 2014 Research and Markets ... Genomics and Proteomics Analytical Instruments Market 2014-2018" report ... Genomics is the study of the ... of the structure and functions of proteomes or sets ... and technology. Genomics involves the mapping of genes and ...
Breaking Biology Technology:Nano-sized chip 'sniffs out' explosives far better than trained dogs 2New approach to form non-equilibrium structures 2Global Genomics and Proteomics Analytical Instruments Market 2014-2018: Key Vendors are Agilent, Bio-Rad , F. Hoffmann, La Roche, Illumina, PerkinElmer and Thermo Fisher Scientific 2
... AGREEMENT COVERS MARROWXPRESS(TM) IN KEY GLOBAL MARKETS, ... KOOL ), a leading supplier of innovative ... cells, said today it has signed,a distribution agreement ... used for isolating stem cells from bone,marrow. The ...
... MINNETONKA, Minn., Sept. 9 For the second ... in clinical study management systems, has been recognized ... fastest growing private,organizations. With consistently strong growth over ... growing company in the Twin Cities,metro area, and ...
... of Cervical Cancer Prevention: What Do We Need to Do, Now ... ... HPV Vaccine Era, CHICAGO, Sept. 9 The Society of ... 12-13,2008 at the Hotel SAX in Chicago, IL. Approximately 50 key ...
Cached Biology Technology:ThermoGenesis Announces Distribution Agreement for Bone Marrow Stem Cell Device 2ThermoGenesis Announces Distribution Agreement for Bone Marrow Stem Cell Device 3ThermoGenesis Announces Distribution Agreement for Bone Marrow Stem Cell Device 4MedNet Solutions Again Recognized as one of the Fastest Growing US Companies 2Society of Gynecologic Oncologists to Host Cervical Cancer Prevention Forum 2Society of Gynecologic Oncologists to Host Cervical Cancer Prevention Forum 3