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Process important to brain development studied in detail
Date:11/7/2011

n take place either in direct connection with the formation of RNA or after the entire RNA molecule has been formed, but in the past it was not possible to measure directly in tissue sample which is the more common in human cells. In the current study the researchers show that introns are often removed in direct connection with the formation of RNA.

We demonstrate that this rapid removal of introns is more common than was previously thought, which indicates that the formation of RNA and the regulation of protein variants are strongly connected, says first author Adam Ameur, a bioinformatician at the Department of Immunology, Genetics, and Pathology.

This is important knowledge for our understanding of regulatory mechanisms for genes that are necessary for brain development.


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Contact: Lars Feuk
lars.feuk@igp.uu.se
070-167-9425
Uppsala University
Source:Eurekalert

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