Navigation Links
Princeton research: In the early life of an embryo, a monster lurks
Date:8/22/2011

lopmental timetable. The finding revealed a crucial role for the somewhat puzzling existence of the calcium wave, as well as a new level of sophistication in how embryos function.

"We didn't have to go searching for chaos, it just came right out at us," Wingreen said. "When the dust settled, it became clear that cell-cycle oscillation, while remarkably uniform in the end, does not come by that harmony on its own, especially not in anything as big as an embryo, which is much larger than a typical cell. But then the question became, if there's this potential for chaos, how does the system avoid it? It turns out that the system needs the calcium wave to avoid chaos and that wave is activated surprisingly fast."

The embryo's need for stabilization and the dual role of the calcium wave illuminates the intricacy of developing embryos, as well as the impressive ability of embryos to prevent their own destruction, said James Ferrell, a Stanford University professor of chemical and systems biology. The Princeton researchers based their work on formulas that Ferrell developed from experiments on African clawed frog embryos that describe how embryos divide and replicate in timed cycles during early development.

"One of this group's conclusions is that chaos lurks not far from where the system normally functions, like a monster in the corner, and that it matters to have synchronicity established quickly to prevent it. That's not something we had initially thought about," said Ferrell, who had no involvement in the Princeton-led research, but is interested in testing the results experimentally.

"They present a nice story of how evolution has come up with a way to do things as fast as is needed to avoid chaos, but not too much faster. It's deepened our appreciation of what is happening in the biological system, and is a good example of how theory and careful modeling can reveal functions that might not appear in experiments."

Wingree
'/>"/>

Contact: Morgan Kelly
mgnkelly@princeton.edu
609-258-5729
Princeton University
Source:Eurekalert

Page: 1 2 3 4 5

Related biology news :

1. Princeton scientists construct synthetic proteins that sustain life
2. Princeton researchers find that high-fructose corn syrup prompts considerably more weight gain
3. Princeton scientists find way to catalog all that goes wrong in a cancer cell
4. NCI awards $15.2 million to create Princeton Physical Sciences -- Oncology Center
5. Princeton team learns why some drugs pack such a punch
6. Princeton teams analysis of flu virus could lead to better vaccines
7. Princeton geoscientist offers new evidence that meteorite did not wipe out dinosaurs
8. Princeton researchers discover new type of laser
9. Princeton-led team finds secret ingredient for the health of tropical rainforests
10. MS research: Myelin influences how brain cells send signals
11. USC research: Cancer cells and stem cells share same origin
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... BostonThe American Society for Bone and Mineral Research awarded ... of Medicine (BUSM), with the 2014 Louis V. Avioli ... at BUSM, is internationally known for revolutionizing the understanding ... , The award honors a member of the ... fundamental contributions to bone and mineral basic research. It ...
(Date:7/11/2014)... of Standards and Technology (NIST) need a special ... often prove that necessity is truly the mother ... M. Lorna De Leoz and Stephen Stein, NIST ... Glycomics is the study of the abundant, often-branched ... proteins and lipids and influence cellular processes, including ...
(Date:7/11/2014)... of researchers, including scientists from the Max Planck Institute ... a major step in understanding photosynthesis, the process by ... oxygen in its atmosphere and which is therefore crucial ... , The researchers report the first direct visualization of ... step in which a specific protein complex, photosystem II, ...
Breaking Biology News(10 mins):BUSM's Michael F. Holick receives American Society for Bone and Mineral Research award 2A first direct glimpse of photosynthesis in action 2
... Chinese . College Park, MD (August 3, 2010) ... in molecular biology today. The devices, which can be used ... sequences, are employed in everything from forensic analysis to disease ... colleagues at Simon Fraser University in Burnaby, Canada have combined ...
... YORK, N.Y., August 3, 2010) Autism Speaks, ... importance of research on environmental risk factors for ... on Environment & Public Works, Subcommittee on Children,s ... health factors associated with autism spectrum disorders (ASD) ...
... of dollars to cap it, and it could take billions ... Gulf of Mexico is acknowledged the environmental catastrophe of the ... help "bioremediate" the remaining problems. Prof. Eugene Rosenberg ... Molecular Microbiology and Biotechnology are using naturally occurring oil-munching bacteria, ...
Cached Biology News:Autism Speaks on US Senate hearing on potential environmental health factors in autism 2Autism Speaks on US Senate hearing on potential environmental health factors in autism 3A nemesis for oil spills 2
(Date:7/10/2014)... Calabasas, CA (PRWEB) July 10, 2014 ... academic institutions and professional associations, addressed the challenges of ... & Medical Device Industries” through strategic sourcing. Describing the ... ) with the Supply Chain Management Institute ( SCMI) ... the event on June 24 at the Kroc Institute ...
(Date:7/10/2014)... , July 10, 2014 Research ... addition of the "International Photonic Integrated Circuit ... Forecasts to 2019" report to their offering. ... The concept of photonic integration traces its ... century. The promise of photonic integration went unexplored ...
(Date:7/10/2014)... study published today in the journal PNAS (Proceedings ... that time of day and sleep deprivation have a ... crucial when looking at the best time of day ... disease, and for administering medicines effectively. , Researchers from ... Research, London, investigated the links between sleep deprivation, body ...
(Date:7/10/2014)... out for crude 3-D glasses, polarized glasses, and ... basic devices, used to trick the brain into ... rendered obsolete with the introduction of new holography ... TAU doctoral students Yuval Yifat, Michal Eitan, and ... on nanoantennas that could be used for security ...
Breaking Biology Technology:Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 2Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 3Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 4International Photonic Integrated Circuit (Monolithic Integration, Hybrid Integration, Module Integration) Market - Forecasts to 2019 2Time of day crucial to accurately test for diseases, new research finds 2Projecting a 3-dimensional future 2Projecting a 3-dimensional future 3
... would let you see a virus in a drop of blood ... says Durdu Guney, make ultra-high-resolution microscopes as commonplace as cameras in ... also known as a perfect lens, though people are trying. Optical ... limit, so even the best won,t usually let us see objects ...
... of electronics at the nanoscale may be even ... conductance in ferroelectric nanodomains by researchers at Oak ... their polarization with the application of an electric ... as ultrasound machines and sensors. Now, discoveries about ...
... 2012 Advanstar|CBI recently announced the full agenda for ... Forum takes place March 6-7, 2012 in Baltimore, MD. ... Eli Lilly, Genentech, AstraZeneca, Shire Human Genetic Therapies and ... Needy Meds recently interviewed PAP,s Senior Program Manager, Sharon ...
Cached Biology Technology:Almost perfect: A breakthrough in superlens development 2ORNL experiments prove nanoscale metallic conductivity in ferroelectrics 2
... MagicMark XP Western Protein Standards are ... protein molecular weight estimation directly on ... an IgG binding site, allowing direct ... used to detect your target protein ...
... TOPO Cloning is ... available for cloning PCR ... and Zero Blunt TOPO ... and activated with topoisomerase ...
... Conjugated peptides or recombinant proteins ... to produce antibodies in 2 rabbits. pre-immune ... ELISA test until the titer reaches 1:4,000 ... Protein G purification Antibodies are eluted ...
... Immunogen: Recombinant human IDO ... for the ~44 kDa human ... (positive control: IFN-Gamma-stimmulated Human peripheral ... homology reactivity with mouse and ...
Biology Products: