Navigation Links
Promiscuous enzymes may be recruited to aid industry, medical fields
Date:3/3/2013

COLLEGE STATION Enzymes in cells normally perform only one job, but a new study by a Texas A&M AgriLife Research scientist might figure out how to recruit enzymes for other jobs to benefit medical fields and industry.

"We know that enzymes usually have one biological function in a cell, but many are capable of doing something quite different, when given substrate molecules those at the beginning of a chemical reaction that they don't normally encounter," said Dr. Margy Glasner, AgriLife Research biochemist in College Station.

Glasner has received more than $767,000 in a five-year grant from the National Science Foundation to study how to make use of the so-called promiscuous enzymes those that have these hidden abilities in addition to their normal function.

"If mutations improve these hidden abilities, enzymes can evolve new functions that are useful to the organism," Glasner said. "In some cases, mutations cannot improve the promiscuous activity because the enzyme is an evolutionary deadend."

The key to the research will be understanding how and why certain enzymes are capable of functioning in new jobs so their ability could be applied to help people and the environment.

Her team is trying to determine why one enzyme can evolve a new function but another, related protein cannot. An enzyme is a protein that speeds up the rate of a chemical reaction.

Her work is part of the basic science which ultimately could have such applications as removing toxins from the environment, Glasner said.

"Bacteria are good at finding ways to degrade even pesticides invented in the 1950s. But we may be overtaxing natural evolutionary processes, given the quantity of such chemicals still in the environment," she said. "If we understood the mechanism of evolution better, we might be able to design enzymes that can tackle this problem. And because enzymes can work in water and are biodegradable, they could replace t
'/>"/>

Contact: Kathleen Phillips
ka-phillips@tamu.edu
979-845-2872
Texas A&M AgriLife Communications
Source:Eurekalert

Page: 1 2

Related biology news :

1. Promiscuous squid fatigued after mating
2. ORNL process improves catalytic rate of enzymes by 3,000 percent
3. Is it a rock, or is it Jell-O? Defining the architecture of rhomboid enzymes
4. Ancient enzymes function like nanopistons to unwind RNA
5. New inhibitors of elusive enzymes promise to be valuable scientific tools
6. Researchers use blood testing to predict level of enzymes that facilitate disease progression
7. Nutrient-sensing enzymes key to starvation response and survival in newborn mammals
8. Powerful enzymes create ethanol from agricultural harvest waste
9. Alnylam and UMass Medical School announce Tuschl I patent upheld in European opposition proceedings
10. Miniature pressure sensors for medical touch
11. Research!America says house funding levels for FY13 could undermine medical progress
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... week that the U.S. surgeon general issued a 101-page ... Montana State University published a paper breaking new ground ... cell responds when exposed to ultraviolet (UV) light. ... by the UV rays found in sunlight. This damage ... eye diseases. , "Our paper advances foundational knowledge ...
(Date:7/31/2014)... Most people are familiar with Hibiscus flowers- they ... where they are commonly planted in the landscape. ... - are endangered species. , Only a relatively ... aware of an equally beautiful and intriguing related ... literally "brother of Hibiscus". , Brother of Hibiscus ...
(Date:7/31/2014)... , July 31, 2014 ... unique and innovative smart technologies; companies turn towards digital ... EBAY ), Amazon.com Inc. (NASDAQ: AMZN ... Inc. (NASDAQ: GOOG ) and Microsoft Corporation ... company focused on the growing m-commerce market, announces a ...
Breaking Biology News(10 mins):New paper describes how DNA avoids damage from UV light 2New paper describes how DNA avoids damage from UV light 3Brother of Hibiscus is found alive and well on Maui 2Smart Technology Consumer's Interest in Mobile Payment Products Grows - Company Secures Deal with Major Airline to Display Advertisements in Flight for its Next Generation Smart Wallet 2Smart Technology Consumer's Interest in Mobile Payment Products Grows - Company Secures Deal with Major Airline to Display Advertisements in Flight for its Next Generation Smart Wallet 3Smart Technology Consumer's Interest in Mobile Payment Products Grows - Company Secures Deal with Major Airline to Display Advertisements in Flight for its Next Generation Smart Wallet 4Smart Technology Consumer's Interest in Mobile Payment Products Grows - Company Secures Deal with Major Airline to Display Advertisements in Flight for its Next Generation Smart Wallet 5Smart Technology Consumer's Interest in Mobile Payment Products Grows - Company Secures Deal with Major Airline to Display Advertisements in Flight for its Next Generation Smart Wallet 6
... cancer have remained largely unchanged over the past 60 years, ... disease with a very different theory of its origin that ... a billion years ago. In this month,s ... "physics of cancer", Paul Davies, principal investigator at Arizona State ...
... In the world, there are a lot of small ... at least convert to something useful, according to University ... dioxide, the greenhouse gas most responsible for far-reaching effects ... that can be transformed into the valuable agricultural fertilizer ...
... Ann Liebert, Inc., publishers announces the launch of ... innovative, peer-reviewed journal on this rapidly growing disruptive technology. ... 2013, and quarterly thereafter in 2014. Editor-in-Chief Hod Lipson, ... Lab at the Sibley School of Mechanical and Aerospace ...
Cached Biology News:Cancer is a result of a default cellular 'safe mode,' physicist proposes 2Diamond catalyst shows promise in breaching age-old barrier 2
(Date:7/31/2014)... July 31, 2014 According to ... "Electrodes for Medical Devices Market (Diagnostic Electrodes - ECG, ... - TENS, Pacemakers, Defibrillators, Electrosurgical and Other Electrodes) - ... 2013 - 2019," the global electrodes market for medical ... and is estimated to reach a market worth USD ...
(Date:7/31/2014)... Senomyx , Inc. (NASDAQ: ... taste science technologies to discover, develop, and commercialize ... ingredient supply industries, today reported financial results for ... second quarter with $33.6 million in cash and ... past quarter Senomyx achieved another important milestone with ...
(Date:7/31/2014)... Calif. (PRWEB) July 31, 2014 Held ... diagnosed patients with an overview of the disease and ... of drug side effects, as well as updates on ... grateful to Dr. Sandy Srinivas for organizing this educational ... of kidney cancer. “Sandy and her colleagues have put ...
(Date:7/31/2014)... Canada (PRWEB) July 31, 2014 ... some of the first transcriptome-wide analyses appearing around ... standard assay for RNA measurement. In the last ... throughput, more specific, work with smaller input amounts, ... tissues (eg, blood samples). On the bioinformatics side, ...
Breaking Biology Technology:Electrodes for Medical Devices Market Expected to Reach USD 1.45 Billion Globally in 2019: Transparency Market Research 2Electrodes for Medical Devices Market Expected to Reach USD 1.45 Billion Globally in 2019: Transparency Market Research 3Electrodes for Medical Devices Market Expected to Reach USD 1.45 Billion Globally in 2019: Transparency Market Research 4Electrodes for Medical Devices Market Expected to Reach USD 1.45 Billion Globally in 2019: Transparency Market Research 5Electrodes for Medical Devices Market Expected to Reach USD 1.45 Billion Globally in 2019: Transparency Market Research 6SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 2SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 3SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 4SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 5SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 6SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 7SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 8SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 9SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 10SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 11SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 12SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 13SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 14SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 15SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2014 FINANCIAL RESULTS 16The Evolution of RNA-Sequencing, Upcoming Live Webinar August 22 hosted by Xtalks 2
... agents is time-consuming and expensive. Pharmaceutical companies may have ... bind a target molecule before they hit upon a ... Munich led by Professor Dieter Braun, a member of ... a partner in NanoTemper (an LMU spin-off), have now ...
... New ... ... 2010 -- Model N , Inc., the leader in Revenue Management solutions, today ... Model N Revenue Management Suite by allowing business users to rapidly develop contract documents ...
... ... ... ... ...
Cached Biology Technology:A hot road to new drugs 2Model N Extends its Industry-Leading Contract Management Offerings with Contract Authoring Capabilities 2Model N Extends its Industry-Leading Contract Management Offerings with Contract Authoring Capabilities 3Model N Extends its Industry-Leading Contract Management Offerings with Contract Authoring Capabilities 4Model N Extends its Industry-Leading Contract Management Offerings with Contract Authoring Capabilities 5Transgenomic Licenses IP From IntegraGen to Develop Genetic Test for Autism 2Transgenomic Licenses IP From IntegraGen to Develop Genetic Test for Autism 3Transgenomic Licenses IP From IntegraGen to Develop Genetic Test for Autism 4Transgenomic Licenses IP From IntegraGen to Develop Genetic Test for Autism 5Transgenomic Licenses IP From IntegraGen to Develop Genetic Test for Autism 6
... for the use of small interfering RNA ... the RNA interference (RNAi) pathway have generated ... biology fields. siRNA for experimental use can ... enzymatically, and then transfected into the target ...
... potential applications for the use of small ... expression via the RNA interference,(RNAi) pathway have ... molecular biology fields. siRNA for experimental use ... enzymatically, and then transfected into the target ...
... The HybArray 12™ is an automated hybridization ... The system automates both the hybridization and ... glass slides. A single instrument can process ... in pairs and has multi-protocol software, enabling ...
... is commonly used as a fusion partner ... The GSTTag sequence has been reported to ... the solubility of its fusion partners. When ... GSTTag fusion proteins can be purified with ...
Biology Products: