Navigation Links
Problem of fake medicines in developing countries could be solved
Date:9/1/2010

Counterfeiting of drugs is a huge industry with an annual turnover of more than SEK 500 billion. In Africa the situation is extremely serious. Half of the malaria medication sold there could be ineffective or even harmful. Researchers from Lund and the UK have now developed a technique that could resolve the situation.

In two years the researchers hope to have a prototype ready. It will resemble a small briefcase, in which a pharmacist, customs officer or pharmaceuticals agent can place a packet of tablets, without having to open the packet. After a minute or so the device indicates whether or not the medicine is fake.

"There are a number of advantages to this technique. It is not only reliable but also simple and cheap, which is a prerequisite if it is to be successfully put into use in developing countries", comments Andreas Jakobsson, Professor in Mathematical Statistics at Lund University and one of the researchers on the project.

The technique has its origins in the research that Andreas Jakobsson's Swedish and British colleagues usually conduct: detection of bombs and explosives. The researchers have been called on by HM Revenue and Customs in the UK to detect explosives at Heathrow Airport.

The research is based on a technique known as nuclear magnetic resonance. By exposing a substance to radio waves, the spin of the atom nuclei changes briefly. When the radio pulse is over and the resonance returns to normal, a weak signal, unique to each substance, is emitted. In this way, the researchers can usually work out what chemical substances are hiding in the material.

Researchers have long known that it should also be possible to use this technique to trace counterfeit drugs, but it has not been sufficiently well developed for this purpose. However, a recent breakthrough in the Swedish-British research group's work has changed that. Now they can also find out if a certain drug actually contains the active ingredient that the packaging claims.

"The signals that are emitted from a chemical substance are incredibly weak! But we have succeeded in developing mathematical algorithms which allow us to capture them. We have also managed to filter out interference from metals, for example, which are often found both in explosives and in the protective packaging around tablets", explains Andreas Jakobsson.

Professor Jakobsson and his Swedish colleague Erik Gudmundson are responsible for the mathematical calculations, while their colleagues at King's College London are responsible for the chemical experiments and the development of the equipment.

The researchers were recently awarded funding from the Wellcome Trust to develop a prototype. The Swedish research group is also funded by the Swedish Research Council and the Carl Trygger Foundation.

Counterfeit drugs are usually manufactured in factories in China and India and sold by the mafia and other criminal organisations. At best the drug only contains harmless binders.

However, sometimes the manufacturers add rat poison or other cheap but harmful substances that can easily be formed into tablets. Some contain a weak dose of the active ingredient, which can be particularly harmful in the case of penicillin, for example, when it is important to ensure that all the bacteria are killed.

Some counterfeit products work, but entail a loss of revenue for pharmaceutical companies. Even if the problem is greatest in developing countries (in India, it is estimated that 15󈞀 per cent of all drugs are fake), counterfeit drugs are also found in Europe. Most of the drugs that can be purchased on the Internet are counterfeit.


'/>"/>

Contact: Kristina Lindgrde
kristina.lindgarde@kansli.lth.se
Swedish Research Council
Source:Eurekalert

Related biology news :

1. Prenatal exposure to pesticides linked to attention problems
2. Developmental problems: Some exist in the genes
3. Children with brain injuries have problems with story-telling
4. Preventing heart problems while keeping a cool head
5. Researchers apply computing power to crack egg shell problem
6. Gender-bending fish problem in Colorado creek mitigated by treatment plant upgrade
7. Study suggests a much earlier onset for bone problems
8. Chemicals that eased one environmental problem may worsen another
9. Eczema in early childhood and psychological problems
10. Mediterranean diet may lower risk of brain damage that causes thinking problems
11. Communication problems in the brain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/7/2016)... TORONTO , June 7, 2016  Syngrafii ... begun a business relationship that includes integrating Syngrafii,s ... pilot branch project. This collaboration will result in ... for the credit union, while maintaining existing document ... http://photos.prnewswire.com/prnh/20160606/375871LOGO ...
(Date:6/2/2016)... , June 2, 2016   The Weather Company ... announcing Watson Ads, an industry-first capability in which consumers will ... being able to ask questions via voice or text and ... Marketers have long sought an ... consumer, that can be personal, relevant and valuable; and can ...
(Date:5/24/2016)... 24, 2016 Ampronix facilitates superior patient care by providing unparalleled technology to ... display is the latest premium product recently added to the range of products distributed ... ... ... Imaging- LCD Medical Display- Ampronix News ...
Breaking Biology News(10 mins):
(Date:12/2/2016)... ... December 01, 2016 , ... The Conference Forum has announced that the ... will take place on February 1-3, 2017 at the Roosevelt Hotel in New York ... program provides a unique 360-degree approach, which addresses the most up-to-date information regarding business ...
(Date:12/2/2016)... ... 01, 2016 , ... Orthogonal, a Chicago-based medical device software ... II 510(k) clearance for their flagship medical device, SimplECG. , With this FDA ... that rely on cloth-based nanosensors. While other companies have attempted to focus on ...
(Date:12/2/2016)... ... 2016 , ... Robots will storm the Prudential Center in Boston, MA during ... which is held on the United Nations International Day of Persons with Disabilities, will ... workplace. Suitable Technologies is partnering with NTI to showcase how technology can help individuals ...
(Date:12/2/2016)... , December 2, 2016 The immunohistochemistry ... growing at a CAGR of 7.3% during the forecast period of ... and diagnostic laboratories segment accounted for the largest share of immunohistochemistry ... ... on global immunohistochemistry (IHC) market spread across 225 pages, profiling 10 ...
Breaking Biology Technology: