Navigation Links
Professor publishes on first-ever imaging of cells growing on spherical surfaces
Date:9/21/2012

MELBOURNE, FLA.Shengyuan Yang, Florida Institute of Technology assistant professor of mechanical and aerospace engineering, with graduate student Sang Joo Lee, has published a paper on the first-ever imaging of cells growing on spherical surfaces. The paper is published in the online journal, Review of Scientific Instruments, and will appear later in September in the print version.

The potential biomedical applications of the researchers' technique include new strategies and devices for the early detection and isolation of cancer cells, facilitating new methods of treating cancer tissues. "We also foresee new strategies and techniques to control the differentiation of stem cells and the morphologies and structures of the resulting cells and tissues," said Yang.

The effects of substrate stiffness on cell behaviors have been extensively studied; however, the effects of substrate curvature are not well-documented. The curvature of the surface on which cells adhere can have profound effects on cell behaviors, according to Yang.

"To reveal these cell mechano-biological responses to substrate curvatures, we have introduced a novel, simple, and flexible class of substrates, polyacrylamide gels embedded with micro glass balls ranging in diameter from 5 mm to 2 mm, to culture cells. To the best of our knowledge, this is the first experimental attempt to study cell responses to spherically-shaped substrates. Our cell culture experiments imply that this class of substrates, micro glass ball embedded gels, can be useful tools to study cell mechanobiological responses to substrate curvatures, related cell and tissue engineering researches, and biomedical applications, such as cancer detection and treatment, and the control of stem cell differentiations, for example," said Yang.

This work was supported with funding from the National Science Foundation (NSF) CAREER Program. The reviewer of this paper at Review of Scientific Instruments commented, according to Yang: "This is a clever idea. . . This work has great potentials with high impact."


'/>"/>

Contact: Karen Rhine
krhine@fit.edu
321-674-8964
Florida Institute of Technology
Source:Eurekalert

Related biology news :

1. Study by Haverford College professor reveals unprecedented impact of Deepwater Horizon on deep ocean
2. A University of Tennessee professors hypothesis may be game changer for evolutionary theory
3. Scripps Research Institute Professor Gerald F. Joyce elected to American Academy of Arts & Sciences
4. Professor known for work with hunter-gatherers elected to American Academy of Arts and Sciences
5. Mainz University Medical Center attracts funding of Alexander von Humboldt Professorship
6. NJIT professor awarded patent today for new desalination devices, more
7. UI professor identifies largest known crocodile
8. Biology professor secures grant to save West Virginias primary natural history collection
9. Florida Tech biological sciences professor earns $257,000 NSF grant to study coral diseases
10. Purdue professor to speak before Congress about nanotechnology in brain treatment research
11. Normal bacterial makeup has huge implications for health, says CU professor
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2020)... ... July 30, 2020 , ... ... II contract awarded by the Joint Science & Technology Office—Chemical and Biological Defense ... to develop, optimize, and scale-up a highly efficient mammalian cell culture-based bioprocess suitable ...
(Date:7/18/2020)... ... July 17, 2020 , ... Commercial launch readiness is a critical ... discover a COVID cure or vaccine, the global economic downturn will only increase price ... not going away and capturing full value from every product launch is critical. However, ...
(Date:7/2/2020)... CITY, Calif. (PRWEB) , ... July 01, 2020 ... ... biotech company, presented its phase 1a findings of Neihulizumab, a biologic for the ... conference in June 2020. Led by hemato-oncologist Dr. Paul J Martin of the ...
Breaking Biology News(10 mins):
(Date:8/3/2020)... , ... August 03, 2020 , ... Introducing Ardent Animal ... transformative growth, , Known as MediVet Biologics since its formation ... The new Ardent Animal Health will build on its base of innovative ...
(Date:7/31/2020)... ... July 29, 2020 , ... ... transmitter systems that can be configured to drive Klystrons, TWTs, IOTs, and magnetrons. ... drive one or two switches in a push-pull configuration; yielding fast fall time ...
(Date:7/31/2020)... ... 2020 , ... eSource has long been touted as the solution to high ... eSource, the reasons it did not take off as quickly as people initially expected, ... is moving towards capturing data electronically for clinical trials and then repurposing it for ...
(Date:7/22/2020)... , ... July 22, 2020 , ... Join experts from ... Lorenc, Sr. Manager Regulatory Solutions, in a one hour live webinar on ... regulating body in China for drugs and medical devices. Specifically, for medical devices, the ...
Breaking Biology Technology: