Navigation Links
Progress in tissue engineering to repair joint damage in osteoarthritis
Date:6/8/2011

Medical scientists now have "clear" evidence that the damaged cartilage tissue in osteoarthritis and other painful joint disorders can be encouraged to regrow and regenerate, and are developing tissue engineering technology that could help millions of patients with those disorders. That's the conclusion of a new analysis of almost 100 scientific studies on the topic, published in ACS's journal Molecular Pharmaceutics.

Tong Cao, Wei Seong Toh and colleagues point out that damage to so-called articular cartilage the smooth, white, rubbery tissue that covers and cushions the ends of bones in joints is one of the most challenging problems in medicine. That's because the tissue lacks blood vessels and has little ability to repair itself and regrow. Wear-and-tear damage thus builds up over the years, resulting in conditions like osteoarthritis, which affects 27 million people in the United States alone. Osteoarthritis is a fast-growing public health problem because of the world's aging population and because of a sharp increase in obesity, which increases wear on joint cartilage. To assess progress toward medical use of tissue engineering to treat joint damage, the researchers scanned global research on the topic.

They found that scientists have developed many new tissue engineering methods, including implantation of so-called "scaffolds" made of biomaterials that mimic cartilage matrix in the body. The scaffolds could guide the transplanted cells, orchestrate the host cell response, provide structures and microenvironment substances to help rebuild cartilage at the injury site. "In summary, there is promise in future research involving the development of multi-functional biomaterial delivery systems that affect cartilage tissue regeneration on multiple levels," the article states.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

0

GOOD

Page: 1

Related biology news :

1. Chesapeake Bay programs 2-year milestones improve upon past strategies, but accounting of progress remains a challenge
2. GOLFIG increased progression-free survival in colorectal cancer patients
3. Progress toward the clinical application of autologous induced pluripotent stem cells and gene repair therapy for treatment of familial hypercholesterolemia
4. Older and stronger: Progressive resistance training can build muscle, increase strength as we age
5. Researchers find drug that stops progression of Parkinsons disease in mice
6. Neiker-Tecnalia makes progress in detection and prevention of infection by visna maedi virus
7. Researchers learn why PSA levels reflect prostate cancer progression
8. Progress toward treating infections by silencing microbes smart phones
9. Progress toward first commercial repellent for East Coasts stinker
10. Erlotinib improves progression-free survival as first-line therapy in advanced lung cancer
11. Gene-environmental interactions and MS progression is focus of new study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... at Emory University, along with partners at the ... million grant over four years to establish the ... Research Center: Understanding Lifetime Exposures). The grant is ... United States. , The HERCULES Center is ... Sciences (NIEHS) of the National Institutes of Health ...
(Date:5/23/2013)... DNA around nucleosomes in the cell nucleus makes ... Ludwig-Maximilians-Universitaet (LMU) in Munich now describes a mechanism ... from nucleosomes for transcription. , In higher organisms ... nucleus, wrapped around disk-shaped particles called nucleosomes, each ... proteins and accommodating two loops of DNA. Packed ...
(Date:5/23/2013)... patients unnecessarily undergo surgery or harsh treatments because ... and aggressive forms of the disease. Researchers at ... Institutes are developing technology that allows patients to ... mild treatments or take drastic measures. , The ... associate professor of biomedical engineering at Case Western ...
Breaking Biology News(10 mins):Emory, Georgia Tech receive first human exposome center grant in US 2Emory, Georgia Tech receive first human exposome center grant in US 3Biochemistry: Unspooling DNA from nucleosomal disks 2Using big data to identify prostate cancers and best treatments 2Using big data to identify prostate cancers and best treatments 3
... Package: Special National Meeting Edition ,Aug. 22, 2007 ... IS EMBARGOED FOR VARIOUS TIMES AS INDICATED PressPac ... use only: For full information about the Boston meeting, ... to abstracts of more than 9,500 scientific papers, and ...
... heart muscle cells derived from embryonic stem cells are ... can help rebuild the animal,s heart muscle and improve ... issue of Nature Biotechnology. The researchers also developed a ... turned into heart muscle cells and then survive after ...
... an evolutionary dead end and could have a long term ... University. Previous studies have found that the giant ... led to a lack of genetic diversity that will inevitably ... by Professor Michael Bruford and Dr Benot Goossens from the ...
Cached Biology News:American Chemical Society's Weekly Press Pac 2American Chemical Society's Weekly Press Pac 3American Chemical Society's Weekly Press Pac 4American Chemical Society's Weekly Press Pac 5American Chemical Society's Weekly Press Pac 6American Chemical Society's Weekly Press Pac 7American Chemical Society's Weekly Press Pac 8American Chemical Society's Weekly Press Pac 9Human derived stem cells can repair rat hearts damaged by heart attack 2Human derived stem cells can repair rat hearts damaged by heart attack 3
(Date:5/23/2013)... MD (PRWEB) May 23, 2013 Can ... off from work motivate members of the public to ... researchers including Johns Hopkins Carey Business School ... emphatic yes. Pointing to a large body of recent ... in the May 24, 2013, issue of Science that ...
(Date:5/23/2013)... 2013 Patheon Inc ., a ... the global pharmaceutical industry, will host a complimentary webinar ... Testing” on Tuesday, June 4, 2013 at 11 a.m. ... required to comply with regulations for cleaning validation. ... scientific underpinning and little evaluation of risk. Some ...
(Date:5/23/2013)... 23, 2013  Rahal Letterman Lanigan Racing (RLL) and ... stem cell banking and therapeutics, announced today that StemCyte ... Acorn Stairlifts Indy car driven by James ... the IZOD IndyCar 2013 season.   StemCyte, ... support awareness of umbilical cord blood banking and its ...
(Date:5/23/2013)... 2013 PI’s new LPS-24 positioners ... 15 mm travel range with closed-loop sensor resolution ... make these new positioners the ideal choice for ... rated version is also available. , More ... can be found at: , http://www.physikinstrumente.com/en/products/prdetail.php?sortnr=1000745&prw-lps24 ...
Breaking Biology Technology:Offering Economic Incentives to Attract Blood Donations Should Be Encouraged, Research Team writes in Science 2Offering Economic Incentives to Attract Blood Donations Should Be Encouraged, Research Team writes in Science 3Patheon to Present on “Cleaning Validation: Science, Risk and Novel Approaches to Testing” 2StemCyte, Inc. Joins Rahal Letterman Lanigan Racing As Associate Sponsor Of No. 16 IndyCar Program For James Jakes Beginning With The 97th Indianapolis 500 2StemCyte, Inc. Joins Rahal Letterman Lanigan Racing As Associate Sponsor Of No. 16 IndyCar Program For James Jakes Beginning With The 97th Indianapolis 500 3Precision Positioning System Uses Miniaturezed Piezo Linear Motor: LPS-24 Linear Stage by PI 2
... Additional "FOR" Votes Required for Integra Merger, IRVINE, ... ("IsoTis"), an orthobiologics company, today reported that,less than 100,000 ... by Integra LifeSciences Holdings Corporation (NASDAQ: IART ),("Integra") ... as of August,6, 2007. Today,s special meeting of ...
... 26 PURE Bioscience (OTC,Bulletin Board: PURE), creators ... in a revolutionary new hard surface,disinfectant which kills ... the Company will present at the Biocom Investor ... Diego Marriott Del Mar. Michael L.,Krall, CEO, will ...
... Oct. 26 Pharmasset, Inc.,(Nasdaq: VRUS ) management will be ... Acumen BioFin Rodman & Renshaw 9th Annual Healthcare Conference being ... York Palace Hotel in New York City. ... Officer, will provide an overview of the company on Tuesday, ...
Cached Biology Technology:IsoTis Reports Status of Merger Vote 2IsoTis Reports Status of Merger Vote 3IsoTis Reports Status of Merger Vote 4PURE Bioscience to Present at Biocom Investors Conference 2PURE Bioscience to Present at Biocom Investors Conference 3PURE Bioscience to Present at Biocom Investors Conference 4Pharmasset to Present at Three Investor Conferences in November 2007 2