Navigation Links
Professor publishes on first-ever imaging of cells growing on spherical surfaces
Date:9/21/2012

MELBOURNE, FLA.Shengyuan Yang, Florida Institute of Technology assistant professor of mechanical and aerospace engineering, with graduate student Sang Joo Lee, has published a paper on the first-ever imaging of cells growing on spherical surfaces. The paper is published in the online journal, Review of Scientific Instruments, and will appear later in September in the print version.

The potential biomedical applications of the researchers' technique include new strategies and devices for the early detection and isolation of cancer cells, facilitating new methods of treating cancer tissues. "We also foresee new strategies and techniques to control the differentiation of stem cells and the morphologies and structures of the resulting cells and tissues," said Yang.

The effects of substrate stiffness on cell behaviors have been extensively studied; however, the effects of substrate curvature are not well-documented. The curvature of the surface on which cells adhere can have profound effects on cell behaviors, according to Yang.

"To reveal these cell mechano-biological responses to substrate curvatures, we have introduced a novel, simple, and flexible class of substrates, polyacrylamide gels embedded with micro glass balls ranging in diameter from 5 mm to 2 mm, to culture cells. To the best of our knowledge, this is the first experimental attempt to study cell responses to spherically-shaped substrates. Our cell culture experiments imply that this class of substrates, micro glass ball embedded gels, can be useful tools to study cell mechanobiological responses to substrate curvatures, related cell and tissue engineering researches, and biomedical applications, such as cancer detection and treatment, and the control of stem cell differentiations, for example," said Yang.

This work was supported with funding from the National Science Foundation (NSF) CAREER Program. The reviewer of this paper at Review of Scientific Instruments commented, according to Yang: "This is a clever idea. . . This work has great potentials with high impact."


'/>"/>

Contact: Karen Rhine
krhine@fit.edu
321-674-8964
Florida Institute of Technology
Source:Eurekalert

Related biology news :

1. Study by Haverford College professor reveals unprecedented impact of Deepwater Horizon on deep ocean
2. A University of Tennessee professors hypothesis may be game changer for evolutionary theory
3. Scripps Research Institute Professor Gerald F. Joyce elected to American Academy of Arts & Sciences
4. Professor known for work with hunter-gatherers elected to American Academy of Arts and Sciences
5. Mainz University Medical Center attracts funding of Alexander von Humboldt Professorship
6. NJIT professor awarded patent today for new desalination devices, more
7. UI professor identifies largest known crocodile
8. Biology professor secures grant to save West Virginias primary natural history collection
9. Florida Tech biological sciences professor earns $257,000 NSF grant to study coral diseases
10. Purdue professor to speak before Congress about nanotechnology in brain treatment research
11. Normal bacterial makeup has huge implications for health, says CU professor
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/8/2017)... YORK , Feb. 7, 2017 ... Driven largely by the confluence of organizations, desires ... distaste for knowledge-based systems (password and challenge questions), ... industrial, and government systems. The market is driven ... a demarcation between consumer and enterprise uses cases, ...
(Date:2/7/2017)... BEACH, New York , February 7, 2017 /PRNewswire/ ... known as ID Global Solutions Corporation [OTC: IDGS], ("Ipsidy" ... identity management and electronic transaction processing services, is pleased ... reorganization of the Company. Effective January 31, ... of the Board of Directors, CEO and President.  An ...
(Date:2/2/2017)... Feb. 2, 2017   TapImmune, Inc. ... company specializing in the development of innovative peptide ... of cancer and metastatic disease, announced today it ... manufacturing of a second clinical lot of TPIV ... receptor alpha. The manufactured vaccine product will be ...
Breaking Biology News(10 mins):
(Date:2/18/2017)... 2017 Kurzlehrgang mit Fokus ... Zelltherapie-Studien, Poster legt metaproteomische Analyse des Darm-Mikrobioms bei Säuglingen ... ... Dr. Yoav Peretz , Scientific Director bei ImmuneCarta, ... Assays zum Nachweis intrazellulärer Zytokine bei adoptiven Zelltherapie-Studien im ...
(Date:2/18/2017)... ... February 17, 2017 , ... ... business in Hong Kong. , Nerium International is proud to introduce its Age-Defying ... Contour Cream, NeriumAD™ Formula to consumers across Hong Kong. The luxury skincare products ...
(Date:2/17/2017)... PUNE, India , February 17, 2017 /PRNewswire/ ... research report "Biomarkers Market by Product (Consumables, Service), ... Disorders), Application (Diagnostics Development, Drug Discovery and Development, ... MarketsandMarkets, the market is projected to reach USD ... in 2016, growing at a CAGR of 13.8% ...
(Date:2/17/2017)... 17, 2017  If only one in every ... mutation-conferring resistance to chemotherapy, thousands of cancer cells ... focused on finding these mutations in ever-smaller subpopulations ... tumor DNA in blood — to guide treatment ... Unfortunately, however, detecting these genetic anomalies may ...
Breaking Biology Technology: