Navigation Links
Probiotic bacteria could help treat Crohn's disease
Date:3/31/2011

New research suggests that infection with a probiotic strain of E. coli bacteria could help treat an reduce the negative effects of another E. coli infection that may be associated with Crohn's disease. Researchrs from the University of Auckland, New Zealand publish their results in the April 2011 issue of the journal Applied and Environmental Microbiology.

Crohn's disease is a common chronic disorder that affects the gastrointestinal tract and is believed to develop as a result of an aberrant immune response to intestinal microbes in a genetically susceptible host. Over the last decade, high levels of adherent invasive E. coli (AIEC) have been reported. One study isolated the bacteria in 36% of Crohn's sufferers compared to just 6% of controls.

Since Crohn's disease is a clinical subtype of inflammatory bowel disease (IBD) and others have reported successful treatment of IBC with the probiotic E. coli Nissle 1917 (EcN), the researchers investigated the impact EcN might have on an already established infection with AIEC in cell cultures mimicking those found in the lining of the intestines.

They found that treatment with EcN not only helped prevent the AIEC reference strain LF82 from invading the cells and establishing infection, it also appears to modulate production of immune proteins that cause inflammation.

"This study is the first to our knowledge to show that EcN can reduce some of the negative effects associated with the strain LF82 in an already established AIEC infection and emphasizes the potential of EcN in IBD treatment. In particular the use of this probiotic could be of interest in CD patients harboring pathogenic AIEC," write the researchers.


'/>"/>

Contact: Jim Sliwa
jsliwa@asmusa.org
American Society for Microbiology
Source:Eurekalert

Page: 1

Related biology news :

1. Probiotics and Health Claims
2. Probiotic identified to treat ulcers
3. Probiotics, prebiotics and biofuel-producing bacteria
4. Probiotic found in breast milk helps alleviate symptoms of digestive disorders
5. Probiotics help extremely premature infants gain weight
6. Probiotic without effect against Salmonella
7. A sticky solution for identifying effective probiotics
8. Probiotic found to be effective treatment for colitis in mice
9. Designing probiotics that ambush gut pathogens
10. Probiotics help gastric-bypass patients lose weight more quickly, Stanford study shows
11. Review of probiotic trial research finds only Bifantis able to claim efficacy for IBS symptoms
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/16/2017)... 16, 2017   Bridge Patient Portal , ... MD EMR Systems , an electronic medical ... GE, have established a partnership to build an ... the GE Centricity™ products, including Centricity Practice Solution ... These new integrations will allow healthcare delivery ...
(Date:4/18/2017)... 18, 2017  Socionext Inc., a global expert in SoC-based imaging ... server, the M820, which features the company,s hybrid codec technology. A ... Tera Probe, Inc., will be showcased during the upcoming Medtec Japan ... at the Las Vegas Convention Center April ... Click here for ...
(Date:4/11/2017)... , April 11, 2017 Crossmatch®, a ... authentication solutions, today announced that it has been ... Research Projects Activity (IARPA) to develop next-generation Presentation ... "Innovation has been a driving force ... program will allow us to innovate and develop ...
Breaking Biology News(10 mins):
(Date:5/23/2017)... (PRWEB) , ... May 22, 2017 , ... ... and Photonics 2017 in San Diego, California, this August will feature high-level ... fuels, and autonomous vehicles. , SPIE Optics and Photonics, the largest multidisciplinary optical ...
(Date:5/23/2017)... ... May 23, 2017 , ... Cambridge Semantics , the leading provider ... Bio-IT World Conference and Expo in Boston May 23-25 with a featured ... The Anzo Smart Data Lake is also a finalist for the Best of Show ...
(Date:5/21/2017)... CA (PRWEB) , ... May 19, 2017 , ... ... annual meeting and educational conference of the American Association of Bioanalysts (AAB) and ... Galleria Hotel in Houston. The conference reinforces AAB’s commitment to excellence in clinical ...
(Date:5/18/2017)... ... May 18, 2017 , ... ... Tapas Cooking Challenge is a two-hour team-building package designed for groups of 10-30 ... Chef Jodi Abel, which include items, such as Blackened Shrimp with Edamame Salad, ...
Breaking Biology Technology: